Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SFXN5 mRNA] | CTD | PMID:31150632 | 1,1-dichloroethene | decreases expression | ISO | Sfxn5 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of SFXN5 mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | decreases expression | ISO | Sfxn5 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SFXN5 mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Sfxn5 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SFXN5 mRNA | CTD | PMID:21570461 and PMID:24680724 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SFXN5 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Sfxn5 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SFXN5 mRNA | CTD | PMID:28213091 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of SFXN5 mRNA | CTD | PMID:30071829 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Sfxn5 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of SFXN5 mRNA | CTD | PMID:18648102 | acrolein | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of SFXN5 mRNA more ... | CTD | PMID:32699268 and PMID:32845096 | acrylamide | decreases expression | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | Acrylamide results in decreased expression of SFXN5 mRNA | CTD | PMID:28959563 | acrylamide | decreases expression | ISO | Sfxn5 (Mus musculus) | 6480464 | Acrylamide results in decreased expression of SFXN5 mRNA | CTD | PMID:30807115 | aflatoxin B1 | decreases expression | ISO | Sfxn5 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of SFXN5 mRNA | CTD | PMID:19770486 | aflatoxin B1 | decreases expression | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | Aflatoxin B1 results in decreased expression of SFXN5 mRNA | CTD | PMID:33354967 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of SFXN5 mRNA | CTD | PMID:22100608 | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of SFXN5 mRNA | CTD | PMID:33167477 | alpha-pinene | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of SFXN5 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of SFXN5 mRNA | CTD | PMID:32699268 | antirheumatic drug | increases expression | EXP | | 6480464 | Antirheumatic Agents results in increased expression of SFXN5 mRNA | CTD | PMID:24449571 | benzo[a]pyrene | decreases expression | ISO | Sfxn5 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of SFXN5 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of SFXN5 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of SFXN5 promoter | CTD | PMID:27901495 | bisphenol A | decreases expression | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of SFXN5 mRNA | CTD | PMID:25181051 and PMID:30816183 | butanal | decreases expression | EXP | | 6480464 | butyraldehyde results in decreased expression of SFXN5 mRNA | CTD | PMID:26079696 | carbon nanotube | decreases expression | ISO | Sfxn5 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | carbon nanotube | increases expression | ISO | Sfxn5 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SFXN5 gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | ISO | Sfxn5 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of SFXN5 mRNA | CTD | PMID:37019170 | chlorpyrifos | decreases expression | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | Chlorpyrifos results in decreased expression of SFXN5 protein | CTD | PMID:34058248 | cisplatin | multiple interactions | EXP | | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of SFXN5 mRNA | CTD | PMID:27392435 | cisplatin | increases expression | EXP | | 6480464 | Cisplatin results in increased expression of SFXN5 mRNA | CTD | PMID:27392435 | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of SFXN5 mRNA | CTD | PMID:20106945 | dexamethasone | decreases expression | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | Dexamethasone results in decreased expression of SFXN5 mRNA | CTD | PMID:20032058 | dexamethasone | multiple interactions | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of SFXN5 mRNA] | CTD | PMID:20032058 | diazinon | increases methylation | EXP | | 6480464 | Diazinon results in increased methylation of SFXN5 gene | CTD | PMID:22964155 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | endosulfan | increases expression | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of SFXN5 mRNA | CTD | PMID:29391264 | ethanol | increases expression | ISO | Sfxn5 (Mus musculus) | 6480464 | Ethanol results in increased expression of SFXN5 mRNA | CTD | PMID:30319688 | ethanol | affects splicing | ISO | Sfxn5 (Mus musculus) | 6480464 | Ethanol affects the splicing of SFXN5 mRNA | CTD | PMID:30319688 | fenthion | decreases expression | ISO | Sfxn5 (Mus musculus) | 6480464 | Fenthion results in decreased expression of SFXN5 mRNA | CTD | PMID:34813904 | folic acid | increases expression | ISO | Sfxn5 (Mus musculus) | 6480464 | Folic Acid results in increased expression of SFXN5 mRNA | CTD | PMID:25629700 | leflunomide | decreases expression | EXP | | 6480464 | leflunomide results in decreased expression of SFXN5 mRNA | CTD | PMID:28988120 and PMID:29427785 | manganese atom | increases expression | EXP | | 6480464 | Manganese results in increased expression of SFXN5 mRNA | CTD | PMID:17175027 | manganese(0) | increases expression | EXP | | 6480464 | Manganese results in increased expression of SFXN5 mRNA | CTD | PMID:17175027 | manganese(II) chloride | increases expression | EXP | | 6480464 | manganese chloride results in increased expression of SFXN5 mRNA | CTD | PMID:17175027 | mercury dibromide | increases expression | EXP | | 6480464 | mercuric bromide results in increased expression of SFXN5 mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SFXN5 mRNA | CTD | PMID:27188386 | mercury dichloride | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SFXN5 mRNA | CTD | PMID:27188386 | methidathion | decreases expression | ISO | Sfxn5 (Mus musculus) | 6480464 | methidathion results in decreased expression of SFXN5 mRNA | CTD | PMID:34813904 | methoxychlor | affects methylation | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of SFXN5 gene | CTD | PMID:35440735 | methyl methanesulfonate | increases expression | EXP | | 6480464 | Methyl Methanesulfonate results in increased expression of SFXN5 mRNA | CTD | PMID:23649840 | ozone | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of SFXN5 mRNA more ... | CTD | PMID:32699268 more ... | p-chloromercuribenzoic acid | increases expression | EXP | | 6480464 | p-Chloromercuribenzoic Acid results in increased expression of SFXN5 mRNA | CTD | PMID:26272509 | p-chloromercuribenzoic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SFXN5 mRNA | CTD | PMID:27188386 | paracetamol | affects expression | ISO | Sfxn5 (Mus musculus) | 6480464 | Acetaminophen affects the expression of SFXN5 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of SFXN5 mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of SFXN5 mRNA | CTD | PMID:32479839 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SFXN5 mRNA | CTD | PMID:22230336 | perfluorononanoic acid | decreases expression | EXP | | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of SFXN5 mRNA | CTD | PMID:32588087 | phenobarbital | multiple interactions | ISO | Sfxn5 (Mus musculus) | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of SFXN5 mRNA] | CTD | PMID:19482888 | phenobarbital | decreases expression | ISO | Sfxn5 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of SFXN5 mRNA | CTD | PMID:19482888 | phenylmercury acetate | increases expression | EXP | | 6480464 | Phenylmercuric Acetate results in increased expression of SFXN5 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SFXN5 mRNA | CTD | PMID:27188386 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sunitinib | decreases expression | EXP | | 6480464 | Sunitinib results in decreased expression of SFXN5 mRNA | CTD | PMID:31533062 | temozolomide | increases expression | EXP | | 6480464 | Temozolomide results in increased expression of SFXN5 mRNA | CTD | PMID:31758290 | testosterone | multiple interactions | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of SFXN5 mRNA] | CTD | PMID:20032058 | tetrachloromethane | multiple interactions | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SFXN5 mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | ISO | Sfxn5 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of SFXN5 mRNA | CTD | PMID:31919559 | tetrachloromethane | decreases expression | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of SFXN5 mRNA | CTD | PMID:31150632 | thioacetamide | decreases expression | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of SFXN5 mRNA | CTD | PMID:23411599 and PMID:34492290 | trichloroethene | increases expression | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of SFXN5 mRNA | CTD | PMID:33387578 | triphenyl phosphate | increases expression | ISO | Sfxn5 (Rattus norvegicus) | 6480464 | triphenyl phosphate results in increased expression of SFXN5 mRNA | CTD | PMID:30589522 | tunicamycin | increases expression | EXP | | 6480464 | Tunicamycin results in increased expression of SFXN5 mRNA | CTD | PMID:22378314 | urethane | decreases expression | EXP | | 6480464 | Urethane results in decreased expression of SFXN5 mRNA | CTD | PMID:28818685 | |