Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 2,6-dinitrotoluene | affects expression | ISO | Pcdhga2 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of PCDHGA2 mRNA | CTD | PMID:21346803 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PCDHGA2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of PCDHGA2 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of PCDHGA2 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Pcdhga2 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of PCDHGA2 exon | CTD | PMID:33297965 | 6-propyl-2-thiouracil | decreases expression | ISO | Pcdhga2 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of PCDHGA2 mRNA | CTD | PMID:30047161 | aflatoxin B1 | decreases methylation | EXP | | 6480464 | Aflatoxin B1 results in decreased methylation of PCDHGA2 gene | CTD | PMID:27153756 | amphetamine | decreases expression | ISO | Pcdhga2 (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of PCDHGA2 mRNA | CTD | PMID:30779732 | arsenite(3-) | increases methylation | EXP | | 6480464 | arsenite results in increased methylation of PCDHGA2 promoter | CTD | PMID:23974009 | benzatropine | decreases expression | EXP | | 6480464 | Benztropine results in decreased expression of PCDHGA2 protein | CTD | PMID:34122009 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of PCDHGA2 exon | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | Pcdhga2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of PCDHGA2 intron | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of PCDHGA2 5' UTR | CTD | PMID:27901495 | bisphenol A | decreases expression | ISO | Pcdhga2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of PCDHGA2 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PCDHGA2 mRNA | CTD | PMID:28628672 | cadmium dichloride | increases methylation | ISO | Pcdhga2 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in increased methylation of PCDHGA2 promoter | CTD | PMID:22457795 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PCDHGA2 gene] | CTD | PMID:28238834 | clobetasol | decreases expression | ISO | Pcdhga2 (Mus musculus) | 6480464 | Clobetasol results in decreased expression of PCDHGA2 mRNA | CTD | PMID:27462272 | dexamethasone | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PCDHGA2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of PCDHGA2 mRNA | CTD | PMID:28628672 | diallyl trisulfide | increases expression | EXP | | 6480464 | diallyl trisulfide results in increased expression of PCDHGA2 mRNA | CTD | PMID:34995734 | doxorubicin | affects methylation | ISO | Pcdhga2 (Rattus norvegicus) | 6480464 | Doxorubicin affects the methylation of PCDHGA2 gene | CTD | PMID:28962528 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of PCDHGA2 mRNA | CTD | PMID:29803840 | ethanol | increases expression | ISO | Pcdhga2 (Mus musculus) | 6480464 | Ethanol results in increased expression of PCDHGA2 mRNA | CTD | PMID:30319688 | indometacin | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PCDHGA2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of PCDHGA2 mRNA | CTD | PMID:28628672 | isoflurane | decreases methylation | ISO | Pcdhga2 (Mus musculus) | 6480464 | Isoflurane results in decreased methylation of PCDHGA2 mRNA | CTD | PMID:35249202 | methimazole | decreases expression | ISO | Pcdhga2 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of PCDHGA2 mRNA | CTD | PMID:30047161 | valproic acid | increases methylation | EXP | | 6480464 | Valproic Acid results in increased methylation of PCDHGA2 gene | CTD | PMID:29154799 | |