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Gene: MIR203A (microRNA 203a) Homo sapiens
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Symbol: MIR203A
Name: microRNA 203a
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: hsa-mir-203a; miR-203; mir-203a; MIR203; MIRN203; miRNA203
Orthologs:
No known orthologs. homologs ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl14104,117,405 - 104,117,514 (+)EnsemblGRCh38hg38GRCh38
GRCh3814104,117,405 - 104,117,514 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3714104,583,742 - 104,583,851 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614103,653,494 - 103,653,603 (+)NCBINCBI36hg18NCBI36
Celera1484,637,945 - 84,638,054 (+)NCBI
Cytogenetic Map14q32.33NCBI
HuRef1484,763,577 - 84,763,686 (+)NCBIHuRef
CHM1_114104,522,200 - 104,522,309 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
References - curated
References - uncurated

Genomics

miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MIR203A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1345431
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.