ANXA2P3 (annexin A2 pseudogene 3)

Gene: ANXA2P3 (annexin A2 pseudogene 3) Homo sapiens

Analyze

Symbol:

ANXA2P3

Name:

annexin A2 pseudogene 3

RGD ID:

1344486

HGNC Page

HGNC:540

Description:

INTERACTS WITH 17beta-estradiol; 3-isobutyl-1-methyl-7H-xanthine; arsenous acid

Type:

pseudo (Ensembl: processed_pseudogene)

RefSeq Status:

PROVISIONAL

Previously known as:

ANX2L3; ANX2P3; LIP2; LPC2C

Related Functional Gene:

ANXA2

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	64,825,528 - 64,826,877 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	64,825,572 - 64,826,579 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	66,585,285 - 66,586,634 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	66,255,291 - 66,256,640 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	66,255,348 - 66,256,640	NCBI
Celera	10	59,854,487 - 59,855,837 (+)	NCBI		Celera
Cytogenetic Map	10	q21.3	NCBI
HuRef	10	60,577,348 - 60,578,698 (+)	NCBI		HuRef
CHM1_1	10	66,867,284 - 66,868,633 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	65,683,446 - 65,684,796 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
17beta-estradiol	multiple interactions	EXP		6480464	[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ANXA2P3 mRNA	CTD	PMID:20823114
3-isobutyl-1-methyl-7H-xanthine	multiple interactions	EXP		6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ANXA2P3 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ANXA2P3 mRNA	CTD	PMID:28628672
arsenous acid	decreases response to substance	EXP		6480464	ANXA2P3 protein results in decreased susceptibility to Arsenic Trioxide	CTD	PMID:20707922
bisphenol A	multiple interactions	EXP		6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ANXA2P3 mRNA	CTD	PMID:28628672
bisphenol F	multiple interactions	EXP		6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ANXA2P3 mRNA	CTD	PMID:28628672
bucladesine	multiple interactions	EXP		6480464	[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ANXA2P3 mRNA	CTD	PMID:20823114
butan-1-ol	multiple interactions	EXP		6480464	[[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of ANXA2P3 mRNA	CTD	PMID:29432896
cyclosporin A	decreases expression	EXP		6480464	Cyclosporine results in decreased expression of ANXA2P3 mRNA	CTD	PMID:22147139
dexamethasone	multiple interactions	EXP		6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ANXA2P3 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ANXA2P3 mRNA	CTD	PMID:28628672
diarsenic trioxide	decreases response to substance	EXP		6480464	ANXA2P3 protein results in decreased susceptibility to Arsenic Trioxide	CTD	PMID:20707922
dorsomorphin	multiple interactions	EXP		6480464	[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ...	CTD	PMID:27188386
indometacin	multiple interactions	EXP		6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ANXA2P3 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ANXA2P3 mRNA	CTD	PMID:28628672
medroxyprogesterone acetate	multiple interactions	EXP		6480464	[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ANXA2P3 mRNA	CTD	PMID:20823114
mercury dibromide	increases expression	EXP		6480464	mercuric bromide results in increased expression of ANXA2P3 mRNA	CTD	PMID:26272509
mercury dibromide	multiple interactions	EXP		6480464	[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA2P3 mRNA	CTD	PMID:27188386
panobinostat	increases expression	EXP		6480464	panobinostat results in increased expression of ANXA2P3 mRNA	CTD	PMID:26272509
panobinostat	multiple interactions	EXP		6480464	[NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA2P3 mRNA	CTD	PMID:27188386
phenylmercury acetate	increases expression	EXP		6480464	Phenylmercuric Acetate results in increased expression of ANXA2P3 mRNA	CTD	PMID:26272509
phenylmercury acetate	multiple interactions	EXP		6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA2P3 mRNA	CTD	PMID:27188386
SB 431542	multiple interactions	EXP		6480464	[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ...	CTD	PMID:27188386
silicon dioxide	increases expression	EXP		6480464	Silicon Dioxide results in increased expression of ANXA2P3 mRNA	CTD	PMID:25351596
trichostatin A	increases expression	EXP		6480464	trichostatin A results in increased expression of ANXA2P3 mRNA	CTD	PMID:24935251 and PMID:26272509
trichostatin A	multiple interactions	EXP		6480464	[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA2P3 mRNA	CTD	PMID:27188386
valproic acid	increases expression	EXP		6480464	Valproic Acid results in increased expression of ANXA2P3 mRNA	CTD	PMID:19101580 more ...
valproic acid	multiple interactions	EXP		6480464	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA2P3 mRNA	CTD	PMID:27188386

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (EXP)

3-isobutyl-1-methyl-7H-xanthine (EXP)

arsenous acid (EXP)

bisphenol A (EXP)

bisphenol F (EXP)

bucladesine (EXP)

butan-1-ol (EXP)

cyclosporin A (EXP)

dexamethasone (EXP)

diarsenic trioxide (EXP)

dorsomorphin (EXP)

indometacin (EXP)

medroxyprogesterone acetate (EXP)

mercury dibromide (EXP)

panobinostat (EXP)

phenylmercury acetate (EXP)

SB 431542 (EXP)

silicon dioxide (EXP)

trichostatin A (EXP)

valproic acid (EXP)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:2174397	PMID:20339536	PMID:30569159

Genomics

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	213
Count of miRNA genes:	207
Interacting mature miRNAs:	212
Transcripts:	ENST00000404883
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

adipose tissue

appendage

High

Medium

Low

384

Below cutoff

690

974

468

147

316

2001

563

1756

521

661

619

1220

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NR_001446	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC069020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M62895	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000404883

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	10	64,825,572 - 64,826,579 (+)	Ensembl

RefSeq Acc Id:

NR_001446

RefSeq Status:

PROVISIONAL

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	10	64,825,528 - 64,826,877 (+)	NCBI
GRCh37	10	66,585,285 - 66,586,634 (+)	RGD
Build 36	10	66,255,291 - 66,256,640 (+)	NCBI Archive
Celera	10	59,854,487 - 59,855,837 (+)	RGD
HuRef	10	60,577,348 - 60,578,698 (+)	RGD
CHM1_1	10	66,867,284 - 66,868,633 (+)	NCBI
T2T-CHM13v2.0	10	65,683,446 - 65,684,796 (+)	NCBI

Sequence:

show sequence

GGGGACGCTCTCAGCTCTCAGTGCCTGGCCCAGCTTCCTTCAAAATGTATACTATTTACGAAAT
CCTGTGCAAGCTCAGCTTGGAGGGTCATCACTCTACACCCTCAGGTGCATATGGGTCAGTCAAA
GCCTACACCAACTTTGATGCTGAGGGGGATGCTTTGAACATTGAAAGGACCATCAGGACAAAAG
GTGTGGGTAAGTTCACCATTGTCAACATTTTGACCAACAGCAGGAATGCTCGGAGAGAGGATGT
TGCCTTTGCCTAGCAGAGAAGGACCACAAAGGAACTTACATCAGCACTGAAGTCAGCCTTACTG
GCCACCTGGAGACAGTCATTTTGGGCCTATTGAAGACACCTGCTCAGTATGATGCTTCTGAGCT
AAAAGCTTCCATGAAGGGGCTGGGAACTGAGGAGGACTCCCTCGTTGAGATCATCTGCTCAACA
ACCAACCAGGAGCTCCAGGAAATTAACAGAGTCTACAAAGAAATGTACAAAACTGATCTGGAGA
AGGACATTATTTCGGACACATATGGTGACTTCTGCAAGCTGATGTTTGCCCTGGCAAATGTTAG
AAGACCAGAGGATGGCTCTGTCGTTGATTATGAACTGATTGACCAAGATGCCCGGGATTTCTGT
GATGCTGGAGTGAAGAGGAAAAGAACTGATGTTCCCAAGTGGATCAGCATGATGACCGAGTAGA
GCATGTCCCACCTCCAGAAAGTATTTGATAGGTACAAGAGCTACAGCCCATCAAGAGAGAGCAT
CAAGAAAGAGGTTAAAGGAGACCTGGAAAATGCTTTCCTGAACCTGGTCCAGTGCATTCAGAAC
AAGCCCCTGTATTTTGCTGATTGGCTGTACTACTCCATGAAGGGCCGGGGGCTCGAGATAAGGT
CCTGATCAGAATCATCGTCTCCCGCAGTGAAGTGGACATGTTGAAAATTAGGTCTGAATTCAAG
AGAAAGTATGGCATGTCCCCGTACTATTACATCCAGCAAGACACTAAGAACGACTACCCAAAAA
GCACTGCTGTACCTGTGTGGTGGAGATGACTGAAGCCCAACATAGCTTGAGCTTCCAGAAACGG
TGCTCCCCACGCTTCCAGCTAACAGGTCTAGAAAACCAGCTTGTGGCTAACAGTCCCTGTGGCC
GTCCCTGTGAAGATGACATTAGCATTGCCCCCAACCTCATTTTAGTTGCGTAAGCATAGCCTGG
CTTTCCTGTCTAGTCTCTCCTGTAAGCCAAAGAAATGTACATTCCAAGCAGTTGGAAGTGAAAT
CTATGATGTGAAACACTTTGCCTCCTGTGTACTGTGTCATAAACAGATGAATAAACTGAATTTG
TACTTT

hide sequence

Additional Information

External Database Links

Database	Acc Id	Source(s)
COSMIC	ANXA2P3	COSMIC
Ensembl Genes	ENSG00000216740	Ensembl
GTEx	ENSG00000216740	GTEx
HGNC ID	HGNC:540	ENTREZGENE
Human Proteome Map	ANXA2P3	Human Proteome Map
NCBI Gene	305	ENTREZGENE
PharmGKB	PA24830	PharmGKB

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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