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Gene: LYL1 (LYL1 basic helix-loop-helix family member) Homo sapiens
Symbol: LYL1
Name: LYL1 basic helix-loop-helix family member
Description: This gene represents a basic helix-loop-helix transcription factor. The encoded protein may play roles in blood vessel maturation and hematopoeisis. A translocation between this locus and the T cell receptor beta locus (GeneID 6957) on chromosome 7 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Sep 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bHLHa18; class A basic helix-loop-helix protein 18; LYL1, basic helix-loop-helix family member; lymphoblastic leukemia associated hematopoiesis regulator 1; lymphoblastic leukemia derived sequence 1; lymphoblastic leukemia-derived sequence 1; protein lyl-1
Mus musculus (house mouse) : Lyl1 (lymphoblastomic leukemia 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lyl1 (LYL1, basic helix-loop-helix family member)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lyl1 (LYL1 basic helix-loop-helix family member)
Pan paniscus (bonobo/pygmy chimpanzee) : LYL1 (LYL1 basic helix-loop-helix family member)
Canis lupus familiaris (dog) : LYL1 (LYL1 basic helix-loop-helix family member)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lyl1 (LYL1 basic helix-loop-helix family member)
Sus scrofa (pig) : LYL1 (LYL1 basic helix-loop-helix family member)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381913,097,166 - 13,103,751 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371913,208,002 - 13,213,974 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361913,070,847 - 13,074,681 (-)NCBINCBI36hg18NCBI36
Build 341913,070,847 - 13,074,681NCBI
Celera1913,100,251 - 13,104,085 (-)NCBI
Cytogenetic Map19p13.13NCBI
HuRef1912,782,481 - 12,786,613 (-)NCBIHuRef
CHM1_11913,210,856 - 13,214,988 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LYL1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343769
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.