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Gene: SERPINB2 (serpin family B member 2) Homo sapiens
Symbol: SERPINB2
Name: serpin family B member 2
Description: Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to localize to the extracellular space; PARTICIPATES IN Entamoebiasis pathway; fibrinolysis pathway; INTERACTS WITH (-)-demecolcine; (-)-epigallocatechin 3-gallate; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HsT1201; monocyte Arg-serpin; PAI; PAI-2; PAI2; placental plasminogen activator inhibitor; PLANH2; plasminogen activator inhibitor 2; plasminogen activator inhibitor, type II (arginine-serpin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2; serpin B2; serpin peptidase inhibitor, clade B (ovalbumin), member 2; urokinase inhibitor
Mus musculus (house mouse) : Serpinb2 (serine (or cysteine) peptidase inhibitor, clade B, member 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Serpinb2 (serpin family B member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpinb2 (serpin family B member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINB2 (serpin family B member 2)
Canis lupus familiaris (dog) : SERPINB2 (serpin family B member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpinb2 (serpin family B member 2)
Sus scrofa (pig) : SERPINB2 (serpin family B member 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381863,887,705 - 63,903,890 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371861,554,939 - 61,571,124 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361859,705,922 - 59,722,100 (+)NCBINCBI36hg18NCBI36
Build 341859,705,921 - 59,722,100NCBI
Celera1858,275,397 - 58,291,583 (+)NCBI
Cytogenetic Map18q21.33-q22.1NCBI
HuRef1858,256,074 - 58,272,260 (+)NCBIHuRef
CHM1_11861,551,138 - 61,567,323 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SERPINB2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343432
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.