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Gene: SERPINB2 (serpin family B member 2) Homo sapiens
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Symbol: SERPINB2
Name: serpin family B member 2
Description: Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to localize to the extracellular space; PARTICIPATES IN Entamoebiasis pathway; fibrinolysis pathway; INTERACTS WITH (-)-demecolcine; (-)-epigallocatechin 3-gallate; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HsT1201; monocyte Arg-serpin; PAI; PAI-2; PAI2; placental plasminogen activator inhibitor; PLANH2; plasminogen activator inhibitor 2; plasminogen activator inhibitor, type II (arginine-serpin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2; serpin B2; serpin peptidase inhibitor, clade B (ovalbumin), member 2; urokinase inhibitor
Orthologs:
Mus musculus (house mouse) : Serpinb2 (serine (or cysteine) peptidase inhibitor, clade B, member 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Serpinb2 (serpin family B member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpinb2 (serpin family B member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINB2 (serpin family B member 2)
Canis lupus familiaris (dog) : SERPINB2 (serpin family B member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpinb2 (serpin family B member 2)
Sus scrofa (pig) : SERPINB2 (serpin family B member 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381863,887,705 - 63,903,890 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371861,554,939 - 61,571,124 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361859,705,922 - 59,722,100 (+)NCBINCBI36hg18NCBI36
Build 341859,705,921 - 59,722,100NCBI
Celera1858,275,397 - 58,291,583 (+)NCBI
Cytogenetic Map18q21.33-q22.1NCBI
HuRef1858,256,074 - 58,272,260 (+)NCBIHuRef
CHM1_11861,551,138 - 61,567,323 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SERPINB2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343432
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.