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Gene: S1PR2 (sphingosine-1-phosphate receptor 2) Homo sapiens
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Symbol: S1PR2
Name: sphingosine-1-phosphate receptor 2
Description: This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. [provided by RefSeq, Mar 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AGR16; CTD-2369P2.2; deafness, autosomal recessive 68; DFNB68; EDG-5; EDG5; endothelial differentiation G-protein coupled receptor 5; endothelial differentiation, sphingolipid G-protein-coupled receptor, 5; Gpcr13; H218; LPB2; S1P receptor 2; S1P receptor Edg-5; S1P receptor EDG5; S1P2; sphingosine 1-phosphate receptor 2; sphingosine 1-phosphate receptor Edg-5
Orthologs:
Mus musculus (house mouse) : S1pr2 (sphingosine-1-phosphate receptor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : S1pr2 (sphingosine-1-phosphate receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : S1pr2 (sphingosine-1-phosphate receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : S1PR2 (sphingosine-1-phosphate receptor 2)
Canis lupus familiaris (dog) : S1PR2 (sphingosine-1-phosphate receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : S1pr2 (sphingosine-1-phosphate receptor 2)
Sus scrofa (pig) : S1PR2 (sphingosine-1-phosphate receptor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,221,433 - 10,231,331 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371910,332,109 - 10,341,948 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,193,109 - 10,202,948 (-)NCBINCBI36hg18NCBI36
Build 341910,195,519 - 10,202,929NCBI
Celera1910,227,498 - 10,237,335 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef199,912,564 - 9,922,403 (-)NCBIHuRef
CHM1_11910,332,386 - 10,342,216 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on S1PR2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343937
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-17
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.