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Gene: RPA2 (replication protein A2) Homo sapiens
Symbol: RPA2
Name: replication protein A2
Description: Exhibits DNA binding activity and enzyme binding activity. Involved in several processes, including DNA metabolic process; mitotic G1 DNA damage checkpoint; and regulation of response to DNA damage stimulus. Localizes to the DNA replication factor A complex; PML body; and chromatin. Colocalizes with the chromosome, telomeric region and site of double-strand break.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: REPA2; replication factor A protein 2; replication protein A 32 kDa subunit; replication protein A 34 kDa subunit; replication protein A2, 32kDa; RF-A protein 2; RP-A p32; RP-A p34; RPA32
Mus musculus (house mouse) : Rpa2 (replication protein A2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rpa2 (replication protein A2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rpa2 (replication protein A2)
Pan paniscus (bonobo/pygmy chimpanzee) : RPA2 (replication protein A2)
Canis lupus familiaris (dog) : RPA2 (replication protein A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rpa2 (replication protein A2)
Sus scrofa (pig) : RPA2 (replication protein A2)
more info ...
Related Pseudogenes: RPA2P1   RPA2P2   RPA2P3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38127,891,524 - 27,914,797 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37128,218,035 - 28,241,255 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36128,090,636 - 28,113,823 (-)NCBINCBI36hg18NCBI36
Build 34127,902,191 - 27,925,378NCBI
Celera126,613,902 - 26,637,086 (-)NCBI
Cytogenetic Map1p35.3NCBI
HuRef126,473,870 - 26,497,363 (-)NCBIHuRef
CHM1_1128,333,534 - 28,356,808 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RPA2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1344829
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.