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Gene: KLF3 (Kruppel like factor 3) Homo sapiens
Symbol: KLF3
Name: Kruppel like factor 3
Description: Exhibits sequence-specific double-stranded DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Localizes to nucleoplasm; INTERACTS WITH aflatoxin B1; all-trans-retinoic acid; arsenous acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: basic krueppel-like factor; basic kruppel like factor; basic Kruppel-like factor; BKLF; CACCC-box-binding protein BKLF; Krueppel-like factor 3; Kruppel-like factor 3 (basic); MGC48279; TEF-2; transcript ch138
Mus musculus (house mouse) : Klf3 (Kruppel-like factor 3 (basic))  MGI  Alliance
Rattus norvegicus (Norway rat) : Klf3 (Kruppel like factor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klf3 (Kruppel like factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : KLF3 (Kruppel like factor 3)
Canis lupus familiaris (dog) : KLF3 (Kruppel like factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klf3 (Kruppel like factor 3)
Sus scrofa (pig) : KLF3 (Kruppel like factor 3)
Chlorocebus sabaeus (African green monkey) : KLF3 (Kruppel like factor 3)
Heterocephalus glaber (naked mole-rat) : Klf3 (Kruppel like factor 3)
more info ...
Related Pseudogenes: KLF3P1   KLF3P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl438,664,197 - 38,701,517 (+)EnsemblGRCh38hg38GRCh38
GRCh38438,664,079 - 38,701,517 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37438,665,790 - 38,703,129 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36438,342,185 - 38,379,524 (+)NCBINCBI36hg18NCBI36
Build 34438,488,388 - 38,522,964NCBI
Celera439,107,001 - 39,144,340 (+)NCBI
Cytogenetic Map4p14NCBI
HuRef437,989,129 - 38,026,462 (+)NCBIHuRef
CHM1_1438,664,914 - 38,702,230 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KLF3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343244
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.