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Gene: G6PC2 (glucose-6-phosphatase catalytic subunit 2) Homo sapiens
Symbol: G6PC2
Name: glucose-6-phosphatase catalytic subunit 2
Description: Exhibits glucose-6-phosphatase activity. Involved in glucose homeostasis and regulation of insulin secretion. Predicted to localize to the endoplasmic reticulum membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: G-6-Pase 2; G6Pase 2; glucose-6-phosphatase 2; glucose-6-phosphatase, catalytic, 2; IGRP; islet-specific G6CP-related protein; islet-specific glucose-6-phosphatase catalytic subunit-related protein; islet-specific glucose-6-phosphatase-related protein; MGC141936
Mus musculus (house mouse) : G6pc2 (glucose-6-phosphatase, catalytic, 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : G6pc2 (glucose-6-phosphatase catalytic subunit 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : G6pc2 (glucose-6-phosphatase catalytic subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : G6PC2 (glucose-6-phosphatase catalytic subunit 2)
Canis lupus familiaris (dog) : G6PC2 (glucose-6-phosphatase catalytic subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : G6pc2 (glucose-6-phosphatase catalytic subunit 2)
Sus scrofa (pig) : G6PC2 (glucose-6-phosphatase catalytic subunit 2)
Chlorocebus sabaeus (green monkey) : G6PC2 (glucose-6-phosphatase catalytic subunit 2)
Heterocephalus glaber (naked mole-rat) : G6pc2 (glucose-6-phosphatase catalytic subunit 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2168,901,291 - 168,910,000 (+)Ensembl
GRCh382168,901,223 - 168,910,000 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372169,757,750 - 169,766,510 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362169,465,996 - 169,474,756 (+)NCBINCBI36hg18NCBI36
Build 342169,583,348 - 169,590,096NCBI
Celera2163,383,072 - 163,391,831 (+)NCBI
Cytogenetic Map2q31.1NCBI
HuRef2161,653,943 - 161,663,046 (+)NCBIHuRef
CHM1_12169,763,602 - 169,772,361 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on G6PC2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1344189
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.