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Gene: ENOX2 (ecto-NOX disulfide-thiol exchanger 2) Homo sapiens
Symbol: ENOX2
Name: ecto-NOX disulfide-thiol exchanger 2
Description: Exhibits protein disulfide oxidoreductase activity. Involved in oxidation-reduction process and ultradian rhythm. Localizes to the external side of plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: APK1; APK1 antigen; COVA1; cytosolic ovarian carcinoma antigen 1; ecto-NADPH oxidase disulfide-thiol exchanger 2; tNOX; tumor-associated hydroquinone oxidase; tumor-associated NADH oxidase
Mus musculus (house mouse) : Enox2 (ecto-NOX disulfide-thiol exchanger 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Enox2 (ecto-NOX disulfide-thiol exchanger 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Enox2 (ecto-NOX disulfide-thiol exchanger 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ENOX2 (ecto-NOX disulfide-thiol exchanger 2)
Canis lupus familiaris (dog) : ENOX2 (ecto-NOX disulfide-thiol exchanger 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Enox2 (ecto-NOX disulfide-thiol exchanger 2)
Sus scrofa (pig) : ENOX2 (ecto-NOX disulfide-thiol exchanger 2)
Chlorocebus sabaeus (green monkey) : ENOX2 (ecto-NOX disulfide-thiol exchanger 2)
Heterocephalus glaber (naked mole-rat) : Enox2 (ecto-NOX disulfide-thiol exchanger 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX130,623,369 - 130,903,317 (-)Ensembl
GRCh38X130,622,330 - 130,903,317 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X129,757,355 - 130,037,219 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X129,585,036 - 129,864,889 (-)NCBINCBI36hg18NCBI36
Build 34X129,482,893 - 129,762,743NCBI
CeleraX130,143,767 - 130,423,625 (-)NCBI
Cytogenetic MapXq26.1NCBI
HuRefX119,152,711 - 119,430,022 (-)NCBIHuRef
CHM1_1X129,669,026 - 129,948,992 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ENOX2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1345108
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.