SLC35A5 (solute carrier family 35 member A5) - Rat Genome Database

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Gene: SLC35A5 (solute carrier family 35 member A5) Homo sapiens
Analyze
Symbol: SLC35A5
Name: solute carrier family 35 member A5
RGD ID: 1344135
HGNC Page HGNC
Description: Predicted to enable pyrimidine nucleotide-sugar transmembrane transporter activity. Predicted to be involved in carbohydrate transport and pyrimidine nucleotide-sugar transmembrane transport. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be integral component of Golgi membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: DKFZp434E102; FLJ11130; FLJ20730; FLJ25973; probable UDP-sugar transporter protein SLC35A5; solute carrier family 35, member A5
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383112,561,320 - 112,585,579 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3112,561,709 - 112,585,579 (+)EnsemblGRCh38hg38GRCh38
GRCh373112,280,167 - 112,304,426 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363113,763,585 - 113,785,693 (+)NCBINCBI36hg18NCBI36
Build 343113,763,584 - 113,785,692NCBI
Celera3110,689,568 - 110,711,683 (+)NCBI
Cytogenetic Map3q13.2NCBI
HuRef3109,664,922 - 109,686,677 (+)NCBIHuRef
CHM1_13112,244,788 - 112,267,218 (+)NCBICHM1_1
T2T-CHM13v2.03115,282,355 - 115,306,614 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients. Xiong Y, etal., Emerg Microbes Infect. 2020 Dec;9(1):761-770. doi: 10.1080/22221751.2020.1747363.
Additional References at PubMed
PMID:12477932   PMID:12759756   PMID:12975309   PMID:14702039   PMID:16344560   PMID:17207965   PMID:19164095   PMID:21186191   PMID:21873635   PMID:25210595   PMID:26186194   PMID:28514442  
PMID:30021884   PMID:30641943   PMID:31741433   PMID:31862882   PMID:32296183   PMID:32393512   PMID:33961781   PMID:35271311  


Genomics

Comparative Map Data
SLC35A5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383112,561,320 - 112,585,579 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3112,561,709 - 112,585,579 (+)EnsemblGRCh38hg38GRCh38
GRCh373112,280,167 - 112,304,426 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363113,763,585 - 113,785,693 (+)NCBINCBI36hg18NCBI36
Build 343113,763,584 - 113,785,692NCBI
Celera3110,689,568 - 110,711,683 (+)NCBI
Cytogenetic Map3q13.2NCBI
HuRef3109,664,922 - 109,686,677 (+)NCBIHuRef
CHM1_13112,244,788 - 112,267,218 (+)NCBICHM1_1
T2T-CHM13v2.03115,282,355 - 115,306,614 (+)NCBI
Slc35a5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391644,959,936 - 44,979,036 (-)NCBIGRCm39mm39
GRCm39 Ensembl1644,959,936 - 44,979,069 (-)Ensembl
GRCm381645,139,573 - 45,158,673 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1645,139,573 - 45,158,706 (-)EnsemblGRCm38mm10GRCm38
MGSCv371645,139,686 - 45,158,786 (-)NCBIGRCm37mm9NCBIm37
MGSCv361645,058,905 - 45,077,971 (-)NCBImm8
Celera1645,532,900 - 45,552,193 (-)NCBICelera
Cytogenetic Map16B5NCBI
cM Map1629.44NCBI
Slc35a5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21155,653,376 - 55,674,476 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1155,653,394 - 55,674,473 (+)Ensembl
Rnor_6.01160,613,865 - 60,634,849 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1160,613,882 - 60,634,851 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01164,716,008 - 64,737,004 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41157,190,760 - 57,211,083 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1155,219,430 - 55,239,646 (+)NCBICelera
Cytogenetic Map11q21NCBI
Slc35a5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542712,906,632 - 12,940,419 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542712,906,650 - 12,940,419 (+)NCBIChiLan1.0ChiLan1.0
SLC35A5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13116,634,496 - 116,659,499 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3116,635,256 - 116,656,956 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03109,710,151 - 109,732,678 (+)NCBIMhudiblu_PPA_v0panPan3
SLC35A5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13317,073,378 - 17,109,178 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3317,073,678 - 17,093,017 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3317,176,529 - 17,212,511 (+)NCBI
ROS_Cfam_1.03317,317,159 - 17,353,199 (+)NCBI
ROS_Cfam_1.0 Ensembl3317,309,962 - 17,347,545 (+)Ensembl
UMICH_Zoey_3.13317,122,002 - 17,157,975 (+)NCBI
UNSW_CanFamBas_1.03317,169,439 - 17,205,397 (+)NCBI
UU_Cfam_GSD_1.03317,719,018 - 17,754,993 (+)NCBI
Slc35a5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602137,241,638 - 137,263,601 (-)NCBI
SpeTri2.0NW_004936536258,288 - 280,280 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC35A5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13147,251,896 - 147,279,300 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113147,252,702 - 147,279,386 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213156,836,045 - 156,876,778 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC35A5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12268,205,783 - 68,227,717 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2268,208,604 - 68,226,340 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604198,234,633 - 98,255,334 (+)NCBIVero_WHO_p1.0
Slc35a5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473135,944,545 - 35,978,450 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462473135,944,545 - 35,978,470 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
SLC35A5_8059  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373112,302,382 - 112,303,092UniSTSGRCh37
Build 363113,785,072 - 113,785,782RGDNCBI36
Celera3110,711,062 - 110,711,772RGD
HuRef3109,685,773 - 109,686,483UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1996
Count of miRNA genes:933
Interacting mature miRNAs:1093
Transcripts:ENST00000261034, ENST00000460615, ENST00000460713, ENST00000468642, ENST00000484995, ENST00000492406, ENST00000494706
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1135 1353 1222 217 1115 130 2115 483 2686 291 1294 1382 100 844 1281 4
Low 1304 1620 504 407 819 335 2242 1713 1048 128 166 231 74 1 360 1507 2 2
Below cutoff 18 17 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_052994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001348905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001348906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001348907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001348908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001348909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001348910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001348911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_017945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB075484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC048334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC092692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK000737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK001992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK098839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL117531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY358994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA854399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000261034   ⟹   ENSP00000261034
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3112,562,072 - 112,584,156 (+)Ensembl
RefSeq Acc Id: ENST00000460615
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3112,570,439 - 112,580,756 (+)Ensembl
RefSeq Acc Id: ENST00000460713
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3112,563,461 - 112,583,152 (+)Ensembl
RefSeq Acc Id: ENST00000468642   ⟹   ENSP00000418265
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3112,562,037 - 112,570,574 (+)Ensembl
RefSeq Acc Id: ENST00000484995   ⟹   ENSP00000419958
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3112,561,709 - 112,580,559 (+)Ensembl
RefSeq Acc Id: ENST00000492406   ⟹   ENSP00000417654
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3112,562,045 - 112,585,579 (+)Ensembl
RefSeq Acc Id: ENST00000494706   ⟹   ENSP00000420398
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl3112,564,128 - 112,582,730 (+)Ensembl
RefSeq Acc Id: NM_001348905   ⟹   NP_001335834
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383112,561,680 - 112,585,579 (+)NCBI
T2T-CHM13v2.03115,282,715 - 115,306,614 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001348906   ⟹   NP_001335835
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383112,561,320 - 112,585,579 (+)NCBI
T2T-CHM13v2.03115,282,355 - 115,306,614 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001348907   ⟹   NP_001335836
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383112,562,045 - 112,585,579 (+)NCBI
T2T-CHM13v2.03115,283,080 - 115,306,614 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001348908   ⟹   NP_001335837
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383112,562,045 - 112,585,579 (+)NCBI
T2T-CHM13v2.03115,283,080 - 115,306,614 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001348909   ⟹   NP_001335838
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383112,562,045 - 112,585,579 (+)NCBI
T2T-CHM13v2.03115,283,080 - 115,306,614 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001348910   ⟹   NP_001335839
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383112,562,045 - 112,585,579 (+)NCBI
T2T-CHM13v2.03115,283,080 - 115,306,614 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001348911   ⟹   NP_001335840
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383112,562,045 - 112,585,579 (+)NCBI
T2T-CHM13v2.03115,283,080 - 115,306,614 (+)NCBI
Sequence:
RefSeq Acc Id: NM_017945   ⟹   NP_060415
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383112,562,045 - 112,585,579 (+)NCBI
GRCh373112,280,857 - 112,303,286 (+)NCBI
Build 363113,763,585 - 113,785,693 (+)NCBI Archive
Celera3110,689,568 - 110,711,683 (+)RGD
HuRef3109,664,922 - 109,686,677 (+)NCBI
CHM1_13112,244,788 - 112,267,218 (+)NCBI
T2T-CHM13v2.03115,283,080 - 115,306,614 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_060415   ⟸   NM_017945
- Peptide Label: isoform 1
- UniProtKB: Q9BS91 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001335835   ⟸   NM_001348906
- Peptide Label: isoform 1
- Sequence:
RefSeq Acc Id: NP_001335834   ⟸   NM_001348905
- Peptide Label: isoform 1
- Sequence:
RefSeq Acc Id: NP_001335839   ⟸   NM_001348910
- Peptide Label: isoform 4
- Sequence:
RefSeq Acc Id: NP_001335840   ⟸   NM_001348911
- Peptide Label: isoform 5
- Sequence:
RefSeq Acc Id: NP_001335838   ⟸   NM_001348909
- Peptide Label: isoform 3
- Sequence:
RefSeq Acc Id: NP_001335837   ⟸   NM_001348908
- Peptide Label: isoform 2
- Sequence:
RefSeq Acc Id: NP_001335836   ⟸   NM_001348907
- Peptide Label: isoform 1
- Sequence:
RefSeq Acc Id: ENSP00000417654   ⟸   ENST00000492406
RefSeq Acc Id: ENSP00000418265   ⟸   ENST00000468642
RefSeq Acc Id: ENSP00000420398   ⟸   ENST00000494706
RefSeq Acc Id: ENSP00000419958   ⟸   ENST00000484995
RefSeq Acc Id: ENSP00000261034   ⟸   ENST00000261034

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9BS91-F1-model_v2 AlphaFold Q9BS91 1-424 view protein structure

Promoters
RGD ID:6865244
Promoter ID:EPDNEW_H5787
Type:initiation region
Name:SLC35A5_2
Description:solute carrier family 35 member A5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H5789  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh383112,561,709 - 112,561,769EPDNEW
RGD ID:6865248
Promoter ID:EPDNEW_H5789
Type:initiation region
Name:SLC35A5_1
Description:solute carrier family 35 member A5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H5787  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh383112,562,048 - 112,562,108EPDNEW
RGD ID:6800936
Promoter ID:HG_KWN:45836
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000283290,   ENST00000402314,   NM_017945,   UC010HQE.1
Position:
Human AssemblyChrPosition (strand)Source
Build 363113,762,831 - 113,763,957 (-)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3q13.2-13.31(chr3:112168829-117393356)x1 copy number loss See cases [RCV000050766] Chr3:112168829..117393356 [GRCh38]
Chr3:111887676..117112203 [GRCh37]
Chr3:113370366..118594893 [NCBI36]
Chr3:3q13.2-13.31		 pathogenic
GRCh38/hg38 3q11.1-21.1(chr3:93886671-123216683)x1 copy number loss See cases [RCV000051543] Chr3:93886671..123216683 [GRCh38]
Chr3:93605515..122935530 [GRCh37]
Chr3:95088205..124418220 [NCBI36]
Chr3:3q11.1-21.1		 pathogenic
GRCh38/hg38 3q13.13-13.31(chr3:108242572-116169331)x1 copy number loss See cases [RCV000051544] Chr3:108242572..116169331 [GRCh38]
Chr3:107961419..115888178 [GRCh37]
Chr3:109444109..117370868 [NCBI36]
Chr3:3q13.13-13.31		 pathogenic
GRCh38/hg38 3q13.2-13.31(chr3:112479482-115774102)x1 copy number loss See cases [RCV000051545] Chr3:112479482..115774102 [GRCh38]
Chr3:112198329..115492949 [GRCh37]
Chr3:113681019..116975639 [NCBI36]
Chr3:3q13.2-13.31		 pathogenic
GRCh38/hg38 3q13.11-13.31(chr3:104621220-116093884)x3 copy number gain See cases [RCV000051722] Chr3:104621220..116093884 [GRCh38]
Chr3:104340064..115812731 [GRCh37]
Chr3:105822754..117295421 [NCBI36]
Chr3:3q13.11-13.31		 pathogenic
GRCh38/hg38 3q11.1-13.31(chr3:93819623-116887056)x1 copy number loss See cases [RCV000135320] Chr3:93819623..116887056 [GRCh38]
Chr3:93538467..116605903 [GRCh37]
Chr3:95021157..118088593 [NCBI36]
Chr3:3q11.1-13.31		 pathogenic
GRCh38/hg38 3q13.11-29(chr3:103426882-198110178)x3 copy number gain See cases [RCV000134948] Chr3:103426882..198110178 [GRCh38]
Chr3:103145726..197837049 [GRCh37]
Chr3:104628416..199321446 [NCBI36]
Chr3:3q13.11-29		 pathogenic
GRCh38/hg38 3q13.2-13.31(chr3:112465096-115774102)x1 copy number loss See cases [RCV000135592] Chr3:112465096..115774102 [GRCh38]
Chr3:112183943..115492949 [GRCh37]
Chr3:113666633..116975639 [NCBI36]
Chr3:3q13.2-13.31		 likely pathogenic
GRCh38/hg38 3q11.2-13.31(chr3:97795369-115663349)x1 copy number loss See cases [RCV000138186] Chr3:97795369..115663349 [GRCh38]
Chr3:97514213..115382196 [GRCh37]
Chr3:98996903..116864886 [NCBI36]
Chr3:3q11.2-13.31		 pathogenic|uncertain significance
GRCh38/hg38 3q13.2-13.31(chr3:112465094-115774111)x1 copy number loss See cases [RCV000138434] Chr3:112465094..115774111 [GRCh38]
Chr3:112183941..115492958 [GRCh37]
Chr3:113666631..116975648 [NCBI36]
Chr3:3q13.2-13.31		 pathogenic
GRCh38/hg38 3q11.1-24(chr3:93800620-145695381)x3 copy number gain See cases [RCV000142340] Chr3:93800620..145695381 [GRCh38]
Chr3:93519464..145413168 [GRCh37]
Chr3:95002154..146895858 [NCBI36]
Chr3:3q11.1-24		 pathogenic
GRCh38/hg38 3q13.2-13.31(chr3:112425234-115795585)x1 copy number loss See cases [RCV000142219] Chr3:112425234..115795585 [GRCh38]
Chr3:112144081..115514432 [GRCh37]
Chr3:113626771..116997122 [NCBI36]
Chr3:3q13.2-13.31		 pathogenic
GRCh38/hg38 3q13.2-13.33(chr3:112520553-120031022)x1 copy number loss See cases [RCV000142725] Chr3:112520553..120031022 [GRCh38]
Chr3:112239400..119749869 [GRCh37]
Chr3:113722090..121232559 [NCBI36]
Chr3:3q13.2-13.33		 pathogenic
NM_017945.5(SLC35A5):c.353T>G (p.Leu118Arg) single nucleotide variant Monoclonal B-Cell Lymphocytosis [RCV000208563] Chr3:112570663 [GRCh38]
Chr3:112289510 [GRCh37]
Chr3:3q13.2		 uncertain significance
GRCh37/hg19 3q13.2-13.31(chr3:112144081-115514432)x1 copy number loss See cases [RCV000446223] Chr3:112144081..115514432 [GRCh37]
Chr3:3q13.2-13.31		 pathogenic
GRCh37/hg19 3q13.11-13.32(chr3:105094834-117441953)x1 copy number loss See cases [RCV000448410] Chr3:105094834..117441953 [GRCh37]
Chr3:3q13.11-13.32		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3q13.13-13.31(chr3:110645295-115103586)x1 copy number loss not provided [RCV000682294] Chr3:110645295..115103586 [GRCh37]
Chr3:3q13.13-13.31		 pathogenic
GRCh37/hg19 3q13.2-13.31(chr3:111894832-116930109)x1 copy number loss not provided [RCV000682296] Chr3:111894832..116930109 [GRCh37]
Chr3:3q13.2-13.31		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3q13.2(chr3:112211278-112308287)x3 copy number gain not provided [RCV000742694] Chr3:112211278..112308287 [GRCh37]
Chr3:3q13.2		 benign
GRCh37/hg19 3q13.2-13.31(chr3:112183943-115492949)x1 copy number loss not provided [RCV000856645] Chr3:112183943..115492949 [GRCh37]
Chr3:3q13.2-13.31		 pathogenic
GRCh37/hg19 3q13.2(chr3:111929014-112773945)x3 copy number gain not provided [RCV000847080] Chr3:111929014..112773945 [GRCh37]
Chr3:3q13.2		 uncertain significance
GRCh37/hg19 3q13.2(chr3:111929014-112773945)x3 copy number gain not provided [RCV000846844] Chr3:111929014..112773945 [GRCh37]
Chr3:3q13.2		 uncertain significance
GRCh37/hg19 3q13.2-13.31(chr3:112135341-115509260)x3 copy number gain not provided [RCV001259226] Chr3:112135341..115509260 [GRCh37]
Chr3:3q13.2-13.31		 pathogenic
GRCh37/hg19 3q13.2-13.31(chr3:112144081-115514432) copy number loss not specified [RCV002053367] Chr3:112144081..115514432 [GRCh37]
Chr3:3q13.2-13.31		 pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:20792 AgrOrtholog
COSMIC SLC35A5 COSMIC
Ensembl Genes ENSG00000138459 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000261034 ENTREZGENE
  ENSP00000261034.2 UniProtKB/TrEMBL
  ENSP00000417654 ENTREZGENE
  ENSP00000417654.1 UniProtKB/Swiss-Prot
  ENSP00000418265.1 UniProtKB/TrEMBL
  ENSP00000419958.1 UniProtKB/TrEMBL
  ENSP00000420398.1 UniProtKB/TrEMBL
Ensembl Transcript ENST00000261034 ENTREZGENE
  ENST00000261034.6 UniProtKB/TrEMBL
  ENST00000468642.5 UniProtKB/TrEMBL
  ENST00000484995.5 UniProtKB/TrEMBL
  ENST00000492406 ENTREZGENE
  ENST00000492406.6 UniProtKB/Swiss-Prot
  ENST00000494706.1 UniProtKB/TrEMBL
GTEx ENSG00000138459 GTEx
HGNC ID HGNC:20792 ENTREZGENE
Human Proteome Map SLC35A5 Human Proteome Map
InterPro Nuc_sug_transpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:55032 UniProtKB/Swiss-Prot
NCBI Gene 55032 ENTREZGENE
PANTHER PTHR10231 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Nuc_sug_transp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134947136 PharmGKB
PIRSF UDP-gal_transpt UniProtKB/Swiss-Prot
UniProt C9J7U8_HUMAN UniProtKB/TrEMBL
  C9JXZ8_HUMAN UniProtKB/TrEMBL
  F8WDF8_HUMAN UniProtKB/TrEMBL
  H7BXF8_HUMAN UniProtKB/TrEMBL
  L0R547_HUMAN UniProtKB/TrEMBL
  Q9BS91 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary D3DN66 UniProtKB/Swiss-Prot
  Q69YY6 UniProtKB/Swiss-Prot
  Q6ZMD6 UniProtKB/Swiss-Prot
  Q9NWM9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-08 SLC35A5  solute carrier family 35 member A5    solute carrier family 35, member A5  Symbol and/or name change 5135510 APPROVED