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Gene: HOXD3 (homeobox D3) Homo sapiens
Symbol: HOXD3
Name: homeobox D3
Description: Exhibits RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in several processes, including Notch signaling pathway; positive regulation of transcription by RNA polymerase II; and transcription, DNA-templated. Localizes to the aggresome and nuclear body.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: homeo box D3; homeobox protein Hox-4A; homeobox protein Hox-D3; Hox-4.1; Hox-4.1, mouse, homolog of; HOX1D; HOX4; HOX4A; MGC10470
Mus musculus (house mouse) : Hoxd3 (homeobox D3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hoxd3 (homeo box D3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hoxd3 (homeobox D3)
Pan paniscus (bonobo/pygmy chimpanzee) : HOXD3 (homeobox D3)
Canis lupus familiaris (dog) : HOXD3 (homeobox D3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hoxd3 (homeobox D3)
Sus scrofa (pig) : HOXD3 (homeobox D3)
Chlorocebus sabaeus (African green monkey) : HOXD3 (homeobox D3)
Heterocephalus glaber (naked mole-rat) : Hoxd3 (homeobox D3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2176,136,612 - 176,173,102 (+)Ensembl
GRCh382176,157,307 - 176,173,102 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372177,001,669 - 177,043,737 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362176,737,051 - 176,746,072 (+)NCBINCBI36hg18NCBI36
Build 342176,854,311 - 176,863,333NCBI
Celera2170,637,984 - 170,647,006 (+)NCBI
Cytogenetic Map2q31.1NCBI
HuRef2168,905,653 - 168,914,773 (+)NCBIHuRef
CHM1_12177,034,674 - 177,043,694 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on HOXD3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1344554
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.