Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | increases expression | ISO | Dgki (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of DGKI mRNA | CTD | PMID:28960355 | 17alpha-ethynylestradiol | increases expression | ISO | Dgki (Rattus norvegicus) | 6480464 | Ethinyl Estradiol results in increased expression of DGKI mRNA | CTD | PMID:29097150 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of DGKI mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Dgki (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DGKI mRNA | CTD | PMID:32109520 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | ISO | Dgki (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:32109520 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:26705709 | 2-palmitoylglycerol | increases expression | EXP | | 6480464 | 2-palmitoylglycerol results in increased expression of DGKI mRNA | CTD | PMID:37199045 | 6-propyl-2-thiouracil | decreases expression | ISO | Dgki (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of DGKI mRNA | CTD | PMID:24780913 | aflatoxin B1 | decreases methylation | EXP | | 6480464 | Aflatoxin B1 results in decreased methylation of DGKI gene | CTD | PMID:27153756 | aflatoxin B1 | affects methylation | EXP | | 6480464 | Aflatoxin B1 affects the methylation of DGKI intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | increases methylation | EXP | | 6480464 | aflatoxin B2 results in increased methylation of DGKI intron | CTD | PMID:30157460 | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of DGKI mRNA | CTD | PMID:21934132 | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of DGKI mRNA | CTD | PMID:23724009 | ammonium chloride | affects expression | ISO | Dgki (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of DGKI mRNA | CTD | PMID:16483693 | antirheumatic drug | increases expression | EXP | | 6480464 | Antirheumatic Agents results in increased expression of DGKI mRNA | CTD | PMID:24449571 | aristolochic acid A | decreases expression | EXP | | 6480464 | aristolochic acid I results in decreased expression of DGKI mRNA | CTD | PMID:33212167 | arsenite(3-) | affects expression | EXP | | 6480464 | arsenite affects the expression of DGKI mRNA | CTD | PMID:22959463 | arsenous acid | increases expression | EXP | | 6480464 | Arsenic Trioxide results in increased expression of DGKI mRNA | CTD | PMID:20458559 | atrazine | affects methylation | ISO | Dgki (Rattus norvegicus) | 6480464 | Atrazine affects the methylation of DGKI gene | CTD | PMID:35440735 | belinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DGKI mRNA | CTD | PMID:27188386 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of DGKI mRNA | CTD | PMID:22316170 | benzo[a]pyrene | increases methylation | ISO | Dgki (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of DGKI exon | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of DGKI promoter | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | Dgki (Mus musculus) | 6480464 | Benzo(a)pyrene affects the methylation of DGKI intron | CTD | PMID:27901495 | benzo[e]pyrene | increases methylation | EXP | | 6480464 | benzo(e)pyrene results in increased methylation of DGKI intron | CTD | PMID:30157460 | bisphenol A | decreases expression | ISO | Dgki (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of DGKI mRNA | CTD | PMID:25181051 | bisphenol A | increases methylation | ISO | Dgki (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of DGKI gene | CTD | PMID:28505145 | bisphenol A | increases expression | ISO | Dgki (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of DGKI mRNA | CTD | PMID:29097150 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to DGKI gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | ISO | Dgki (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of DGKI mRNA | CTD | PMID:37019170 | copper atom | increases expression | ISO | Dgki (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of DGKI mRNA | CTD | PMID:26033743 | copper(0) | increases expression | ISO | Dgki (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of DGKI mRNA | CTD | PMID:26033743 | Cuprizon | decreases expression | ISO | Dgki (Rattus norvegicus) | 6480464 | Cuprizone results in decreased expression of DGKI mRNA | CTD | PMID:26577399 | dextran sulfate | multiple interactions | ISO | Dgki (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of DGKI mRNA | CTD | PMID:29950665 | diarsenic trioxide | increases expression | EXP | | 6480464 | Arsenic Trioxide results in increased expression of DGKI mRNA | CTD | PMID:20458559 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of DGKI mRNA | CTD | PMID:16404146 | endosulfan | decreases expression | ISO | Dgki (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of DGKI mRNA | CTD | PMID:31464424 | ethanol | affects splicing | ISO | Dgki (Mus musculus) | 6480464 | Ethanol affects the splicing of DGKI mRNA | CTD | PMID:30319688 | ethylparaben | decreases expression | EXP | | 6480464 | ethyl-p-hydroxybenzoate results in decreased expression of DGKI mRNA | CTD | PMID:37690743 | folic acid | decreases expression | ISO | Dgki (Mus musculus) | 6480464 | Folic Acid results in decreased expression of DGKI mRNA | CTD | PMID:25629700 | gentamycin | increases expression | ISO | Dgki (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of DGKI mRNA | CTD | PMID:33387578 | lipopolysaccharide | increases expression | EXP | | 6480464 | Lipopolysaccharides results in increased expression of DGKI mRNA | CTD | PMID:35811015 | lipopolysaccharide | multiple interactions | EXP | | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | maneb | multiple interactions | ISO | Dgki (Mus musculus) | 6480464 | [Paraquat co-treated with Maneb] affects the expression of DGKI mRNA | CTD | PMID:22563483 | mercury dibromide | decreases expression | EXP | | 6480464 | mercuric bromide results in decreased expression of DGKI mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DGKI mRNA | CTD | PMID:27188386 | methapyrilene | increases methylation | EXP | | 6480464 | Methapyrilene results in increased methylation of DGKI intron | CTD | PMID:30157460 | methoxychlor | affects methylation | ISO | Dgki (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of DGKI gene | CTD | PMID:35440735 | mono(2-ethylhexyl) phthalate | increases expression | EXP | | 6480464 | mono-(2-ethylhexyl)phthalate results in increased expression of DGKI mRNA | CTD | PMID:36695872 | N-nitrosodiethylamine | multiple interactions | ISO | Dgki (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in decreased methylation of DGKI promoter and [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of DGKI mRNA | CTD | PMID:25374375 | nickel sulfate | decreases expression | EXP | | 6480464 | nickel sulfate results in decreased expression of DGKI mRNA | CTD | PMID:22714537 | p-chloromercuribenzoic acid | decreases expression | EXP | | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of DGKI mRNA | CTD | PMID:26272509 | p-chloromercuribenzoic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DGKI mRNA | CTD | PMID:27188386 | paraquat | increases expression | ISO | Dgki (Mus musculus) | 6480464 | Paraquat results in increased expression of DGKI mRNA | CTD | PMID:22563483 | paraquat | multiple interactions | ISO | Dgki (Mus musculus) | 6480464 | [Paraquat co-treated with Maneb] affects the expression of DGKI mRNA | CTD | PMID:22563483 | phenobarbital | multiple interactions | ISO | Dgki (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in decreased methylation of DGKI promoter and [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of DGKI mRNA | CTD | PMID:25374375 | phenylmercury acetate | decreases expression | EXP | | 6480464 | Phenylmercuric Acetate results in decreased expression of DGKI mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DGKI mRNA | CTD | PMID:27188386 | potassium chromate | decreases expression | EXP | | 6480464 | potassium chromate(VI) results in decreased expression of DGKI mRNA | CTD | PMID:22714537 | pyridaben | increases expression | ISO | Dgki (Mus musculus) | 6480464 | pyridaben results in increased expression of DGKI mRNA | CTD | PMID:22563483 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | EXP | | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of DGKI mRNA | CTD | PMID:22714537 | sunitinib | decreases expression | EXP | | 6480464 | Sunitinib results in decreased expression of DGKI mRNA | CTD | PMID:31533062 | temozolomide | decreases expression | EXP | | 6480464 | Temozolomide results in decreased expression of DGKI mRNA | CTD | PMID:31758290 | titanium dioxide | multiple interactions | ISO | Dgki (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of DGKI mRNA | CTD | PMID:29950665 | trichloroethene | decreases expression | ISO | Dgki (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased expression of DGKI mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | EXP | | 6480464 | trichostatin A results in decreased expression of DGKI mRNA | CTD | PMID:24935251 | trichostatin A | increases expression | EXP | | 6480464 | trichostatin A results in increased expression of DGKI mRNA | CTD | PMID:24935251 | triclosan | decreases expression | EXP | | 6480464 | Triclosan results in decreased expression of DGKI mRNA | CTD | PMID:30510588 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of DGKI mRNA | CTD | PMID:25979313 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of DGKI mRNA | CTD | PMID:24935251 and PMID:28001369 | vanadium atom | increases expression | EXP | | 6480464 | Vanadium results in increased expression of DGKI mRNA | CTD | PMID:19000753 | vanadium(0) | increases expression | EXP | | 6480464 | Vanadium results in increased expression of DGKI mRNA | CTD | PMID:19000753 | |