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Gene: TTC21B (tetratricopeptide repeat domain 21B) Homo sapiens
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Symbol: TTC21B
Name: tetratricopeptide repeat domain 21B
Description: Involved in protein localization to cilium; regulation of intraciliary retrograde transport; and regulation of transcription by RNA polymerase II. Localizes to the intraciliary transport particle A. Implicated in asphyxiating thoracic dystrophy 4 and nephronophthisis 12.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATD4; FAP60; FLA17; FLJ11457; IFT139; IFT139B; intraflagellar transport 139 homolog; JBTS11; Nbla10696; NPHP12; putative protein product of Nbla10696; SRTD4; tetratricopeptide repeat protein 21B; THM1; TPR repeat protein 21B
Orthologs:
Mus musculus (house mouse) : Ttc21b (tetratricopeptide repeat domain 21B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ttc21b (tetratricopeptide repeat domain 21B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ttc21b (tetratricopeptide repeat domain 21B)
Pan paniscus (bonobo/pygmy chimpanzee) : TTC21B (tetratricopeptide repeat domain 21B)
Canis lupus familiaris (dog) : TTC21B (tetratricopeptide repeat domain 21B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ttc21b (tetratricopeptide repeat domain 21B)
Sus scrofa (pig) : TTC21B (tetratricopeptide repeat domain 21B)
Chlorocebus sabaeus (green monkey) : TTC21B (tetratricopeptide repeat domain 21B)
Heterocephalus glaber (naked mole-rat) : Ttc21b (tetratricopeptide repeat domain 21B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2165,857,475 - 165,953,816 (-)Ensembl
GRCh382165,873,362 - 165,953,781 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372166,729,872 - 166,810,348 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362166,438,699 - 166,518,594 (-)NCBINCBI36hg18NCBI36
Build 342166,556,350 - 166,635,855NCBI
Celera2160,340,419 - 160,420,342 (-)NCBI
Cytogenetic Map2q24.3NCBI
HuRef2158,611,801 - 158,691,750 (-)NCBIHuRef
CHM1_12166,736,157 - 166,816,658 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on TTC21B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1344161
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-02-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.