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Gene: IGLL1 (immunoglobulin lambda like polypeptide 1) Homo sapiens
Symbol: IGLL1
Name: immunoglobulin lambda like polypeptide 1
Description: Predicted to have antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. Predicted to localize to external side of plasma membrane and immunoglobulin complex, circulating. Implicated in agammaglobulinemia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 14.1; AGM2; CD179 antigen-like family member B; CD179b; CD179b antigen; ig lambda-5; IGL1; IGL5; IGLJ14.1; IGLL; IGO; IGVPB; immunoglobulin lambda-like polypeptide 1; immunoglobulin omega polypeptide chain; immunoglobulin-related 14.1 protein; immunoglobulin-related protein 14.1; lambda5; Pre-B lymphocyte-specific protein-2; VPREB2
Related Pseudogenes: IGLC4   IGLJCOR18   IGLL3P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2223,573,125 - 23,580,302 (-)EnsemblGRCh38hg38GRCh38
GRCh382223,573,125 - 23,580,290 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372223,915,312 - 23,922,619 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,245,312 - 22,252,495 (-)NCBINCBI36hg18NCBI36
Build 342222,239,865 - 22,247,049NCBI
Celera227,754,682 - 7,761,865 (-)NCBI
Cytogenetic Map22q11.23NCBI
HuRef226,904,730 - 6,911,914 (-)NCBIHuRef
CHM1_12223,927,473 - 23,934,655 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IGLL1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1344157
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.