MED19 (mediator complex subunit 19) - Rat Genome Database

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Gene: MED19 (mediator complex subunit 19) Homo sapiens
Analyze
Symbol: MED19
Name: mediator complex subunit 19
RGD ID: 1344644
HGNC Page HGNC:29600
Description: Predicted to enable transcription coregulator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Located in core mediator complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: DT2P1G7; LCMR1; lung cancer metastasis-related protein 1; MED19AS; mediator of RNA polymerase II transcription subunit 19; mediator of RNA polymerase II transcription, subunit 19 homolog
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381157,703,709 - 57,712,215 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1157,703,710 - 57,712,221 (-)EnsemblGRCh38hg38GRCh38
GRCh371157,471,181 - 57,479,687 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361157,227,762 - 57,236,249 (-)NCBINCBI36Build 36hg18NCBI36
Build 341157,227,764 - 57,236,249NCBI
Celera1154,827,666 - 54,836,153 (-)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1153,820,108 - 53,828,597 (-)NCBIHuRef
CHM1_11157,338,056 - 57,346,544 (-)NCBICHM1_1
T2T-CHM13v2.01157,653,886 - 57,662,392 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. The Mediator complex and transcription regulation. Poss ZC, etal., Crit Rev Biochem Mol Biol. 2013 Nov-Dec;48(6):575-608. doi: 10.3109/10409238.2013.840259. Epub 2013 Oct 3.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:9417904   PMID:11559591   PMID:12584197   PMID:14576168   PMID:14638676   PMID:15175163   PMID:15989967   PMID:16169070   PMID:18029348   PMID:18854154   PMID:18976975   PMID:19049968  
PMID:20133760   PMID:20890603   PMID:21306606   PMID:21372827   PMID:21478038   PMID:21519921   PMID:21542455   PMID:21729782   PMID:21732059   PMID:21832049   PMID:21871180   PMID:21873635  
PMID:21988832   PMID:22531626   PMID:22565189   PMID:23076562   PMID:23098456   PMID:23276457   PMID:23322298   PMID:23563140   PMID:23705783   PMID:24565852   PMID:24882805   PMID:24981860  
PMID:25056061   PMID:25281560   PMID:25735376   PMID:26186194   PMID:26344197   PMID:27375018   PMID:27572702   PMID:27703004   PMID:27811858   PMID:28125713   PMID:28514442   PMID:28631286  
PMID:28765911   PMID:29511261   PMID:29568061   PMID:30161287   PMID:30463901   PMID:30554943   PMID:30583076   PMID:31365120   PMID:31527615   PMID:31586073   PMID:31715665   PMID:32296183  
PMID:32416067   PMID:32707033   PMID:33513133   PMID:33961781   PMID:34038190   PMID:35013556   PMID:35184651   PMID:35271311   PMID:35944360   PMID:36244648   PMID:36373674   PMID:37880276  


Genomics

Comparative Map Data
MED19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381157,703,709 - 57,712,215 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1157,703,710 - 57,712,221 (-)EnsemblGRCh38hg38GRCh38
GRCh371157,471,181 - 57,479,687 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361157,227,762 - 57,236,249 (-)NCBINCBI36Build 36hg18NCBI36
Build 341157,227,764 - 57,236,249NCBI
Celera1154,827,666 - 54,836,153 (-)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1153,820,108 - 53,828,597 (-)NCBIHuRef
CHM1_11157,338,056 - 57,346,544 (-)NCBICHM1_1
T2T-CHM13v2.01157,653,886 - 57,662,392 (-)NCBIT2T-CHM13v2.0
Med19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39284,508,769 - 84,519,330 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl284,508,746 - 84,518,559 (+)EnsemblGRCm39 Ensembl
GRCm38284,678,402 - 84,688,215 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl284,678,402 - 84,688,215 (+)EnsemblGRCm38mm10GRCm38
MGSCv37284,518,559 - 84,528,372 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36284,479,264 - 84,489,053 (+)NCBIMGSCv36mm8
Celera286,273,312 - 86,283,094 (+)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.45NCBI
Med19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8390,168,829 - 90,179,351 (+)NCBIGRCr8
mRatBN7.2369,762,138 - 69,772,661 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl369,762,166 - 69,772,036 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx373,143,945 - 73,154,449 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0381,742,608 - 81,753,112 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0379,501,528 - 79,512,043 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0372,080,630 - 72,091,150 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl372,080,630 - 72,091,150 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0378,601,276 - 78,611,797 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4367,887,927 - 67,898,448 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1367,784,342 - 67,793,007 (+)NCBI
Celera369,117,821 - 69,128,342 (+)NCBICelera
Cytogenetic Map3q24NCBI
Med19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555112,626,743 - 2,632,380 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555112,626,743 - 2,632,380 (-)NCBIChiLan1.0ChiLan1.0
MED19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2958,860,101 - 58,868,609 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11159,880,068 - 59,888,603 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01152,944,554 - 52,953,150 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11156,415,397 - 56,423,590 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1156,415,721 - 56,423,475 (-)Ensemblpanpan1.1panPan2
MED19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11838,490,536 - 38,497,508 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1838,490,714 - 38,496,314 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1838,037,440 - 38,044,468 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01839,172,355 - 39,179,359 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1839,171,784 - 39,179,359 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11838,755,552 - 38,762,544 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01838,328,706 - 38,335,709 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01838,959,241 - 38,966,242 (+)NCBIUU_Cfam_GSD_1.0
Med19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494714,717,279 - 14,723,916 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365814,831,231 - 4,837,695 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365814,830,872 - 4,837,583 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MED19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl213,241,455 - 13,250,820 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1213,241,311 - 13,250,821 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2212,874,165 - 12,884,010 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MED19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1115,515,874 - 15,524,663 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl115,515,814 - 15,525,085 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038112,866,829 - 112,875,285 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Med19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248643,021,178 - 3,025,877 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248643,014,489 - 3,027,784 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MED19
9 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11q12.1(chr11:57372226-57936167)x3 copy number gain See cases [RCV000051908] Chr11:57372226..57936167 [GRCh38]
Chr11:57139699..57703639 [GRCh37]
Chr11:56896275..57460215 [NCBI36]
Chr11:11q12.1		 uncertain significance
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3		 pathogenic
GRCh38/hg38 11q11-12.1(chr11:55319519-58998777)x3 copy number gain See cases [RCV000142757] Chr11:55319519..58998777 [GRCh38]
Chr11:55086995..58766250 [GRCh37]
Chr11:54843571..58522826 [NCBI36]
Chr11:11q11-12.1		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p11.12-q12.1(chr11:49313405-59008426)x3 copy number gain not provided [RCV000683370] Chr11:49313405..59008426 [GRCh37]
Chr11:11p11.12-q12.1		 uncertain significance
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11q12.1(chr11:57147016-57667222)x3 copy number gain not provided [RCV000750056] Chr11:57147016..57667222 [GRCh37]
Chr11:11q12.1		 benign
GRCh37/hg19 11q12.1(chr11:57306011-57669349)x3 copy number gain not provided [RCV000750057] Chr11:57306011..57669349 [GRCh37]
Chr11:11q12.1		 benign
Single allele duplication not provided [RCV000844966] Chr11:55033164..57518726 [GRCh37]
Chr11:11q11-12.1		 not provided
NM_001317078.4(MED19):c.-2C>T single nucleotide variant Intellectual disability [RCV001252069] Chr11:57712181 [GRCh38]
Chr11:57479653 [GRCh37]
Chr11:11q12.1		 likely benign
NC_000011.9:g.(?_57471510)_(57564464_?)del deletion not provided [RCV001387479] Chr11:57471510..57564464 [GRCh37]
Chr11:11q12.1		 pathogenic
GRCh37/hg19 11q12.1(chr11:57112299-57871866)x3 copy number gain not provided [RCV001825196] Chr11:57112299..57871866 [GRCh37]
Chr11:11q12.1		 not provided
GRCh37/hg19 11p11.2-q12.2(chr11:51581311-54891247)x3 copy number gain See cases [RCV002286338] Chr11:51581311..54891247 [GRCh37]
Chr11:11p11.2-q12.2		 pathogenic
NM_001317078.4(MED19):c.92C>G (p.Pro31Arg) single nucleotide variant Inborn genetic diseases [RCV003295457] Chr11:57712088 [GRCh38]
Chr11:57479560 [GRCh37]
Chr11:11q12.1		 uncertain significance
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 copy number gain MISSED ABORTION [RCV002282973] Chr11:32799481..134938470 [GRCh37]
Chr11:11p13-q25		 pathogenic
NM_001317078.4(MED19):c.548G>A (p.Arg183His) single nucleotide variant Inborn genetic diseases [RCV002968798] Chr11:57704742 [GRCh38]
Chr11:57472214 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_001317078.4(MED19):c.154C>T (p.Pro52Ser) single nucleotide variant Inborn genetic diseases [RCV002865666] Chr11:57712026 [GRCh38]
Chr11:57479498 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_001317078.4(MED19):c.568C>A (p.Pro190Thr) single nucleotide variant Inborn genetic diseases [RCV002798847] Chr11:57704722 [GRCh38]
Chr11:57472194 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_001317078.4(MED19):c.55A>G (p.Thr19Ala) single nucleotide variant Inborn genetic diseases [RCV002784739] Chr11:57712125 [GRCh38]
Chr11:57479597 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_001317078.4(MED19):c.472C>T (p.Pro158Ser) single nucleotide variant Inborn genetic diseases [RCV002652941] Chr11:57704975 [GRCh38]
Chr11:57472447 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_001317078.4(MED19):c.385T>G (p.Ser129Ala) single nucleotide variant Inborn genetic diseases [RCV003174263] Chr11:57705062 [GRCh38]
Chr11:57472534 [GRCh37]
Chr11:11q12.1		 uncertain significance
NM_001317078.4(MED19):c.522G>T (p.Lys174Asn) single nucleotide variant Inborn genetic diseases [RCV003199464] Chr11:57704768 [GRCh38]
Chr11:57472240 [GRCh37]
Chr11:11q12.1		 uncertain significance
GRCh37/hg19 11p11.12-q13.1(chr11:50398499-63924462)x3 copy number gain not specified [RCV003986918] Chr11:50398499..63924462 [GRCh37]
Chr11:11p11.12-q13.1		 likely pathogenic
GRCh37/hg19 11q12.1(chr11:57112299-57871866)x3 copy number gain not specified [RCV003986941] Chr11:57112299..57871866 [GRCh37]
Chr11:11q12.1		 uncertain significance
GRCh37/hg19 11q12.1-13.3(chr11:56895955-69295402)x3 copy number gain not specified [RCV003986944] Chr11:56895955..69295402 [GRCh37]
Chr11:11q12.1-13.3		 likely pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:975
Count of miRNA genes:499
Interacting mature miRNAs:544
Transcripts:ENST00000337672, ENST00000431606, ENST00000528205, ENST00000534677
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH80430  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371157,471,795 - 57,472,039UniSTSGRCh37
Build 361157,228,371 - 57,228,615RGDNCBI36
Celera1154,828,275 - 54,828,520RGD
Cytogenetic Map11q12.1UniSTS
HuRef1153,820,717 - 53,820,962UniSTS
GeneMap99-GB4 RH Map11199.98UniSTS
RH79721  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371157,472,209 - 57,472,601UniSTSGRCh37
Build 361157,228,785 - 57,229,177RGDNCBI36
Celera1154,828,689 - 54,829,081RGD
Cytogenetic Map11q12.1UniSTS
HuRef1153,821,131 - 53,821,524UniSTS
GeneMap99-GB4 RH Map11203.87UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1392 1067 1367 256 1056 119 3244 567 2618 313 1429 1462 152 1 1067 1732 5 2
Low 1047 1910 359 368 881 346 1113 1630 1116 106 31 151 22 137 1056 1
Below cutoff 14 14

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000337672   ⟹   ENSP00000337340
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1157,703,714 - 57,712,215 (-)Ensembl
RefSeq Acc Id: ENST00000431606   ⟹   ENSP00000416227
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1157,703,710 - 57,712,215 (-)Ensembl
RefSeq Acc Id: ENST00000528205
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1157,704,230 - 57,712,207 (-)Ensembl
RefSeq Acc Id: ENST00000534677
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1157,704,749 - 57,712,221 (-)Ensembl
RefSeq Acc Id: ENST00000645681   ⟹   ENSP00000493863
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1157,703,788 - 57,712,214 (-)Ensembl
RefSeq Acc Id: NM_001317078   ⟹   NP_001304007
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381157,703,710 - 57,712,215 (-)NCBI
CHM1_11157,338,051 - 57,346,666 (-)NCBI
T2T-CHM13v2.01157,653,887 - 57,662,392 (-)NCBI
Sequence:
RefSeq Acc Id: NM_153450   ⟹   NP_703151
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381157,703,710 - 57,712,215 (-)NCBI
GRCh371157,471,182 - 57,479,804 (-)NCBI
Build 361157,227,762 - 57,236,249 (-)NCBI Archive
Celera1154,827,666 - 54,836,153 (-)RGD
HuRef1153,820,108 - 53,828,597 (-)RGD
CHM1_11157,338,051 - 57,346,666 (-)NCBI
T2T-CHM13v2.01157,653,887 - 57,662,392 (-)NCBI
Sequence:
RefSeq Acc Id: NR_157587
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381157,703,709 - 57,712,215 (-)NCBI
T2T-CHM13v2.01157,653,886 - 57,662,392 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_703151   ⟸   NM_153450
- Peptide Label: isoform 2
- UniProtKB: I0J7B9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001304007   ⟸   NM_001317078
- Peptide Label: isoform 1
- UniProtKB: Q8IZD1 (UniProtKB/Swiss-Prot),   Q8IV02 (UniProtKB/Swiss-Prot),   A0JLT2 (UniProtKB/Swiss-Prot),   J3KR33 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000337340   ⟸   ENST00000337672
RefSeq Acc Id: ENSP00000416227   ⟸   ENST00000431606
RefSeq Acc Id: ENSP00000493863   ⟸   ENST00000645681

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0JLT2-F1-model_v2 AlphaFold A0JLT2 1-244 view protein structure

Promoters
RGD ID:6789489
Promoter ID:HG_KWN:12941
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000319399,   NM_001144012,   NM_015959,   NM_153450,   NR_026593,   UC001NLA.1,   UC001NLF.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361157,236,096 - 57,236,812 (+)MPROMDB
RGD ID:7220369
Promoter ID:EPDNEW_H15930
Type:initiation region
Name:MED19_1
Description:mediator complex subunit 19
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381157,712,215 - 57,712,275EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:29600 AgrOrtholog
COSMIC MED19 COSMIC
Ensembl Genes ENSG00000156603 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000337672 ENTREZGENE
  ENST00000337672.9 UniProtKB/Swiss-Prot
  ENST00000431606 ENTREZGENE
  ENST00000431606.5 UniProtKB/TrEMBL
  ENST00000645681.2 UniProtKB/Swiss-Prot
GTEx ENSG00000156603 GTEx
HGNC ID HGNC:29600 ENTREZGENE
Human Proteome Map MED19 Human Proteome Map
InterPro Mediator_Med19_met UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:219541 UniProtKB/Swiss-Prot
NCBI Gene 219541 ENTREZGENE
OMIM 612385 OMIM
PANTHER MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 19 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR22536 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Med19 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134926032 PharmGKB
UniProt A0JLT2 ENTREZGENE
  I0J7B9 ENTREZGENE, UniProtKB/TrEMBL
  J3KR33 ENTREZGENE, UniProtKB/TrEMBL
  MED19_HUMAN UniProtKB/Swiss-Prot
  Q8IV02 ENTREZGENE
  Q8IZD1 ENTREZGENE
UniProt Secondary Q8IV02 UniProtKB/Swiss-Prot
  Q8IZD1 UniProtKB/Swiss-Prot