UBP1 (upstream binding protein 1) - Rat Genome Database
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Gene: UBP1 (upstream binding protein 1) Homo sapiens
Analyze
Symbol: UBP1
Name: upstream binding protein 1
RGD ID: 1345367
HGNC Page HGNC
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of viral transcription and positive regulation of transcription by RNA polymerase II. Localizes to cytosol and nucleoplasm; INTERACTS WITH acrolein; alpha-pinene; arsane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp686L1745; LBP-1a; LBP-1B; LBP1A; LBP1B; transcription factor LBP-1; upstream binding protein 1 (LBP-1a); upstream-binding protein 1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl333,388,336 - 33,441,371 (-)EnsemblGRCh38hg38GRCh38
GRCh38333,388,336 - 33,440,405 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37333,429,828 - 33,481,897 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36333,404,835 - 33,456,874 (-)NCBINCBI36hg18NCBI36
Build 34333,404,834 - 33,456,874NCBI
Celera333,373,357 - 33,425,407 (-)NCBI
Cytogenetic Map3p22.3NCBI
HuRef333,370,390 - 33,422,369 (-)NCBIHuRef
CHM1_1333,379,810 - 33,431,856 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
1. GOA_HUMAN data from the GO Consortium
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2006421   PMID:7836461   PMID:8114710   PMID:10644752   PMID:12477932   PMID:14702039   PMID:15207707   PMID:15471945   PMID:15489334   PMID:16344560   PMID:18004979   PMID:19274049  
PMID:19322201   PMID:19505873   PMID:19662162   PMID:19751393   PMID:20211142   PMID:21873635   PMID:21956701   PMID:21988832   PMID:22939629   PMID:25544563   PMID:25609649   PMID:25852190  
PMID:26186194   PMID:26496610   PMID:26673895   PMID:26760575   PMID:28473536   PMID:28514442   PMID:28533407   PMID:29410248   PMID:29509190   PMID:29844126   PMID:30021884   PMID:30804502  
PMID:31527615   PMID:32296183   PMID:32694731   PMID:32780723  


Genomics

Comparative Map Data
UBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl333,388,336 - 33,441,371 (-)EnsemblGRCh38hg38GRCh38
GRCh38333,388,336 - 33,440,405 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37333,429,828 - 33,481,897 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36333,404,835 - 33,456,874 (-)NCBINCBI36hg18NCBI36
Build 34333,404,834 - 33,456,874NCBI
Celera333,373,357 - 33,425,407 (-)NCBI
Cytogenetic Map3p22.3NCBI
HuRef333,370,390 - 33,422,369 (-)NCBIHuRef
CHM1_1333,379,810 - 33,431,856 (-)NCBICHM1_1
Ubp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399113,760,002 - 113,807,095 (+)NCBIGRCm39mm39
GRCm389113,930,939 - 113,978,027 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9113,930,934 - 113,977,202 (+)EnsemblGRCm38mm10GRCm38
MGSCv379113,840,052 - 113,886,320 (+)NCBIGRCm37mm9NCBIm37
MGSCv369113,780,350 - 113,825,700 (+)NCBImm8
Celera9113,640,161 - 113,686,339 (+)NCBICelera
Cytogenetic Map9F3NCBI
Ubp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28113,869,771 - 113,915,625 (+)NCBI
Rnor_6.0 Ensembl8122,197,027 - 122,240,357 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.08122,196,576 - 122,241,368 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08121,510,557 - 121,554,898 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48118,574,348 - 118,618,657 (+)NCBIRGSC3.4rn4RGSC3.4
Celera8113,117,821 - 113,162,107 (+)NCBICelera
Cytogenetic Map8q32NCBI
Ubp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955421618,696 - 681,994 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955421618,696 - 681,994 (-)NCBIChiLan1.0ChiLan1.0
UBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1333,611,712 - 33,663,175 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl333,611,712 - 33,663,175 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0333,310,506 - 33,362,589 (-)NCBIMhudiblu_PPA_v0panPan3
UBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl233,444,758 - 3,497,263 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1233,445,730 - 3,498,242 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ubp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647323,658,243 - 23,711,768 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1319,204,947 - 19,276,969 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11319,203,965 - 19,276,392 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21320,785,120 - 20,831,156 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UBP1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11577,880,650 - 77,933,829 (-)NCBI
ChlSab1.1 Ensembl1577,882,632 - 77,933,864 (-)Ensembl
Ubp1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478811,350,243 - 11,409,942 (-)NCBI

Position Markers
STS-N49886  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37333,455,228 - 33,455,431UniSTSGRCh37
Build 36333,430,232 - 33,430,435RGDNCBI36
Celera333,398,738 - 33,398,941RGD
Cytogenetic Map3p22.3UniSTS
HuRef333,395,771 - 33,395,974UniSTS
GeneMap99-GB4 RH Map3116.05UniSTS
SHGC-149141  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37333,456,836 - 33,457,179UniSTSGRCh37
Build 36333,431,840 - 33,432,183RGDNCBI36
Celera333,400,346 - 33,400,689RGD
Cytogenetic Map3p22.3UniSTS
HuRef333,397,379 - 33,397,722UniSTS
TNG Radiation Hybrid Map320730.0UniSTS
SHGC-149281  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37333,456,579 - 33,456,858UniSTSGRCh37
Build 36333,431,583 - 33,431,862RGDNCBI36
Celera333,400,089 - 33,400,368RGD
Cytogenetic Map3p22.3UniSTS
HuRef333,397,122 - 33,397,401UniSTS
TNG Radiation Hybrid Map320744.0UniSTS
SHGC-76821  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37333,429,962 - 33,430,170UniSTSGRCh37
Build 36333,404,966 - 33,405,174RGDNCBI36
Celera333,373,491 - 33,373,699RGD
Cytogenetic Map3p22.3UniSTS
TNG Radiation Hybrid Map320794.0UniSTS
GeneMap99-GB4 RH Map3124.84UniSTS
NCBI RH Map3349.4UniSTS
D3S3159  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3p22.3UniSTS
HuRef333,415,953 - 33,416,195UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2796
Count of miRNA genes:920
Interacting mature miRNAs:1088
Transcripts:ENST00000283628, ENST00000283629, ENST00000411650, ENST00000447368, ENST00000456378, ENST00000464787, ENST00000466441, ENST00000467613, ENST00000481761, ENST00000486388, ENST00000490112, ENST00000492136, ENST00000496310
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2427 2280 1609 518 1441 360 4079 1744 3203 299 1427 1600 171 1204 2513 3
Low 12 711 117 106 510 105 277 453 530 120 33 13 4 1 275 2 2
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001128160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001128161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_014517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001740250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001740251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001740252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC093114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC122176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF198487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK027177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK309430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL133032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL831847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC047235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR749798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB131031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT584710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000283628   ⟹   ENSP00000283628
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl333,390,134 - 33,440,510 (-)Ensembl
RefSeq Acc Id: ENST00000283629   ⟹   ENSP00000283629
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl333,388,336 - 33,440,405 (-)Ensembl
RefSeq Acc Id: ENST00000411650   ⟹   ENSP00000393842
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl333,396,243 - 33,411,659 (-)Ensembl
RefSeq Acc Id: ENST00000447368   ⟹   ENSP00000395558
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl333,388,339 - 33,440,010 (-)Ensembl
RefSeq Acc Id: ENST00000456378   ⟹   ENSP00000401614
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl333,412,726 - 33,440,587 (-)Ensembl
RefSeq Acc Id: ENST00000464787
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl333,392,363 - 33,396,302 (-)Ensembl
RefSeq Acc Id: ENST00000466441
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl333,390,097 - 33,396,621 (-)Ensembl
RefSeq Acc Id: ENST00000467613
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl333,400,962 - 33,412,756 (-)Ensembl
RefSeq Acc Id: ENST00000481761
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl333,409,285 - 33,416,820 (-)Ensembl
RefSeq Acc Id: ENST00000486388
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl333,390,266 - 33,408,722 (-)Ensembl
RefSeq Acc Id: ENST00000490112
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl333,396,582 - 33,400,267 (-)Ensembl
RefSeq Acc Id: ENST00000492136
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl333,388,338 - 33,398,438 (-)Ensembl
RefSeq Acc Id: ENST00000496310
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl333,416,793 - 33,441,371 (-)Ensembl
RefSeq Acc Id: NM_001128160   ⟹   NP_001121632
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,388,336 - 33,440,405 (-)NCBI
GRCh37333,429,828 - 33,481,897 (-)RGD
Celera333,373,357 - 33,425,407 (-)RGD
HuRef333,370,390 - 33,422,369 (-)ENTREZGENE
CHM1_1333,379,810 - 33,431,829 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001128161   ⟹   NP_001121633
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,388,336 - 33,440,405 (-)NCBI
GRCh37333,429,828 - 33,481,897 (-)RGD
Celera333,373,357 - 33,425,407 (-)RGD
HuRef333,370,390 - 33,422,369 (-)ENTREZGENE
CHM1_1333,379,810 - 33,431,856 (-)NCBI
Sequence:
RefSeq Acc Id: NM_014517   ⟹   NP_055332
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,388,336 - 33,440,405 (-)NCBI
GRCh37333,429,828 - 33,481,897 (-)RGD
Build 36333,404,835 - 33,456,874 (-)NCBI Archive
Celera333,373,357 - 33,425,407 (-)RGD
HuRef333,370,390 - 33,422,369 (-)ENTREZGENE
CHM1_1333,379,810 - 33,431,829 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001740250
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,388,336 - 33,440,010 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001740251
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,396,188 - 33,440,040 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001740252
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,396,209 - 33,440,040 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001121633   ⟸   NM_001128161
- Peptide Label: isoform LBP-1b
- UniProtKB: Q9NZI7 (UniProtKB/Swiss-Prot),   A0A024R2L0 (UniProtKB/TrEMBL),   A8KAN5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001121632   ⟸   NM_001128160
- Peptide Label: isoform LBP-1a
- UniProtKB: Q9NZI7 (UniProtKB/Swiss-Prot),   A0A024R2J0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_055332   ⟸   NM_014517
- Peptide Label: isoform LBP-1b
- UniProtKB: Q9NZI7 (UniProtKB/Swiss-Prot),   A0A024R2L0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000393842   ⟸   ENST00000411650
RefSeq Acc Id: ENSP00000283629   ⟸   ENST00000283629
RefSeq Acc Id: ENSP00000283628   ⟸   ENST00000283628
RefSeq Acc Id: ENSP00000401614   ⟸   ENST00000456378
RefSeq Acc Id: ENSP00000395558   ⟸   ENST00000447368
Protein Domains
CP2   SAM_3

Promoters
RGD ID:6801861
Promoter ID:HG_KWN:44284
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:OTTHUMT00000342563,   OTTHUMT00000342564,   OTTHUMT00000342570
Position:
Human AssemblyChrPosition (strand)Source
Build 36333,414,916 - 33,415,416 (-)MPROMDB
RGD ID:6863922
Promoter ID:EPDNEW_H5126
Type:initiation region
Name:UBP1_1
Description:upstream binding protein 1 (LBP-1a)
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,440,378 - 33,440,438EPDNEW
RGD ID:6801860
Promoter ID:HG_KWN:44290
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001128160,   NM_014517,   OTTHUMT00000342562,   OTTHUMT00000342566,   OTTHUMT00000342571,   OTTHUMT00000342572
Position:
Human AssemblyChrPosition (strand)Source
Build 36333,456,266 - 33,457,627 (-)MPROMDB
RGD ID:6801859
Promoter ID:HG_KWN:44291
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   Lymphoblastoid
Transcripts:OTTHUMT00000342565
Position:
Human AssemblyChrPosition (strand)Source
Build 36333,458,214 - 33,458,714 (-)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3p22.3-22.2(chr3:32322382-36775606)x1 copy number loss See cases [RCV000051509] Chr3:32322382..36775606 [GRCh38]
Chr3:32363874..36817097 [GRCh37]
Chr3:32338878..36792101 [NCBI36]
Chr3:3p22.3-22.2
pathogenic
GRCh38/hg38 3p22.3-22.2(chr3:33062199-36829440)x1 copy number loss See cases [RCV000051510] Chr3:33062199..36829440 [GRCh38]
Chr3:33103691..36870931 [GRCh37]
Chr3:33078695..36845935 [NCBI36]
Chr3:3p22.3-22.2
pathogenic
GRCh38/hg38 3p26.3-22.2(chr3:52266-37148076)x3 copy number gain See cases [RCV000051097] Chr3:52266..37148076 [GRCh38]
Chr3:93949..37189567 [GRCh37]
Chr3:68949..37164571 [NCBI36]
Chr3:3p26.3-22.2
pathogenic
GRCh38/hg38 3p25.3-22.2(chr3:11463328-38919543)x3 copy number gain See cases [RCV000051720] Chr3:11463328..38919543 [GRCh38]
Chr3:11504802..38961034 [GRCh37]
Chr3:11479802..38936038 [NCBI36]
Chr3:3p25.3-22.2
pathogenic
GRCh38/hg38 3p26.3-22.1(chr3:53308-41381521)x3 copy number gain See cases [RCV000141810] Chr3:53308..41381521 [GRCh38]
Chr3:94991..41423012 [GRCh37]
Chr3:69991..41398016 [NCBI36]
Chr3:3p26.3-22.1
pathogenic
GRCh37/hg19 3p24.1-22.3(chr3:29689082-34233218)x1 copy number loss See cases [RCV000240426] Chr3:29689082..34233218 [GRCh37]
Chr3:3p24.1-22.3
pathogenic
GRCh37/hg19 3p26.3-22.2(chr3:61891-36710181)x3 copy number gain See cases [RCV000448528] Chr3:61891..36710181 [GRCh37]
Chr3:3p26.3-22.2
pathogenic
GRCh37/hg19 3p26.3-22.3(chr3:61891-33958201)x3 copy number gain See cases [RCV000510429] Chr3:61891..33958201 [GRCh37]
Chr3:3p26.3-22.3
pathogenic
GRCh37/hg19 3p26.3-22.2(chr3:61891-37459464)x3 copy number gain See cases [RCV000511463] Chr3:61891..37459464 [GRCh37]
Chr3:3p26.3-22.2
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p24.3-21.31(chr3:16923595-45249923)x2,3 copy number gain not provided [RCV000682249] Chr3:16923595..45249923 [GRCh37]
Chr3:3p24.3-21.31
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:12507 AgrOrtholog
COSMIC UBP1 COSMIC
Ensembl Genes ENSG00000153560 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000283628 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000283629 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000393842 UniProtKB/TrEMBL
  ENSP00000395558 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000401614 UniProtKB/TrEMBL
Ensembl Transcript ENST00000283628 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000283629 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000411650 UniProtKB/TrEMBL
  ENST00000447368 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000456378 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000153560 GTEx
HGNC ID HGNC:12507 ENTREZGENE
Human Proteome Map UBP1 Human Proteome Map
InterPro CP2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubp1_SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:7342 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 7342 ENTREZGENE
OMIM 609784 OMIM
Pfam CP2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA37154 PharmGKB
Superfamily-SCOP SSF47769 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A024R2J0 ENTREZGENE, UniProtKB/TrEMBL
  A0A024R2L0 ENTREZGENE
  A8KAN5 ENTREZGENE, UniProtKB/TrEMBL
  C9JWL3_HUMAN UniProtKB/TrEMBL
  F8WEP8_HUMAN UniProtKB/TrEMBL
  Q9NZI7 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q68CT0 UniProtKB/Swiss-Prot
  Q86Y57 UniProtKB/Swiss-Prot
  Q9H8V0 UniProtKB/Swiss-Prot
  Q9UD76 UniProtKB/Swiss-Prot
  Q9UD78 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-08 UBP1  upstream binding protein 1    upstream binding protein 1 (LBP-1a)  Symbol and/or name change 5135510 APPROVED