Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Ly75 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of LY75 mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | Ly75 (Mus musculus) | 6480464 | Estradiol inhibits the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of LY75 protein] | CTD | PMID:21538406 | 17beta-estradiol | increases expression | ISO | Ly75 (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of LY75 mRNA | CTD | PMID:32145629 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ly75 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of LY75 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Ly75 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LY75 mRNA | CTD | PMID:32109520 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | ISO | Ly75 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:32109520 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Ly75 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of LY75 mRNA | CTD | PMID:18648102 | antirheumatic drug | decreases expression | EXP | | 6480464 | Antirheumatic Agents results in decreased expression of LY75 mRNA | CTD | PMID:24449571 | atrazine | affects methylation | ISO | Ly75 (Rattus norvegicus) | 6480464 | Atrazine affects the methylation of LY75 gene | CTD | PMID:35440735 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of LY75 mRNA | CTD | PMID:20064835 | benzo[a]pyrene | decreases methylation | ISO | Ly75 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of LY75 exon and Benzo(a)pyrene results in decreased methylation of LY75 intron | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of LY75 promoter | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | Ly75 (Mus musculus) | 6480464 | Diethylhexyl Phthalate inhibits the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of LY75 protein] and fulvestrant inhibits the reaction [Diethylhexyl Phthalate inhibits the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of LY75 protein]] | CTD | PMID:21538406 | bisphenol A | affects expression | ISO | Ly75 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of LY75 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | Ly75 (Mus musculus) | 6480464 | bisphenol A results in increased expression of LY75 mRNA | CTD | PMID:33221593 | bisphenol A | increases expression | ISO | Ly75 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of LY75 mRNA | CTD | PMID:32145629 | bisphenol A | decreases expression | ISO | Ly75 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of LY75 mRNA | CTD | PMID:30816183 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to LY75 gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | ISO | Ly75 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of LY75 mRNA | CTD | PMID:37019170 | chromium(6+) | affects expression | ISO | Ly75 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of LY75 mRNA | CTD | PMID:28472532 | clobetasol | decreases expression | ISO | Ly75 (Mus musculus) | 6480464 | Clobetasol results in decreased expression of LY75 protein | CTD | PMID:15086553 | corn oil | increases expression | ISO | Ly75 (Rattus norvegicus) | 6480464 | Corn Oil results in increased expression of LY75 mRNA | CTD | PMID:22760963 | cortisol | decreases expression | ISO | Ly75 (Mus musculus) | 6480464 | Hydrocortisone results in decreased expression of LY75 protein | CTD | PMID:15086553 | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of LY75 mRNA | CTD | PMID:27989131 | cytarabine | increases expression | EXP | | 6480464 | Cytarabine results in increased expression of LY75 mRNA | CTD | PMID:19194470 | diclofenac | increases expression | ISO | Ly75 (Mus musculus) | 6480464 | Diclofenac results in increased expression of LY75 mRNA | CTD | PMID:26934552 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of LY75 mRNA | CTD | PMID:16404146 | endosulfan | decreases expression | ISO | Ly75 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of LY75 mRNA | CTD | PMID:29391264 | entinostat | increases expression | EXP | | 6480464 | entinostat results in increased expression of LY75 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LY75 mRNA | CTD | PMID:27188386 | ethyl methanesulfonate | decreases expression | EXP | | 6480464 | Ethyl Methanesulfonate results in decreased expression of LY75 mRNA | CTD | PMID:23649840 | fentin chloride | increases expression | ISO | Ly75 (Rattus norvegicus) | 6480464 | triphenyltin chloride results in increased expression of LY75 mRNA | CTD | PMID:37156404 | fulvestrant | multiple interactions | ISO | Ly75 (Mus musculus) | 6480464 | fulvestrant inhibits the reaction [Diethylhexyl Phthalate inhibits the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of LY75 protein]] | CTD | PMID:21538406 | genistein | decreases expression | ISO | Ly75 (Mus musculus) | 6480464 | Genistein results in decreased expression of LY75 mRNA | CTD | PMID:32186404 | iron atom | decreases expression | EXP | | 6480464 | Iron deficiency results in decreased expression of LY75 mRNA | CTD | PMID:20368581 | iron(0) | decreases expression | EXP | | 6480464 | Iron deficiency results in decreased expression of LY75 mRNA | CTD | PMID:20368581 | methoxychlor | affects methylation | ISO | Ly75 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of LY75 gene | CTD | PMID:35440735 | methyl methanesulfonate | decreases expression | EXP | | 6480464 | Methyl Methanesulfonate results in decreased expression of LY75 mRNA | CTD | PMID:23649840 | mono(2-ethylhexyl) phthalate | decreases expression | ISO | Ly75 (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of LY75 mRNA | CTD | PMID:22401849 | ozone | multiple interactions | ISO | Ly75 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of LY75 mRNA | CTD | PMID:34911549 | panobinostat | increases expression | EXP | | 6480464 | panobinostat results in increased expression of LY75 mRNA | CTD | PMID:26272509 | panobinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LY75 mRNA | CTD | PMID:27188386 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of LY75 mRNA | CTD | PMID:26690555 | pirinixic acid | multiple interactions | EXP | | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of LY75 mRNA and [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of LY75 mRNA | CTD | PMID:19710929 | pirinixic acid | decreases expression | ISO | Ly75 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of LY75 mRNA | CTD | PMID:20813756 and PMID:23811191 | potassium chromate | decreases expression | EXP | | 6480464 | potassium chromate(VI) results in decreased expression of LY75 mRNA | CTD | PMID:22714537 | resveratrol | multiple interactions | EXP | | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of LY75 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | titanium dioxide | increases expression | ISO | Ly75 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of LY75 mRNA | CTD | PMID:23557971 | trichloroethene | increases expression | ISO | Ly75 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of LY75 mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | EXP | | 6480464 | trichostatin A results in increased expression of LY75 mRNA | CTD | PMID:24935251 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of LY75 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of LY75 mRNA | CTD | PMID:19101580 more ... | vinclozolin | increases expression | ISO | Ly75 (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of LY75 mRNA | CTD | PMID:23869203 | vitamin D | affects expression | EXP | | 6480464 | Vitamin D affects the expression of LY75 mRNA | CTD | PMID:20368581 | |