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Gene: S1PR2 (sphingosine-1-phosphate receptor 2) Homo sapiens
Symbol: S1PR2
Name: sphingosine-1-phosphate receptor 2
Description: This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. [provided by RefSeq, Mar 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AGR16; CTD-2369P2.2; deafness, autosomal recessive 68; DFNB68; EDG-5; EDG5; endothelial differentiation G-protein coupled receptor 5; endothelial differentiation, sphingolipid G-protein-coupled receptor, 5; Gpcr13; H218; LPB2; S1P receptor 2; S1P receptor Edg-5; S1P receptor EDG5; S1P2; sphingosine 1-phosphate receptor 2; sphingosine 1-phosphate receptor Edg-5
Mus musculus (house mouse) : S1pr2 (sphingosine-1-phosphate receptor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : S1pr2 (sphingosine-1-phosphate receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : S1pr2 (sphingosine-1-phosphate receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : S1PR2 (sphingosine-1-phosphate receptor 2)
Canis lupus familiaris (dog) : S1PR2 (sphingosine-1-phosphate receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : S1pr2 (sphingosine-1-phosphate receptor 2)
Sus scrofa (pig) : S1PR2 (sphingosine-1-phosphate receptor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381910,221,433 - 10,231,331 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371910,332,109 - 10,341,948 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,193,109 - 10,202,948 (-)NCBINCBI36hg18NCBI36
Build 341910,195,519 - 10,202,929NCBI
Celera1910,227,498 - 10,237,335 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef199,912,564 - 9,922,403 (-)NCBIHuRef
CHM1_11910,332,386 - 10,342,216 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on S1PR2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343937
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-17
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.