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Gene: MYO1A (myosin IA) Homo sapiens
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Symbol: MYO1A
Name: myosin IA
RGD ID: 1345169
Description: Predicted to have actin filament binding activity; actin-dependent ATPase activity; and microfilament motor activity. Involved in sensory perception of sound and vesicle localization. Localizes to several cellular components, including actin cytoskeleton; basolateral plasma membrane; and lateral plasma membrane. Implicated in autosomal dominant nonsyndromic deafness 48 and sensorineural hearing loss.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BBM-I; BBMI; brush border myosin I; brush border myosin-I; deafness, autosomal dominant 48; DFNA48; MIHC; MYHL; myosin I heavy chain; myosin, heavy polypeptide-like (100kD); myosin, heavy polypeptide-like 110kDa; myosin-Ia; unconventional myosin-Ia
Orthologs:
Mus musculus (house mouse) : Myo1a (myosin IA)  MGI  Alliance
Rattus norvegicus (Norway rat) : Myo1a (myosin IA)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myo1a (myosin IA)
Pan paniscus (bonobo/pygmy chimpanzee) : MYO1A (myosin IA)
Canis lupus familiaris (dog) : MYO1A (myosin IA)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myo1a (myosin IA)
Sus scrofa (pig) : MYO1A (myosin IA)
Chlorocebus sabaeus (African green monkey) : MYO1A (myosin IA)
Heterocephalus glaber (naked mole-rat) : Myo1a (myosin IA)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1257,028,517 - 57,051,198 (-)EnsemblGRCh38hg38GRCh38
GRCh381257,028,517 - 57,051,198 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371257,422,301 - 57,444,549 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361255,708,568 - 55,730,160 (-)NCBINCBI36hg18NCBI36
Build 341255,708,568 - 55,730,160NCBI
Celera1257,076,230 - 57,097,822 (-)NCBI
Cytogenetic Map12q13.3NCBI
HuRef1254,460,846 - 54,483,094 (-)NCBIHuRef
CHM1_11257,390,019 - 57,412,268 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MYO1A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1345169
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.