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Gene: PPP1R17 (protein phosphatase 1 regulatory subunit 17) Homo sapiens
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Symbol: PPP1R17
Name: protein phosphatase 1 regulatory subunit 17
Description: The protein encoded by this gene is found primarily in cerebellar Purkinje cells, where it functions as a protein phosphatase inhibitor. The encoded protein is a substrate for cGMP-dependent protein kinase. An allele of this gene was discovered that increases susceptibility to hypercholesterolemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C7orf16; G-substrate; GSBS
Orthologs:
Mus musculus (house mouse) : Ppp1r17 (protein phosphatase 1, regulatory subunit 17)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ppp1r17 (protein phosphatase 1, regulatory subunit 17)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppp1r17 (protein phosphatase 1 regulatory subunit 17)
Pan paniscus (bonobo/pygmy chimpanzee) : PPP1R17 (protein phosphatase 1 regulatory subunit 17)
Canis lupus familiaris (dog) : PPP1R17 (protein phosphatase 1 regulatory subunit 17)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppp1r17 (protein phosphatase 1 regulatory subunit 17)
Sus scrofa (pig) : PPP1R17 (protein phosphatase 1 regulatory subunit 17)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38731,687,017 - 31,710,158 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37731,726,631 - 31,748,069 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36731,693,372 - 31,714,594 (+)NCBINCBI36hg18NCBI36
Build 34731,500,086 - 31,521,308NCBI
Celera731,713,567 - 31,735,005 (+)NCBI
Cytogenetic Map7p14.3NCBI
HuRef731,607,435 - 31,628,784 (+)NCBIHuRef
CHM1_1731,726,232 - 31,747,670 (+)NCBICHM1_1
CRA_TCAGchr7v2731,774,930 - 31,796,368 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PPP1R17
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1344493
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.