POPDC3 (popeye domain containing 3)

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Gene: POPDC3 (popeye domain containing 3) Homo sapiens

Analyze

Symbol:

POPDC3

Name:

popeye domain containing 3

RGD ID:

1343916

HGNC Page

HGNC

Description:

Predicted to have cAMP binding activity. Predicted to be involved in animal organ development; regulation of membrane potential; and striated muscle cell differentiation. Predicted to localize to sarcolemma. Implicated in autosomal recessive limb-girdle muscular dystrophy.

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

bA355M14.1; LGMDR26; MGC22671; POP3; popeye domain-containing protein 3; popeye protein 3; RP11-99L11.2

RGD Orthologs

Mouse

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Popdc3 (popeye domain containing 3)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Popdc3 (popeye domain containing 3)	HGNC	Ensembl, HomoloGene, NCBI, OMA, OrthoDB, Panther
Chinchilla lanigera (long-tailed chinchilla):	Popdc3 (popeye domain containing 3)	NCBI	Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):	POPDC3 (popeye domain containing 3)	NCBI	Ortholog
Canis lupus familiaris (dog):	POPDC3 (popeye domain containing 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Popdc3 (popeye domain containing 3)	NCBI	Ortholog
Sus scrofa (pig):	POPDC3 (popeye domain containing 3)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Chlorocebus sabaeus (African green monkey):	POPDC3 (popeye domain containing 3)	NCBI	Ortholog
Heterocephalus glaber (naked mole-rat):	Popdc3 (popeye domain containing 3)	NCBI	Ortholog
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Popdc3 (popeye domain containing 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Mus musculus (house mouse):	Popdc3 (popeye domain containing 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Danio rerio (zebrafish):	popdc3 (popeye domain containing 3)	Alliance	DIOPT (PhylomeDB\|Roundup\|TreeFam\|ZFIN)
Drosophila melanogaster (fruit fly):	bves	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup)

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	6	105,157,900 - 105,180,014 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	6	105,157,900 - 105,180,014 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	6	105,605,775 - 105,627,858 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	105,712,470 - 105,734,563 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	6	105,712,469 - 105,734,563	NCBI
Celera	6	106,227,913 - 106,249,989 (-)	NCBI
Cytogenetic Map	6	q21	NCBI
HuRef	6	103,048,673 - 103,070,745 (-)	NCBI		HuRef
CHM1_1	6	105,867,475 - 105,889,561 (-)	NCBI		CHM1_1

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 26 (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2-methylcholine (EXP)

aflatoxin B1 (EXP,ISO)

all-trans-retinoic acid (EXP)

arsane (EXP)

arsenic atom (EXP)

atrazine (EXP)

benzo[a]pyrene (EXP,ISO)

bisphenol A (EXP,ISO)

carbamazepine (EXP)

carbon nanotube (ISO)

carmustine (EXP)

choline (ISO)

cyclosporin A (EXP)

dorsomorphin (EXP)

doxorubicin (EXP)

entinostat (EXP)

folic acid (ISO)

gold atom (EXP)

gold(0) (EXP)

isoprenaline (ISO)

L-methionine (ISO)

lithium chloride (EXP)

mono(2-ethylhexyl) phthalate (ISO)

panobinostat (EXP)

PCB138 (ISO)

pirinixic acid (ISO)

SB 431542 (EXP)

sodium arsenate (EXP,ISO)

sodium arsenite (EXP)

sulforaphane (EXP)

sunitinib (EXP)

temozolomide (EXP)

tert-butyl hydroperoxide (EXP)

trichostatin A (EXP)

valproic acid (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

heart development (IBA)

regulation of membrane potential (IBA,ISS)

skeletal muscle tissue development (IBA)

striated muscle cell differentiation (IBA)

Cellular Component

integral component of membrane (NAS)

membrane (IEA)

sarcolemma (IBA)

Molecular Function

cAMP binding (IBA,ISS)

molecular_function (ND)

Phenotype Annotations Click to see Annotation Detail View

Human Phenotype

Autosomal recessive inheritance (IAGP)

Calf muscle hypertrophy (IAGP)

Difficulty running (IAGP)

Falls (IAGP)

Fatty replacement of skeletal muscle (IAGP)

Highly elevated creatine kinase (IAGP)

Increased variability in muscle fiber diameter (IAGP)

Muscle fiber necrosis (IAGP)

Proximal muscle weakness in lower limbs (IAGP)

References

References - curated


1.	Andree B, etal., Dev Biol 2000 Jul 15;223(2):371-82.
2.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8125298	PMID:12477932	PMID:14574404	PMID:15489334	PMID:17207965	PMID:18391951	PMID:19448622	PMID:19913121	PMID:20546612	PMID:20627872	PMID:20628086	PMID:21654844
PMID:21873635	PMID:22654436	PMID:28514442	PMID:28939104	PMID:31610034

Genomics

Comparative Map Data

POPDC3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	6	105,157,900 - 105,180,014 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	6	105,157,900 - 105,180,014 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	6	105,605,775 - 105,627,858 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	105,712,470 - 105,734,563 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	6	105,712,469 - 105,734,563	NCBI
Celera	6	106,227,913 - 106,249,989 (-)	NCBI
Cytogenetic Map	6	q21	NCBI
HuRef	6	103,048,673 - 103,070,745 (-)	NCBI		HuRef
CHM1_1	6	105,867,475 - 105,889,561 (-)	NCBI		CHM1_1

Popdc3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	45,165,401 - 45,194,546 (+)	NCBI	GRCm39		mm39
GRCm38	10	45,289,305 - 45,318,450 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	45,178,098 - 45,318,452 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	45,009,111 - 45,038,256 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	10	44,977,720 - 45,006,865 (+)	NCBI			mm8
Celera	10	46,163,076 - 46,192,460 (+)	NCBI		Celera
Cytogenetic Map	10	B2	NCBI
cM Map	10	23.35	NCBI

Popdc3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	20	50,394,617 - 50,422,551 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	50,394,650 - 50,422,560 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	52,006,146 - 52,033,991 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	20	51,221,107 - 51,249,040 (-)	NCBI		Celera
Cytogenetic Map	20	q13	NCBI

Popdc3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955411	30,564,194 - 30,571,767 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955411	30,566,988 - 30,573,158 (-)	NCBI	ChiLan1.0	ChiLan1.0

POPDC3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	6	106,846,321 - 106,864,675 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	106,846,329 - 106,850,599 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	6	102,972,263 - 102,993,986 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

POPDC3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	12	62,484,472 - 62,601,339 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	12	62,597,020 - 62,615,062 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Popdc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936564	1,840,270 - 1,860,894 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

POPDC3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	71,380,768 - 71,400,192 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	71,380,760 - 71,400,134 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	80,701,627 - 80,720,992 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

POPDC3
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	68,630,236 - 68,652,699 (+)	NCBI
ChlSab1.1 Ensembl	13	68,648,685 - 68,652,710 (+)	Ensembl

Popdc3
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624952	381,543 - 403,907 (-)	NCBI

Position Markers

WI-15170

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	105,605,856 - 105,605,960	UniSTS	GRCh37
Build 36	6	105,712,549 - 105,712,653	RGD	NCBI36
Celera	6	106,227,994 - 106,228,098	RGD
Cytogenetic Map	6	q21	UniSTS
HuRef	6	103,048,754 - 103,048,854	UniSTS
GeneMap99-GB4 RH Map	6	452.42	UniSTS
Whitehead-RH Map	6	679.0	UniSTS

RH93144

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	105,617,504 - 105,617,586	UniSTS	GRCh37
Build 36	6	105,724,197 - 105,724,279	RGD	NCBI36
Celera	6	106,239,646 - 106,239,728	RGD
Cytogenetic Map	6	q21	UniSTS
HuRef	6	103,060,400 - 103,060,482	UniSTS
GeneMap99-GB4 RH Map	6	456.24	UniSTS

AL008740

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	105,625,197 - 105,625,344	UniSTS	GRCh37
Build 36	6	105,731,890 - 105,732,037	RGD	NCBI36
Celera	6	106,247,338 - 106,247,485	RGD
Cytogenetic Map	6	q21	UniSTS
HuRef	6	103,068,094 - 103,068,241	UniSTS

RH46697

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	105,605,971 - 105,606,132	UniSTS	GRCh37
Build 36	6	105,712,664 - 105,712,825	RGD	NCBI36
Celera	6	106,228,109 - 106,228,270	RGD
Cytogenetic Map	6	q21	UniSTS
HuRef	6	103,048,865 - 103,049,026	UniSTS
GeneMap99-GB4 RH Map	6	457.16	UniSTS
NCBI RH Map	6	1378.2	UniSTS

POPDC3__5747

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	105,605,859 - 105,606,575	UniSTS	GRCh37
Build 36	6	105,712,552 - 105,713,268	RGD	NCBI36
Celera	6	106,227,997 - 106,228,713	RGD
HuRef	6	103,048,757 - 103,049,469	UniSTS

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	437
Count of miRNA genes:	291
Interacting mature miRNAs:	311
Transcripts:	ENST00000254765, ENST00000429112, ENST00000474760, ENST00000489134
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

visual system

adipose tissue

appendage

entire extraembryonic component

pharyngeal arch

High

Medium

631

150

1200

1127

960

262

164

1093

Low

1975

1457

495

119

342

1500

1017

2586

851

652

449

1015

Below cutoff

332

491

811

274

852

205

1571

184

189

317

759

744

651

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022361	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_024539	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_011536067	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017011194	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017011195	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF204171	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK225989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK314101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC022323	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BF244570	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CA433204	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471051	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENST00000254765 ⟹ ENSP00000254765

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	6	105,157,900 - 105,180,014 (-)	Ensembl

RefSeq Acc Id:

ENST00000429112 ⟹ ENSP00000414409

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	6	105,158,581 - 105,160,121 (-)	Ensembl

RefSeq Acc Id:

ENST00000474760

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	6	105,158,360 - 105,179,995 (-)	Ensembl

RefSeq Acc Id:

ENST00000489134

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	6	105,158,300 - 105,163,765 (-)	Ensembl

RefSeq Acc Id:

NM_022361 ⟹ NP_071756

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	6	105,157,900 - 105,180,014 (-)	NCBI
GRCh37	6	105,605,775 - 105,627,858 (-)	RGD
Build 36	6	105,712,470 - 105,734,563 (-)	NCBI Archive
Celera	6	106,227,913 - 106,249,989 (-)	RGD
HuRef	6	103,048,673 - 103,070,745 (-)	ENTREZGENE
CHM1_1	6	105,867,475 - 105,889,561 (-)	NCBI

Sequence:

show sequence

CACGCTGCGCCCGGCGCCGCAGGGTGGGCGGCGAGGCACTCACGAGGGGGACGCTGAGGGCTTC
CGCGCGGGCCACCCGGGTCAAGCGCGCTCCGCCGGGAAACTTCTGCGGGCGCCGGGCTGAAGCT
CCGGGCAGGGCTGGGAAGGAAAGGAAATACCAAAATATTTGCAGACTGGATCCAAATCAGGAGC
CCAGATGAACTTAAAGAAGCGAGCATGGGATTCTTAGTTTTTCAAGATCCGTACACACGAAGCC
TTTAATCAGCATCAACTCCAGTGTCCGTTTTCTCTGGTTTTGTGAAGACTGCACAAAACTCTCA
TGATGGAGAACCAAAGGACTTAGTTACCTGTTTCAGTGTCATCTAAAGTCAACTGAAAAGTGAA
GCAGGCAGTAATACAGCCATGGAAAGAAATTCAAGTTTATGGAAGAACCTAATAGATGAACACC
CAGTCTGCACAACCTGGAAGCAAGAGGCCGAAGGAGCCATTTATCATCTTGCCAGTATTTTATT
TGTAGTAGGTTTCATGGGTGGCAGTGGATTCTTCGGGCTCCTTTATGTCTTCAGTTTGCTGGGG
TTGGGTTTTCTCTGTTCTGCTGTCTGGGCTTGGGTAGATGTCTGTGCAGCTGACATATTTTCCT
GGAATTTTGTACTGTTTGTCATCTGCTTCATGCAATTTGTTCATATTGCATATCAAGTTCGCAG
CATAACCTTTGCCCGAGAATTCCAAGTGTTGTACAGCTCCCTTTTCCAGCCCCTGGGGATCTCT
TTGCCTGTCTTCAGAACGATTGCTTTGAGCTCTGAAGTGGTTACTTTGGAAAAGGAACACTGTT
ATGCCATGCAGGGGAAAACTTCCATTGATAAACTCTCCTTGCTTGTTTCAGGAAGGATCAGAGT
GACAGTTGATGGCGAATTTCTGCATTACATTTTCCCCCTTCAGTTCCTGGATTCTCCTGAGTGG
GATTCACTGAGACCCACAGAGGAAGGCATTTTTCAGGTAACCCTCACTGCAGAAACTGATTGTC
GATATGTGTCTTGGAGGAGAAAGAAATTATATCTGCTCTTTGCTCAGCATCGCTACATCTCCCG
CCTTTTTTCAGTGCTAATTGGCAGTGACATTGCAGATAAACTCTATGCCTTGAATGACAGGGTA
TATATAGGAAAAAGATATCACTATGATATTCGGCTACCCAACTTCTATCAAATGTCAACTCCAG
AAATACGCAGATCACCCCTGACACAACATTTTCAGAATTCCAGACGATACTGTGATAAATGACA
TCAAAGTCTGAAATTTATAAGTATAAAAAAAGACTCTCTCTTCATCATTCCCCAGTGAAATAGC
AAAATACAAAAAAAGAGCTCCCTAATGTTTTTATAAATCAAATTCAGAAGCGAGATGCCATTGC
CAACTGTTTTATTCCTTTCAACAACTGCATTGTGAATAAACTTTACAAATTTTTCTTGTATTTC
TCATTGTTATAATTGGGGAGGGGGTGGATAACTATGGGCAGTTTGCCCTTTTCTGCATCAAAAC
TGGGAGAATGAAATTCCACTTTCTCAATTCTTTTCTCACATTTACTCAAATGCATTGTCTTGCC
CTATAGACTCAGGAGTTGCTTCTCAAGAAAGAGCCAGCAAGTATTCTCAGCCTGAGGGTGGGTT
GCTACTGTCCACATAGGCATTTCCGGAATTCACTTTTTTGCTACAACCTCCAGTGAAAGCAATT
ATTTATTTTAAATGTGCAGTTACTTGATGCGACTAAAAAGTAGAATAAATGCAAGAGATAATAA
TATGTGAATCTTGAAGCCTATTTTATTGCTACAAATAAAATAACATTTAAAAAGAA

hide sequence

RefSeq Acc Id:

NR_024539

RefSeq Status:

REVIEWED

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	6	105,157,900 - 105,176,255 (-)	NCBI
GRCh37	6	105,605,775 - 105,627,858 (-)	RGD
Celera	6	106,227,913 - 106,249,989 (-)	RGD
HuRef	6	103,048,673 - 103,070,745 (-)	ENTREZGENE
CHM1_1	6	105,867,475 - 105,885,836 (-)	NCBI

Sequence:

show sequence

AGAGCTCTGTGAACCTCTTCTGGTTGTGAGTGCTGCCTGATTCGTGAGTTGTTTGTTGCTCAGG
AAATACCAAAATATTTGCAGACTGGATCCAAATCAGGAGCCCAGATGAACTTAAAGAAGCGAGC
ATGGGATTCTTAGTTTTTCAAGATCCGTACACACGAAGCCTTTAATCAGCATCAACTCCAGTGT
CCGTTTTCTCTGGTTTTGTGAAGACTGCACAAAACTCTCATGATGGAGAACCAAAGGACTTAGT
TACCTGTTTCAGTGTCATCTAAAGTCAACTGAAAAGTGAAGCAGGCAGTAATACAGCCATGGAA
AGAAATTCAAGTTTATGGAAGAACCTAATAGATGAACACCCAGTCTGCACAACCTGGAAGCAAG
AGGCCGAAGGAGCCATTTATCATCTTGCCAGTATTTTATTTGTAGATCAGAGTGACAGTTGATG
GCGAATTTCTGCATTACATTTTCCCCCTTCAGTTCCTGGATTCTCCTGAGTGGGATTCACTGAG
ACCCACAGAGGAAGGCATTTTTCAGGTAACCCTCACTGCAGAAACTGATTGTCGATATGTGTCT
TGGAGGAGAAAGAAATTATATCTGCTCTTTGCTCAGCATCGCTACATCTCCCGCCTTTTTTCAG
TGCTAATTGGCAGTGACATTGCAGATAAACTCTATGCCTTGAATGACAGGGTATATATAGGAAA
AAGATATCACTATGATATTCGGCTACCCAACTTCTATCAAATGTCAACTCCAGAAATACGCAGA
TCACCCCTGACACAACATTTTCAGAATTCCAGACGATACTGTGATAAATGACATCAAAGTCTGA
AATTTATAAGTATAAAAAAAGACTCTCTCTTCATCATTCCCCAGTGAAATAGCAAAATACAAAA
AAAGAGCTCCCTAATGTTTTTATAAATCAAATTCAGAAGCGAGATGCCATTGCCAACTGTTTTA
TTCCTTTCAACAACTGCATTGTGAATAAACTTTACAAATTTTTCTTGTATTTCTCATTGTTATA
ATTGGGGAGGGGGTGGATAACTATGGGCAGTTTGCCCTTTTCTGCATCAAAACTGGGAGAATGA
AATTCCACTTTCTCAATTCTTTTCTCACATTTACTCAAATGCATTGTCTTGCCCTATAGACTCA
GGAGTTGCTTCTCAAGAAAGAGCCAGCAAGTATTCTCAGCCTGAGGGTGGGTTGCTACTGTCCA
CATAGGCATTTCCGGAATTCACTTTTTTGCTACAACCTCCAGTGAAAGCAATTATTTATTTTAA
ATGTGCAGTTACTTGATGCGACTAAAAAGTAGAATAAATGCAAGAGATAATAATATGTGAATCT
TGAAGCCTATTTTATTGCTACAAATAAAATAACATTTAAAAAGAA

hide sequence

RefSeq Acc Id:

XM_011536067 ⟹ XP_011534369

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	6	105,158,280 - 105,176,504 (-)	NCBI

Sequence:

show sequence

GGAGGCCATTAGCCTGAGTCTTTCTCCCTACTTTGAGTCCCTGTGTGAAAAACTAACTTTGTAC
ATAAACGAACAGAAAACTAACTCAACAGTGTATTTTTTGTAATAGCCAGGTTTCAGCCAATCAC
AGGCGGCCAGCTCATCACATTATGCCCAAATAAAGCAGATGCAGAGCTGTAGCCAATCGAGTGA
TTTTGGTTTTTTACTTCTGTCATCAGTGTATAAAAACTGCAGCTCATGCTGCTGGATAGAGCTC
TGTGAACCTCTTCTGGTTGTGAGTGCTGCCTGATTCGTGAGTTGTTTGTTGCTCAGGAAATACC
AAAATATTTGCAGACTGGATCCAAATCAGGAGCCCAGATGAACTTAAAGAAGCGAGCATGGGAT
TCTTAGTTTTTCAAGATCCGTACACACGAAGCCTTTAATCAGCATCAACTCCAGTGTCCGTTTT
CTCTGGTTTTGTGAAGACTGCACAAAACTCTCATGATGGAGAACCAAAGGACTTAGTTACCTGT
TTCAGTGTCATCTAAAGTCAACTGAAAAGTGAAGCAGGCAGTAATACAGCCATGGAAAGAAATT
CAAGTTTATGGAAGAACCTAATAGATGAACACCCAGTCTGCACAACCTGGAAGCAAGAGGCCGA
AGGAGCCATTTATCATCTTGCCAGTATTTTATTTGTAGTAGGTTTCATGGGTGGCAGTGGATTC
TTCGGGCTCCTTTATGTCTTCAGTTTGCTGGGGTTGGGTTTTCTCTGTTCTGCTGTCTGGGCTT
GGGTAGATGTCTGTGCAGCTGACATATTTTCCTGGAATTTTGTACTGTTTGTCATCTGCTTCAT
GCAATTTGTTCATATTGCATATCAAGTTCGCAGCATAACCTTTGCCCGAGAATTCCAAGTGTTG
TACAGCTCCCTTTTCCAGCCCCTGGGGATCTCTTTGCCTGTCTTCAGAACGATTGCTTTGAGCT
CTGAAGTGGTTACTTTGGAAAAGGAACACTGTTATGCCATGCAGGGGAAAACTTCCATTGATAA
ACTCTCCTTGCTTGTTTCAGGAAGGATCAGAGTGACAGTTGATGGCGAATTTCTGCATTACATT
TTCCCCCTTCAGTTCCTGGATTCTCCTGAGTGGGATTCACTGAGACCCACAGAGGAAGGCATTT
TTCAGGTAACCCTCACTGCAGAAACTGATTGTCGATATGTGTCTTGGAGGAGAAAGAAATTATA
TCTGCTCTTTGCTCAGCATCGCTACATCTCCCGCCTTTTTTCAGTGCTAATTGGCAGTGACATT
GCAGATAAACTCTATGCCTTGAATGACAGGGTATATATAGGAAAAAGATATCACTATGATATTC
GGCTACCCAACTTCTATCAAATGTCAACTCCAGAAATACGCAGATCACCCCTGACACAACATTT
TCAGAATTCCAGACGATACTGTGATAAATGACATCAAAGTCTGAAATTTATAAGTATAAAAAAA
GACTCTCTCTTCATCATTCCCCAGTGAAATAGCAAAATACAAAAAAAGAGCTCCCTAATGTTTT
TATAAATCAAATTCAGAAGCGAGATGCCATTGCCAACTGTTTTATTCCTTTCAACAACTGCATT
GTGAATAAACTTTACAAATTTTTCTTGTA

hide sequence

RefSeq Acc Id:

XM_017011194 ⟹ XP_016866683

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	6	105,158,280 - 105,165,256 (-)	NCBI

Sequence:

show sequence

TTATTTTCTTGGCAAAGCAGCCCTGGAAGAATATCCCACTTGGGTTCCCCAAAACATTAATATT
TGATTCACAGTCTTGAGAGCTGGCACTGAATGTTGGAGAGGGTCTAAAGAGGGGCGGACGGGAA
TTGGAGCTCCATGCCACCACCTGTTTTACCTGAAGCCAGAGACTCAACCAATCTGTGCCCTTCT
TTTCTCATTTGTAAGCTGGACATGATGATTTAGATTCTGCCTCCCTCGTGGCAATGAGATAATA
AATGCAGAAGTTCTGTTGCAATAAATGCAGTTTCTAGCTAATTTGCCAGCAGGTTTACTTTGCA
TTTCATTGAGCATCCTTGTATCTTCATTTACATTTCCTATTCCTTTATAACTCGTAATCTTAAC
AATTTAAAGAGAAAAAAACCCAGATGAGCTTGGAACAACTGTGTTTATTTGCACTTAAGTTTGT
CTTCATCATTTGTAGCTCAGTGTGCTAACTTACTTTGCAGTGAAGATCAACTCTAGTGCTTAGG
AAAGAAATCCATTGTGCCACTTTGGCATGTCAGCATTTATTTACGCAAAACATGACCTCAGGCT
TACAGGCCTTTAAGGCAGACAGCTGGTTGATGAATCATGTTGGACATTCATATAGTGCTGCTGG
CACATGTCAGAAGGACACTCCTGCTCATCACCTGCCCCTGTCAGTTCTTCCACTTCTAATAAAG
CATATCTGTTTTGGTGACCAAATAAAAACACAAGTGAAGAAGGGCTGGGTGTGGAGTAATTTAA
TCAGGGCAAGTCAGCACGCTGCATTGAGCAGTACAGTATCAAGGATAAAAAGATGGTTTGGTAA
CAGCTGAATGAAACGAAGTAGATTAGTAAAGATGGAAGCACAGTTCCCCTTATAATCATAATGG
GTCATGACCCTGGAATGCAGAAGCCCCAATATATCCTACAAATCAAGATTTTTAAGGAGACAGG
ATTCCCAGAAGTTCCCTTCTGAATTGCCACGAACGTTTTACATGGCCTTTCTCTATTAGCATCA
TTTTAACATTTCGCTGAGGATTATAAATTTTTAAGGAAGTTCAAACCAAAGTTCAGAGCTCCAC
TAGCAAATCTTTTTAAACTGGCTTTCGTGGGTGTGTTTGGTATCCTGAAGAATTGATTGATTTA
AAATACCCTAGTTTTGAAACAGCAGGGAGACTGACATTTGCAGCCTGGTATTTTGCAGTTCTCA
CTACTCATTGTATTTGAACAATAATTTTTCTTTGTTGTAATACCCAGTAGAATAAAATTTTGTG
CTTTGTTTAAAAGAGGAGAAATTGAACATGTTCAGGATGCTGGCCTGTCTTCAATTTCATCACC
ATCATCTCGTAGATTGATTGATGGGGAGAATAATTAGGGATATGCAGCATGTTTGAAATGTATT
TGAAAACAAGCAAAAACAACAATATGACTATAAGTTGTAAGTCTAAGCTTTTTTTTTCTTTTTT
TTTAAATGATTCACCTGGCAGTGTTCTTGAAGTCATTACTTACTGAGAAAAGAATCACTATCCA
AGATGAAAAATCAGGAACTTCAACAACAGCTCCTTTATTTCCATTTCTACTTCTGTTGGAAATA
CCAAAATATTTGCAGACTGGATCCAAATCAGGAGCCCAGATGAACTTAAAGAAGCGAGCATGGG
ATTCTTAGTTTTTCAAGATCCGTACACACGAAGCCTTTAATCAGCATCAACTCCAGTGTCCGTT
TTCTCTGGTTTTGTGAAGACTGCACAAAACTCTCATGATGGAGAACCAAAGGACTTAGTTACCT
GTTTCAGTGTCATCTAAAGTCAACTGAAAAGTGAAGCAGGCAGTAATACAGCCATGGAAAGAAA
TTCAAGTTTATGGAAGAACCTAATAGATGAACACCCAGTCTGCACAACCTGGAAGCAAGAGGCC
GAAGGAGCCATTTATCATCTTGCCAGTATTTTATTTGTAGTAGGTTTCATGGGTGGCAGTGGAT
TCTTCGGGCTCCTTTATGTCTTCAGTTTGCTGGGGTTGGGTTTTCTCTGTTCTGCTGTCTGGGC
TTGGGTAGATGTCTGTGCAGCTGACATATTTTCCTGGAATTTTGTACTGTTTGTCATCTGCTTC
ATGCAATTTGTTCATATTGCATATCAAGTTCGCAGCATAACCTTTGCCCGAGAATTCCAAGTGT
TGTACAGCTCCCTTTTCCAGCCCCTGGGGATCTCTTTGCCTGTCTTCAGAACGATTGCTTTGAG
CTCTGAAGTGGTTACTTTGGAAAAGGAACACTGTTATGCCATGCAGGGGAAAACTTCCATTGAT
AAACTCTCCTTGCTTGTTTCAGGAAGGATCAGAGTGACAGTTGATGGCGAATTTCTGCATTACA
TTTTCCCCCTTCAGTTCCTGGATTCTCCTGAGTGGGATTCACTGAGACCCACAGAGGAAGGCAT
TTTTCAGGTAACCCTCACTGCAGAAACTGATTGTCGATATGTGTCTTGGAGGAGAAAGAAATTA
TATCTGCTCTTTGCTCAGCATCGCTACATCTCCCGCCTTTTTTCAGTGCTAATTGGCAGTGACA
TTGCAGATAAACTCTATGCCTTGAATGACAGGGTATATATAGGAAAAAGATATCACTATGATAT
TCGGCTACCCAACTTCTATCAAATGTCAACTCCAGAAATACGCAGATCACCCCTGACACAACAT
TTTCAGAATTCCAGACGATACTGTGATAAATGACATCAAAGTCTGAAATTTATAAGTATAAAAA
AAGACTCTCTCTTCATCATTCCCCAGTGAAATAGCAAAATACAAAAAAAGAGCTCCCTAATGTT
TTTATAAATCAAATTCAGAAGCGAGATGCCATTGCCAACTGTTTTATTCCTTTCAACAACTGCA
TTGTGAATAAACTTTACAAATTTTTCTTGTA

hide sequence

RefSeq Acc Id:

XM_017011195 ⟹ XP_016866684

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	6	105,158,280 - 105,163,640 (-)	NCBI

Sequence:

show sequence

TACTCCAGCTAAGTCATTTTCACCTCTGTATTTTTTCTCCTATGGGGCAAGATCTGTGATATCT
GATAGTTTATTAACAGGTGTGCTGGAAATAATCTATTTCAAAAATAAAACACTAAATATAGCAC
ACAAGTTCAAGGCTTTTGAATGTTACCATGGTTTTAAAAAATCAATGTCATGAATGCTTTACAC
TGAAATCATTTATTGTTAGGAAACTGGGTGGCAAATGATACATATATCCTGTAGCTCTGTCATC
ATGGCTAATGCTCTCCTGACTCAGATTACATATTAGCATTTCCACCATATGGCTGAAAGGGTAG
AGAATGTATGTGCAGAGGAACAGAGTTGGTAATATTTTTGACCATCTGATAAATAAATATGTAA
GTAACAGGAATATTAATATTTATTTCATCATATGATGCAAGCTTTAACCTGAAATAACCACTAA
TACAACAAAGTAGTACATTTGTTTCTCAAATAATTTCAATCTAATTTATTAAATATTTCCATAG
TCAATTAATGCTCTTAGAATGTGACTTCTAATTATGTTTCTTATGTTTATTGATATAGTAGGGT
TCCTTATCATGCCAAATTTAAAAATCTTTCCTGAGAGGCCACACGATTGGACCCAGCATATGGG
CATGAGCGCCAAAGTTCTGCTCTGCCAGTGACCACTGTGTGGCCTGGGATAAATTACCTGACCT
CTCTAAGCCTCAAATTAATGTGTAAAGAGTGAATAATCTATTATCAGACAGTATCCCTCAAAGG
GTGGGCCATGGAGGACCATGGATTAACACATCAGAATCACATGGGGAGCTTAAAATACAAACAT
CTGGGCCCCACCCGCAATGATTCTGGTTCATGTATCTGGAAGCAGTCCATGAATCTGCAAATAT
ATATATGTATTAATACAGAGTCTTACTCTTTTCGCCTAGGCTGAAGTGCAGTGGTAAGATGATC
TCGGCTCACTGAAGCCTGTCTCCCAAGTTCAAGTGATTCTTGTGCCTCAGCATCCTGAGTAGCT
GGGATCCCAGGCGCACGCCACCACGCCTGGGAAATACCAAAATATTTGCAGACTGGATCCAAAT
CAGGAGCCCAGATGAACTTAAAGAAGCGAGCATGGGATTCTTAGTTTTTCAAGATCCGTACACA
CGAAGCCTTTAATCAGCATCAACTCCAGTGTCCGTTTTCTCTGGTTTTGTGAAGACTGCACAAA
ACTCTCATGATGGAGAACCAAAGGACTTAGTTACCTGTTTCAGTGTCATCTAAAGTCAACTGAA
AAGTGAAGCAGGCAGTAATACAGCCATGGAAAGAAATTCAAGTTTATGGAAGAACCTAATAGAT
GAACACCCAGTCTGCACAACCTGGAAGCAAGAGGCCGAAGGAGCCATTTATCATCTTGCCAGTA
TTTTATTTGTAGTAGGTTTCATGGGTGGCAGTGGATTCTTCGGGCTCCTTTATGTCTTCAGTTT
GCTGGGGTTGGGTTTTCTCTGTTCTGCTGTCTGGGCTTGGGTAGATGTCTGTGCAGCTGACATA
TTTTCCTGGAATTTTGTACTGTTTGTCATCTGCTTCATGCAATTTGTTCATATTGCATATCAAG
TTCGCAGCATAACCTTTGCCCGAGAATTCCAAGTGTTGTACAGCTCCCTTTTCCAGCCCCTGGG
GATCTCTTTGCCTGTCTTCAGAACGATTGCTTTGAGCTCTGAAGTGGTTACTTTGGAAAAGGAA
CACTGTTATGCCATGCAGGGGAAAACTTCCATTGATAAACTCTCCTTGCTTGTTTCAGGAAGGA
TCAGAGTGACAGTTGATGGCGAATTTCTGCATTACATTTTCCCCCTTCAGTTCCTGGATTCTCC
TGAGTGGGATTCACTGAGACCCACAGAGGAAGGCATTTTTCAGGTAACCCTCACTGCAGAAACT
GATTGTCGATATGTGTCTTGGAGGAGAAAGAAATTATATCTGCTCTTTGCTCAGCATCGCTACA
TCTCCCGCCTTTTTTCAGTGCTAATTGGCAGTGACATTGCAGATAAACTCTATGCCTTGAATGA
CAGGGTATATATAGGAAAAAGATATCACTATGATATTCGGCTACCCAACTTCTATCAAATGTCA
ACTCCAGAAATACGCAGATCACCCCTGACACAACATTTTCAGAATTCCAGACGATACTGTGATA
AATGACATCAAAGTCTGAAATTTATAAGTATAAAAAAAGACTCTCTCTTCATCATTCCCCAGTG
AAATAGCAAAATACAAAAAAAGAGCTCCCTAATGTTTTTATAAATCAAATTCAGAAGCGAGATG
CCATTGCCAACTGTTTTATTCCTTTCAACAACTGCATTGTGAATAAACTTTACAAATTTTTCTT
GTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_071756	(Get FASTA)	NCBI Sequence Viewer
	XP_011534369	(Get FASTA)	NCBI Sequence Viewer
	XP_016866683	(Get FASTA)	NCBI Sequence Viewer
	XP_016866684	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAG23404	(Get FASTA)	NCBI Sequence Viewer
	AAH22323	(Get FASTA)	NCBI Sequence Viewer
	BAG36795	(Get FASTA)	NCBI Sequence Viewer
	EAW48427	(Get FASTA)	NCBI Sequence Viewer
	EAW48428	(Get FASTA)	NCBI Sequence Viewer
	Q9HBV1	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_071756 ⟸ NM_022361

- UniProtKB:

Q9HBV1 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MERNSSLWKNLIDEHPVCTTWKQEAEGAIYHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLCS
AVWAWVDVCAADIFSWNFVLFVICFMQFVHIAYQVRSITFAREFQVLYSSLFQPLGISLPVFRT
IALSSEVVTLEKEHCYAMQGKTSIDKLSLLVSGRIRVTVDGEFLHYIFPLQFLDSPEWDSLRPT
EEGIFQVTLTAETDCRYVSWRRKKLYLLFAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKRY
HYDIRLPNFYQMSTPEIRRSPLTQHFQNSRRYCDK

hide sequence

RefSeq Acc Id:	XP_011534369 ⟸ XM_011536067
- Peptide Label:	isoform X1
- UniProtKB:	Q9HBV1 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MERNSSLWKNLIDEHPVCTTWKQEAEGAIYHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLCS AVWAWVDVCAADIFSWNFVLFVICFMQFVHIAYQVRSITFAREFQVLYSSLFQPLGISLPVFRT IALSSEVVTLEKEHCYAMQGKTSIDKLSLLVSGRIRVTVDGEFLHYIFPLQFLDSPEWDSLRPT EEGIFQVTLTAETDCRYVSWRRKKLYLLFAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKRY HYDIRLPNFYQMSTPEIRRSPLTQHFQNSRRYCDK hide sequence

RefSeq Acc Id:	XP_016866683 ⟸ XM_017011194
- Peptide Label:	isoform X1
- UniProtKB:	Q9HBV1 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MERNSSLWKNLIDEHPVCTTWKQEAEGAIYHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLCS AVWAWVDVCAADIFSWNFVLFVICFMQFVHIAYQVRSITFAREFQVLYSSLFQPLGISLPVFRT IALSSEVVTLEKEHCYAMQGKTSIDKLSLLVSGRIRVTVDGEFLHYIFPLQFLDSPEWDSLRPT EEGIFQVTLTAETDCRYVSWRRKKLYLLFAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKRY HYDIRLPNFYQMSTPEIRRSPLTQHFQNSRRYCDK hide sequence

RefSeq Acc Id:	XP_016866684 ⟸ XM_017011195
- Peptide Label:	isoform X1
- UniProtKB:	Q9HBV1 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MERNSSLWKNLIDEHPVCTTWKQEAEGAIYHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLCS AVWAWVDVCAADIFSWNFVLFVICFMQFVHIAYQVRSITFAREFQVLYSSLFQPLGISLPVFRT IALSSEVVTLEKEHCYAMQGKTSIDKLSLLVSGRIRVTVDGEFLHYIFPLQFLDSPEWDSLRPT EEGIFQVTLTAETDCRYVSWRRKKLYLLFAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKRY HYDIRLPNFYQMSTPEIRRSPLTQHFQNSRRYCDK hide sequence

RefSeq Acc Id:

ENSP00000254765 ⟸ ENST00000254765

RefSeq Acc Id:

ENSP00000414409 ⟸ ENST00000429112

Promoters

RGD ID:

7208785

Promoter ID:

EPDNEW_H10138

Type:

initiation region

Name:

POPDC3_2

Description:

popeye domain containing 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H10139

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	6	105,176,255 - 105,176,315	EPDNEW

RGD ID:

7208787

Promoter ID:

EPDNEW_H10139

Type:

initiation region

Name:

POPDC3_1

Description:

popeye domain containing 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H10138

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	6	105,179,900 - 105,179,960	EPDNEW

RGD ID:

6804566

Promoter ID:

HG_KWN:54480

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

K562

Transcripts:

UC003PRA.1

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	6	105,730,456 - 105,730,956 (-)	MPROMDB

RGD ID:

6804546

Promoter ID:

HG_KWN:54481

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

HeLa_S3, NB4

Transcripts:

OTTHUMT00000041652, UC003PRB.1

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	6	105,734,201 - 105,734,701 (-)	MPROMDB

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
NM_022361.4(POPDC3):c.360G>A (p.Gly120=)	single nucleotide variant	Malignant melanoma [RCV000067057]	Chr6:105161550 [GRCh38] Chr6:105609425 [GRCh37] Chr6:105716118 [NCBI36] Chr6:6q21	not provided
NM_022361.4(POPDC3):c.384G>A (p.Thr128=)	single nucleotide variant	Malignant melanoma [RCV000061287]	Chr6:105161526 [GRCh38] Chr6:105609401 [GRCh37] Chr6:105716094 [NCBI36] Chr6:6q21	not provided
NM_022361.4(POPDC3):c.80G>A (p.Gly27Glu)	single nucleotide variant	Malignant melanoma [RCV000061288]	Chr6:105161830 [GRCh38] Chr6:105609705 [GRCh37] Chr6:105716398 [NCBI36] Chr6:6q21	not provided
GRCh38/hg38 6q16.3-21(chr6:102356502-111049879)x1	copy number loss	See cases [RCV000134806]	Chr6:102356502..111049879 [GRCh38] Chr6:102804377..111371082 [GRCh37] Chr6:102911070..111477775 [NCBI36] Chr6:6q16.3-21	pathogenic
GRCh38/hg38 6q13-24.1(chr6:74382807-142040500)x3	copy number gain	See cases [RCV000139729]	Chr6:74382807..142040500 [GRCh38] Chr6:75092523..142361637 [GRCh37] Chr6:75149243..142403330 [NCBI36] Chr6:6q13-24.1	pathogenic
GRCh38/hg38 6q16.1-22.31(chr6:96609994-122161548)x1	copy number loss	See cases [RCV000139465]	Chr6:96609994..122161548 [GRCh38] Chr6:97057870..122482694 [GRCh37] Chr6:97164591..122524393 [NCBI36] Chr6:6q16.1-22.31	pathogenic
GRCh38/hg38 6q16.3-21(chr6:103279465-113934239)x1	copy number loss	See cases [RCV000142287]	Chr6:103279465..113934239 [GRCh38] Chr6:103727340..114255403 [GRCh37] Chr6:103834033..114362096 [NCBI36] Chr6:6q16.3-21	pathogenic
GRCh38/hg38 6q16.3-22.31(chr6:100054889-120488154)x1	copy number loss	See cases [RCV000143227]	Chr6:100054889..120488154 [GRCh38] Chr6:100502765..120809300 [GRCh37] Chr6:100609486..120850999 [NCBI36] Chr6:6q16.3-22.31	pathogenic
GRCh37/hg19 6q14.3-22.31(chr6:85988428-120548687)x1	copy number loss	See cases [RCV000445666]	Chr6:85988428..120548687 [GRCh37] Chr6:6q14.3-22.31	pathogenic
GRCh37/hg19 6q21(chr6:105550491-107378236)x1	copy number loss	See cases [RCV000448307]	Chr6:105550491..107378236 [GRCh37] Chr6:6q21	uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3	copy number gain	See cases [RCV000512067]	Chr6:156975..170919482 [GRCh37] Chr6:6p25.3-q27	pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)	copy number gain	See cases [RCV000510595]	Chr6:156975..170919482 [GRCh37] Chr6:6p25.3-q27	pathogenic
GRCh37/hg19 6q16.1-21(chr6:97384446-110247755)x1	copy number loss	See cases [RCV000510703]	Chr6:97384446..110247755 [GRCh37] Chr6:6q16.1-21	pathogenic
GRCh37/hg19 6q16.1-21(chr6:94202605-109878834)x1	copy number loss	See cases [RCV000512470]	Chr6:94202605..109878834 [GRCh37] Chr6:6q16.1-21	pathogenic
GRCh37/hg19 6q16.1-22.1(chr6:95549951-116684929)x1	copy number loss	not provided [RCV000682693]	Chr6:95549951..116684929 [GRCh37] Chr6:6q16.1-22.1	pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3	copy number gain	not provided [RCV000745400]	Chr6:60107..171054786 [GRCh37] Chr6:6p25.3-q27	pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3	copy number gain	not provided [RCV000745404]	Chr6:165632..170919470 [GRCh37] Chr6:6p25.3-q27	pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3	copy number gain	not provided [RCV000745403]	Chr6:108666..170980171 [GRCh37] Chr6:6p25.3-q27	pathogenic
NM_022361.5(POPDC3):c.12T>C (p.Asn4=)	single nucleotide variant	not provided [RCV000958863]	Chr6:105161898 [GRCh38] Chr6:105609773 [GRCh37] Chr6:6q21	benign
NM_022361.5(POPDC3):c.516G>A (p.Leu172=)	single nucleotide variant	not provided [RCV000958862]	Chr6:105159789 [GRCh38] Chr6:105607664 [GRCh37] Chr6:6q21	benign
GRCh37/hg19 6q21(chr6:105538029-105659133)x1	copy number loss	not provided [RCV000848904]	Chr6:105538029..105659133 [GRCh37] Chr6:6q21	uncertain significance
NM_022361.5(POPDC3):c.395G>A (p.Ser132Asn)	single nucleotide variant	not provided [RCV000889608]	Chr6:105161515 [GRCh38] Chr6:105609390 [GRCh37] Chr6:6q21	benign
GRCh37/hg19 6q21(chr6:105585683-106158458)x3	copy number gain	not provided [RCV001007553]	Chr6:105585683..106158458 [GRCh37] Chr6:6q21	likely benign
NM_022361.5(POPDC3):c.651A>T (p.Leu217Phe)	single nucleotide variant	MUSCULAR DYSTROPHY, LIMB-GIRDLE, AUTOSOMAL RECESSIVE 26 [RCV001078199]	Chr6:105158695 [GRCh38] Chr6:105606570 [GRCh37] Chr6:6q21	pathogenic
NM_022361.5(POPDC3):c.782G>A (p.Arg261Gln)	single nucleotide variant	MUSCULAR DYSTROPHY, LIMB-GIRDLE, AUTOSOMAL RECESSIVE 26 [RCV001078197]	Chr6:105158564 [GRCh38] Chr6:105606439 [GRCh37] Chr6:6q21	pathogenic
NM_022361.5(POPDC3):c.464T>A (p.Leu155His)	single nucleotide variant	MUSCULAR DYSTROPHY, LIMB-GIRDLE, AUTOSOMAL RECESSIVE 26 [RCV001078198]	Chr6:105161446 [GRCh38] Chr6:105609321 [GRCh37] Chr6:6q21	pathogenic
GRCh37/hg19 6q16.3-22.1(chr6:101296547-117004249)x3	copy number gain	Microcephaly [RCV001251053]	Chr6:101296547..117004249 [GRCh37] Chr6:6q16.3-22.1	pathogenic
GRCh37/hg19 6q16.1-21(chr6:98949950-114533905)x1	copy number loss	Deletion 6q16 q21 [RCV001263224]	Chr6:98949950..114533905 [GRCh37] Chr6:6q16.1-21	pathogenic

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:17649	AgrOrtholog
COSMIC	POPDC3	COSMIC
Ensembl Genes	ENSG00000132429	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSP00000254765	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSP00000414409	UniProtKB/TrEMBL
Ensembl Transcript	ENST00000254765	ENTREZGENE, UniProtKB/Swiss-Prot
	ENST00000429112	UniProtKB/TrEMBL
GTEx	ENSG00000132429	GTEx
HGNC ID	HGNC:17649	ENTREZGENE
Human Proteome Map	POPDC3	Human Proteome Map
InterPro	cNMP-bd-like	UniProtKB/Swiss-Prot
	Popeye_prot	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	hsa:64208	UniProtKB/Swiss-Prot
NCBI Gene	64208	ENTREZGENE
OMIM	605824	OMIM
	618848	OMIM
PANTHER	PTHR12101	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Popeye	UniProtKB/Swiss-Prot
PharmGKB	PA134935151	PharmGKB
Superfamily-SCOP	SSF51206	UniProtKB/Swiss-Prot
UniGene	Hs.458336	ENTREZGENE
UniProt	POPD3_HUMAN	UniProtKB/Swiss-Prot
	Q5T554_HUMAN	UniProtKB/TrEMBL
	Q9HBV1	ENTREZGENE
UniProt Secondary	B2RA98	UniProtKB/Swiss-Prot
	Q5T3Y8	UniProtKB/Swiss-Prot
	Q8TBW6	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM