Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: LYL1 (LYL1 basic helix-loop-helix family member) Homo sapiens
Analyze
Symbol: LYL1
Name: LYL1 basic helix-loop-helix family member
Description: This gene represents a basic helix-loop-helix transcription factor. The encoded protein may play roles in blood vessel maturation and hematopoeisis. A translocation between this locus and the T cell receptor beta locus (GeneID 6957) on chromosome 7 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Sep 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bHLHa18; class A basic helix-loop-helix protein 18; LYL1, basic helix-loop-helix family member; lymphoblastic leukemia associated hematopoiesis regulator 1; lymphoblastic leukemia derived sequence 1; lymphoblastic leukemia-derived sequence 1; protein lyl-1
Orthologs:
Mus musculus (house mouse) : Lyl1 (lymphoblastomic leukemia 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lyl1 (LYL1, basic helix-loop-helix family member)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lyl1 (LYL1 basic helix-loop-helix family member)
Pan paniscus (bonobo/pygmy chimpanzee) : LYL1 (LYL1 basic helix-loop-helix family member)
Canis lupus familiaris (dog) : LYL1 (LYL1 basic helix-loop-helix family member)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lyl1 (LYL1 basic helix-loop-helix family member)
Sus scrofa (pig) : LYL1 (LYL1 basic helix-loop-helix family member)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381913,097,166 - 13,103,751 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371913,208,002 - 13,213,974 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361913,070,847 - 13,074,681 (-)NCBINCBI36hg18NCBI36
Build 341913,070,847 - 13,074,681NCBI
Celera1913,100,251 - 13,104,085 (-)NCBI
Cytogenetic Map19p13.13NCBI
HuRef1912,782,481 - 12,786,613 (-)NCBIHuRef
CHM1_11913,210,856 - 13,214,988 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on LYL1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343769
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.