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Gene: SATB2 (SATB homeobox 2) Homo sapiens
Symbol: SATB2
Name: SATB homeobox 2
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Predicted to be involved in chromatin remodeling and negative regulation of transcription by RNA polymerase II. Localizes to the nucleoplasm. Implicated in chromosome 2q32-q33 deletion syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DNA-binding protein SATB2; FLJ21474; FLJ32076; GLSS; KIAA1034; MGC119474; MGC119477; SATB family member 2; special AT-rich sequence-binding protein 2
Mus musculus (house mouse) : Satb2 (special AT-rich sequence binding protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Satb2 (SATB homeobox 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Satb2 (SATB homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SATB2 (SATB homeobox 2)
Canis lupus familiaris (dog) : SATB2 (SATB homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Satb2 (SATB homeobox 2)
Sus scrofa (pig) : SATB2 (SATB homeobox 2)
Chlorocebus sabaeus (African green monkey) : SATB2 (SATB homeobox 2)
Heterocephalus glaber (naked mole-rat) : Satb2 (SATB homeobox 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2199,269,500 - 199,471,266 (-)Ensembl
GRCh382199,269,500 - 199,471,266 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372200,134,223 - 200,335,989 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362199,842,469 - 200,033,446 (-)NCBINCBI36hg18NCBI36
Build 342199,959,729 - 200,150,707NCBI
Celera2193,889,754 - 194,091,258 (-)NCBI
Cytogenetic Map2q33.1NCBI
HuRef2191,986,953 - 192,188,680 (-)NCBIHuRef
CHM1_12200,140,433 - 200,341,932 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SATB2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343440
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-02-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.