KCNJ16 (potassium inwardly rectifying channel subfamily J member 16) - Rat Genome Database

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Gene: KCNJ16 (potassium inwardly rectifying channel subfamily J member 16) Homo sapiens
Analyze
Symbol: KCNJ16
Name: potassium inwardly rectifying channel subfamily J member 16
RGD ID: 1343172
HGNC Page HGNC:6262
Description: Predicted to enable inward rectifier potassium channel activity. Predicted to be involved in potassium ion import across plasma membrane and regulation of monoatomic ion transmembrane transport. Predicted to be located in basolateral plasma membrane. Predicted to be part of monoatomic ion channel complex. Predicted to be active in plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: BIR9; HKTD; inward rectifier K(+) channel Kir5.1; inward rectifier K+ channel KIR5.1; inward rectifier potassium channel 16; KIR5.1; MGC33717; potassium channel, inwardly rectifying subfamily J member 16; potassium channel, inwardly rectifying subfamily J, member 16; potassium inwardly-rectifying channel, subfamily J, member 16; potassium voltage-gated channel subfamily J member 16
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381770,075,225 - 70,135,608 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1770,053,429 - 70,135,608 (+)EnsemblGRCh38hg38GRCh38
GRCh371768,071,366 - 68,131,749 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361765,583,021 - 65,643,344 (+)NCBINCBI36Build 36hg18NCBI36
Build 341765,612,589 - 65,643,339NCBI
Celera1764,643,318 - 64,703,632 (+)NCBICelera
Cytogenetic Map17q24.3NCBI
HuRef1763,457,561 - 63,518,274 (+)NCBIHuRef
CHM1_11768,137,477 - 68,197,868 (+)NCBICHM1_1
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Essential role of Kir5.1 channels in renal salt handling and blood pressure control. Palygin O, etal., JCI Insight. 2017 Sep 21;2(18). pii: 92331. doi: 10.1172/jci.insight.92331. eCollection 2017 Sep 21.
3. Genetic mutation of Kcnj16 identifies Kir5.1-containing channels as key regulators of acute and chronic pH homeostasis. Puissant MM, etal., FASEB J. 2019 Apr;33(4):5067-5075. doi: 10.1096/fj.201802257R. Epub 2019 Jan 3.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8125298   PMID:9882736   PMID:11060447   PMID:11240146   PMID:11306656   PMID:11988170   PMID:12456399   PMID:12477932   PMID:12923169   PMID:16344560   PMID:16382105   PMID:17185339  
PMID:18391953   PMID:19234473   PMID:19240061   PMID:20379614   PMID:20881960   PMID:21873635   PMID:22436252   PMID:22863731   PMID:22907060   PMID:23362303   PMID:23704328   PMID:23873931  
PMID:24024966   PMID:24193250   PMID:24559202   PMID:25339316   PMID:26663529   PMID:27599582   PMID:28577853   PMID:29897283   PMID:33811157   PMID:35809813   PMID:35848616  


Genomics

Comparative Map Data
KCNJ16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381770,075,225 - 70,135,608 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1770,053,429 - 70,135,608 (+)EnsemblGRCh38hg38GRCh38
GRCh371768,071,366 - 68,131,749 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361765,583,021 - 65,643,344 (+)NCBINCBI36Build 36hg18NCBI36
Build 341765,612,589 - 65,643,339NCBI
Celera1764,643,318 - 64,703,632 (+)NCBICelera
Cytogenetic Map17q24.3NCBI
HuRef1763,457,561 - 63,518,274 (+)NCBIHuRef
CHM1_11768,137,477 - 68,197,868 (+)NCBICHM1_1
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBIT2T-CHM13v2.0
Kcnj16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911110,858,859 - 110,918,794 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11110,858,859 - 110,918,794 (+)EnsemblGRCm39 Ensembl
GRCm3811110,968,033 - 111,027,968 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11110,968,033 - 111,027,968 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711110,829,347 - 110,889,282 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611110,835,677 - 110,844,058 (+)NCBIMGSCv36mm8
Celera11122,716,155 - 122,778,458 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1175.01NCBI
Kcnj16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21095,990,009 - 96,021,356 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1095,960,725 - 96,021,702 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10101,081,523 - 101,083,303 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010100,544,500 - 100,546,280 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01095,952,661 - 95,954,441 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01099,330,894 - 99,391,551 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1099,388,130 - 99,389,898 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01099,027,026 - 99,087,674 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410100,514,180 - 100,515,949 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110100,528,549 - 100,530,318 (+)NCBI
Celera1094,663,783 - 94,665,552 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
Kcnj16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554782,775,702 - 2,802,501 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554782,775,702 - 2,833,821 (-)NCBIChiLan1.0ChiLan1.0
KCNJ16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11790,946,509 - 90,978,647 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01764,005,085 - 64,065,153 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11769,389,581 - 69,449,593 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1769,411,032 - 69,447,343 (+)Ensemblpanpan1.1panPan2
KCNJ16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1916,369,312 - 16,441,953 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl916,383,702 - 16,441,953 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha917,274,785 - 17,333,030 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0918,023,819 - 18,096,162 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl918,038,198 - 18,096,041 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1916,982,418 - 17,040,164 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0910,494,745 - 10,552,754 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0910,460,571 - 10,518,835 (-)NCBIUU_Cfam_GSD_1.0
Kcnj16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056029,989,581 - 10,013,038 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366553,488,338 - 3,489,597 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366553,487,071 - 3,489,686 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNJ16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1210,393,179 - 10,558,169 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11210,393,172 - 10,538,423 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KCNJ16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11651,491,064 - 51,631,037 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1651,493,340 - 51,494,596 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607722,382,841 - 22,554,086 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnj16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624801269,533 - 335,535 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624801269,449 - 335,535 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in KCNJ16
22 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17q24.3(chr17:69766783-71154921)x1 copy number loss See cases [RCV000051104] Chr17:69766783..71154921 [GRCh38]
Chr17:67762924..69151062 [GRCh37]
Chr17:65274519..66662657 [NCBI36]
Chr17:17q24.3
uncertain significance
GRCh38/hg38 17q24.3-25.3(chr17:69209079-83086677)x3 copy number gain See cases [RCV000052486] Chr17:69209079..83086677 [GRCh38]
Chr17:67205220..81044553 [GRCh37]
Chr17:64716815..78637842 [NCBI36]
Chr17:17q24.3-25.3
pathogenic
GRCh38/hg38 17q23.2-25.3(chr17:36449220-83086677)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|See cases [RCV000052483] Chr17:36449220..83086677 [GRCh38]
Chr17:58617905..81044553 [GRCh37]
Chr17:55972687..78637842 [NCBI36]
Chr17:17q23.2-25.3
pathogenic
GRCh38/hg38 17q24.2-24.3(chr17:67833866-70085854)x1 copy number loss See cases [RCV000053452] Chr17:67833866..70085854 [GRCh38]
Chr17:65829982..68081995 [GRCh37]
Chr17:63260444..65593590 [NCBI36]
Chr17:17q24.2-24.3
pathogenic
GRCh38/hg38 17q24.3(chr17:70093968-70709796)x3 copy number gain See cases [RCV000054046] Chr17:70093968..70709796 [GRCh38]
Chr17:68090109..68705937 [GRCh37]
Chr17:65601704..66217532 [NCBI36]
Chr17:17q24.3
uncertain significance
NM_018658.2(KCNJ16):c.315G>A (p.Trp105Ter) single nucleotide variant Malignant melanoma [RCV000071644] Chr17:70132297 [GRCh38]
Chr17:68128438 [GRCh37]
Chr17:65640033 [NCBI36]
Chr17:17q24.3
not provided
NM_018658.2(KCNJ16):c.899C>T (p.Ala300Val) single nucleotide variant Malignant melanoma [RCV000063289] Chr17:70132881 [GRCh38]
Chr17:68129022 [GRCh37]
Chr17:65640617 [NCBI36]
Chr17:17q24.3
not provided
GRCh38/hg38 17q23.1-25.1(chr17:36449220-75053130)x3 copy number gain See cases [RCV000137437] Chr17:36449220..75053130 [GRCh38]
Chr17:57595736..73049225 [GRCh37]
Chr17:54950518..70560820 [NCBI36]
Chr17:17q23.1-25.1
pathogenic
GRCh38/hg38 17q24.3(chr17:70089117-71111424)x3 copy number gain See cases [RCV000141126] Chr17:70089117..71111424 [GRCh38]
Chr17:68085258..69107565 [GRCh37]
Chr17:65596853..66619160 [NCBI36]
Chr17:17q24.3
likely benign|uncertain significance
GRCh38/hg38 17q24.2-24.3(chr17:68420514-71351235)x1 copy number loss See cases [RCV000143113] Chr17:68420514..71351235 [GRCh38]
Chr17:66416655..69347376 [GRCh37]
Chr17:63928250..66858971 [NCBI36]
Chr17:17q24.2-24.3
pathogenic
GRCh38/hg38 17q24.3-25.3(chr17:69916435-83102552)x3 copy number gain See cases [RCV000143342] Chr17:69916435..83102552 [GRCh38]
Chr17:67912576..81048189 [GRCh37]
Chr17:65424171..78653717 [NCBI36]
Chr17:17q24.3-25.3
pathogenic
GRCh37/hg19 17q24.2-24.3(chr17:65343022-69344022)x3 copy number gain See cases [RCV000446484] Chr17:65343022..69344022 [GRCh37]
Chr17:17q24.2-24.3
uncertain significance
GRCh37/hg19 17q24.2-25.3(chr17:64241326-81041938)x3 copy number gain See cases [RCV000447577] Chr17:64241326..81041938 [GRCh37]
Chr17:17q24.2-25.3
pathogenic
GRCh37/hg19 17q21.31-25.3(chr17:42580684-81085615)x3 copy number gain See cases [RCV000447823] Chr17:42580684..81085615 [GRCh37]
Chr17:17q21.31-25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
NM_170741.4(KCNJ16):c.-191+1= single nucleotide variant not specified [RCV000603542] Chr17:70100767 [GRCh38]
Chr17:68096908 [GRCh37]
Chr17:17q24.3
benign
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17q24.2-25.3(chr17:67002415-81041938)x3 copy number gain See cases [RCV000512573] Chr17:67002415..81041938 [GRCh37]
Chr17:17q24.2-25.3
pathogenic
GRCh37/hg19 17q24.3(chr17:67671686-70691445)x3 copy number gain not provided [RCV000683956] Chr17:67671686..70691445 [GRCh37]
Chr17:17q24.3
uncertain significance
GRCh37/hg19 17q24.1-25.3(chr17:63689671-81041938)x3 copy number gain not provided [RCV000683952] Chr17:63689671..81041938 [GRCh37]
Chr17:17q24.1-25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
NM_170741.4(KCNJ16):c.-94+77C>T single nucleotide variant not provided [RCV001530790] Chr17:70131052 [GRCh38]
Chr17:68127193 [GRCh37]
Chr17:17q24.3
benign
GRCh37/hg19 17q24.1-25.2(chr17:64159738-74891024)x3 copy number gain not provided [RCV000762750] Chr17:64159738..74891024 [GRCh37]
Chr17:17q24.1-25.2
likely pathogenic
NM_170741.4(KCNJ16):c.409C>G (p.Arg137Gly) single nucleotide variant not provided [RCV003312402] Chr17:70132496 [GRCh38]
Chr17:68128637 [GRCh37]
Chr17:17q24.3
likely pathogenic
NM_170741.4(KCNJ16):c.1233A>G (p.Arg411=) single nucleotide variant not provided [RCV000972542] Chr17:70133320 [GRCh38]
Chr17:68129461 [GRCh37]
Chr17:17q24.3
benign
GRCh37/hg19 17q24.3(chr17:68056381-68268736)x1 copy number loss not provided [RCV001006915] Chr17:68056381..68268736 [GRCh37]
Chr17:17q24.3
likely pathogenic
GRCh37/hg19 17q24.1-25.3(chr17:62778720-81041938)x3 copy number gain not provided [RCV000849900] Chr17:62778720..81041938 [GRCh37]
Chr17:17q24.1-25.3
pathogenic
NM_170741.4(KCNJ16):c.-94+234dup duplication not provided [RCV001682316] Chr17:70131194..70131195 [GRCh38]
Chr17:68127335..68127336 [GRCh37]
Chr17:17q24.3
benign
NM_170741.4(KCNJ16):c.-191+7733A>C single nucleotide variant not provided [RCV001616525] Chr17:70108499 [GRCh38]
Chr17:68104640 [GRCh37]
Chr17:17q24.3
benign
NC_000017.11:g.70075206C>T single nucleotide variant not provided [RCV001714093] Chr17:70075206 [GRCh38]
Chr17:68071347 [GRCh37]
Chr17:17q24.3
benign
NM_170741.4(KCNJ16):c.672A>C (p.Thr224=) single nucleotide variant not provided [RCV001620695] Chr17:70132759 [GRCh38]
Chr17:68128900 [GRCh37]
Chr17:17q24.3
benign
NM_170741.4(KCNJ16):c.-190-229A>G single nucleotide variant not provided [RCV001717517] Chr17:70130650 [GRCh38]
Chr17:68126791 [GRCh37]
Chr17:17q24.3
benign
NM_170741.4(KCNJ16):c.-94+234del deletion not provided [RCV001608197] Chr17:70131195 [GRCh38]
Chr17:68127336 [GRCh37]
Chr17:17q24.3
benign
NM_170741.4(KCNJ16):c.526C>T (p.Arg176Ter) single nucleotide variant Hypokalemic tubulopathy and deafness [RCV001528162] Chr17:70132613 [GRCh38]
Chr17:68128754 [GRCh37]
Chr17:17q24.3
pathogenic
NM_170741.4(KCNJ16):c.31A>G (p.Ile11Val) single nucleotide variant not provided [RCV001675371] Chr17:70132118 [GRCh38]
Chr17:68128259 [GRCh37]
Chr17:17q24.3
benign
NM_170741.4(KCNJ16):c.-299-141T>C single nucleotide variant not provided [RCV001684193] Chr17:70100517 [GRCh38]
Chr17:68096658 [GRCh37]
Chr17:17q24.3
benign
NM_170741.4(KCNJ16):c.-94+74T>A single nucleotide variant not provided [RCV001713208] Chr17:70131049 [GRCh38]
Chr17:68127190 [GRCh37]
Chr17:17q24.3
benign
NM_170741.4(KCNJ16):c.*150del deletion not provided [RCV001713209] Chr17:70133494 [GRCh38]
Chr17:68129635 [GRCh37]
Chr17:17q24.3
benign
NM_170741.4(KCNJ16):c.191C>T (p.Thr64Ile) single nucleotide variant Hypokalemic tubulopathy and deafness [RCV001528166] Chr17:70132278 [GRCh38]
Chr17:68128419 [GRCh37]
Chr17:17q24.3
pathogenic
NM_170741.4(KCNJ16):c.404G>C (p.Gly135Ala) single nucleotide variant Hypokalemic tubulopathy and deafness [RCV001528165] Chr17:70132491 [GRCh38]
Chr17:68128632 [GRCh37]
Chr17:17q24.3
pathogenic
NM_170741.4(KCNJ16):c.749C>T (p.Pro250Leu) single nucleotide variant Hypokalemic tubulopathy and deafness [RCV001528164] Chr17:70132836 [GRCh38]
Chr17:68128977 [GRCh37]
Chr17:17q24.3
pathogenic
NM_170741.4(KCNJ16):c.409C>T (p.Arg137Cys) single nucleotide variant Hypokalemic tubulopathy and deafness [RCV001528161] Chr17:70132496 [GRCh38]
Chr17:68128637 [GRCh37]
Chr17:17q24.3
pathogenic
NM_170741.4(KCNJ16):c.395T>G (p.Ile132Arg) single nucleotide variant Hypokalemic tubulopathy and deafness [RCV001528163] Chr17:70132482 [GRCh38]
Chr17:68128623 [GRCh37]
Chr17:17q24.3
pathogenic
NM_170741.4(KCNJ16):c.-191+7669G>A single nucleotide variant not provided [RCV001686982] Chr17:70108435 [GRCh38]
Chr17:68104576 [GRCh37]
Chr17:17q24.3
benign
NM_170741.4(KCNJ16):c.-94+218_-94+219insA insertion not provided [RCV001794693] Chr17:70131193..70131194 [GRCh38]
Chr17:68127334..68127335 [GRCh37]
Chr17:17q24.3
benign
NM_170741.4(KCNJ16):c.-94+219C>A single nucleotide variant not provided [RCV001767963] Chr17:70131194 [GRCh38]
Chr17:68127335 [GRCh37]
Chr17:17q24.3
likely benign
NM_170741.4(KCNJ16):c.-190-164A>G single nucleotide variant not provided [RCV002285596] Chr17:70130715 [GRCh38]
Chr17:68126856 [GRCh37]
Chr17:17q24.3
likely benign
GRCh37/hg19 17q24.3(chr17:67730594-68272354)x3 copy number gain not provided [RCV002474726] Chr17:67730594..68272354 [GRCh37]
Chr17:17q24.3
uncertain significance
NM_170741.4(KCNJ16):c.467T>G (p.Leu156Ter) single nucleotide variant KCNJ16-related condition [RCV003422437] Chr17:70132554 [GRCh38]
Chr17:68128695 [GRCh37]
Chr17:17q24.3
likely pathogenic
NM_170741.4(KCNJ16):c.397_399dup (p.Gly133_Tyr134insGly) duplication KCNJ16-related condition [RCV003400166] Chr17:70132482..70132483 [GRCh38]
Chr17:68128623..68128624 [GRCh37]
Chr17:17q24.3
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4379
Count of miRNA genes:791
Interacting mature miRNAs:899
Transcripts:ENST00000283936, ENST00000392670, ENST00000392671, ENST00000585558, ENST00000586462, ENST00000587698, ENST00000587892, ENST00000588112, ENST00000589377, ENST00000591891
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH46249  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371768,131,554 - 68,131,719UniSTSGRCh37
Build 361765,643,149 - 65,643,314RGDNCBI36
Celera1764,703,437 - 64,703,602RGD
Cytogenetic Map17q24.3UniSTS
HuRef1763,518,079 - 63,518,244UniSTS
GeneMap99-GB4 RH Map17448.77UniSTS
NCBI RH Map17711.8UniSTS
KCNJ16_878  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371768,129,167 - 68,129,982UniSTSGRCh37
Build 361765,640,762 - 65,641,577RGDNCBI36
Celera1764,701,047 - 64,701,862RGD
HuRef1763,515,689 - 63,516,504UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 204 716 29 10 13 79 612 302 46 716 17 79
Low 249 30 472 362 223 231 819 175 2922 19 418 295 130 306 622 1
Below cutoff 1755 2366 449 164 765 150 3025 1865 104 52 843 405 14 890 1878 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001270422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_018658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_170741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_170742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005257337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006721885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006721886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006721887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011524781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017024609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017024610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047435950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047435951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047435952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047435953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047435954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047435955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047435956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047435957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047435958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC005208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF153815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF153816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF153817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF179353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH009401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK225944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC030961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC033038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA071381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA109745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA128508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA627411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA628604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA636394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF459700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENST00000283936   ⟹   ENSP00000283936
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1770,075,225 - 70,135,603 (+)Ensembl
RefSeq Acc Id: ENST00000392670   ⟹   ENSP00000376438
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1770,104,854 - 70,135,603 (+)Ensembl
RefSeq Acc Id: ENST00000392671   ⟹   ENSP00000376439
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1770,075,225 - 70,135,608 (+)Ensembl
RefSeq Acc Id: ENST00000585558   ⟹   ENSP00000465295
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1770,104,854 - 70,135,608 (+)Ensembl
RefSeq Acc Id: ENST00000586462   ⟹   ENSP00000467568
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1770,096,640 - 70,133,604 (+)Ensembl
RefSeq Acc Id: ENST00000587698   ⟹   ENSP00000466132
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1770,104,998 - 70,132,280 (+)Ensembl
RefSeq Acc Id: ENST00000587892   ⟹   ENSP00000465163
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1770,105,000 - 70,132,194 (+)Ensembl
RefSeq Acc Id: ENST00000588112
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1770,075,246 - 70,102,210 (+)Ensembl
RefSeq Acc Id: ENST00000589377   ⟹   ENSP00000465967
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1770,075,321 - 70,135,608 (+)Ensembl
RefSeq Acc Id: ENST00000591891   ⟹   ENSP00000465646
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1770,053,429 - 70,132,193 (+)Ensembl
RefSeq Acc Id: ENST00000615244   ⟹   ENSP00000479817
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1770,075,225 - 70,135,603 (+)Ensembl
RefSeq Acc Id: NM_001270422   ⟹   NP_001257351
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
GRCh371768,071,348 - 68,131,749 (+)NCBI
HuRef1763,457,561 - 63,518,274 (+)NCBI
CHM1_11768,137,477 - 68,197,868 (+)NCBI
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001291622   ⟹   NP_001278551
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
CHM1_11768,137,477 - 68,197,868 (+)NCBI
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001291623   ⟹   NP_001278552
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,104,998 - 70,135,608 (+)NCBI
CHM1_11768,167,111 - 68,197,868 (+)NCBI
T2T-CHM13v2.01770,983,325 - 71,013,930 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001291624   ⟹   NP_001278553
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,104,845 - 70,135,608 (+)NCBI
CHM1_11768,167,111 - 68,197,868 (+)NCBI
T2T-CHM13v2.01770,983,173 - 71,013,930 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001291625   ⟹   NP_001278554
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,104,845 - 70,135,608 (+)NCBI
CHM1_11768,167,111 - 68,197,868 (+)NCBI
T2T-CHM13v2.01770,983,173 - 71,013,930 (+)NCBI
Sequence:
RefSeq Acc Id: NM_018658   ⟹   NP_061128
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
GRCh371768,071,348 - 68,131,749 (+)NCBI
Build 361765,583,021 - 65,643,344 (+)NCBI Archive
Celera1764,643,318 - 64,703,632 (+)RGD
HuRef1763,457,561 - 63,518,274 (+)NCBI
CHM1_11768,137,477 - 68,197,868 (+)NCBI
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
Sequence:
RefSeq Acc Id: NM_170741   ⟹   NP_733937
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
GRCh371768,071,348 - 68,131,749 (+)NCBI
Build 361765,583,021 - 65,643,344 (+)NCBI Archive
Celera1764,643,318 - 64,703,632 (+)RGD
HuRef1763,457,561 - 63,518,274 (+)NCBI
CHM1_11768,137,477 - 68,197,868 (+)NCBI
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
Sequence:
RefSeq Acc Id: NM_170742   ⟹   NP_733938
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,104,998 - 70,135,608 (+)NCBI
GRCh371768,071,348 - 68,131,749 (+)NCBI
Build 361765,612,590 - 65,643,344 (+)NCBI Archive
Celera1764,643,318 - 64,703,632 (+)RGD
CHM1_11768,167,111 - 68,197,868 (+)NCBI
T2T-CHM13v2.01770,983,325 - 71,013,930 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005257337   ⟹   XP_005257394
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006721886   ⟹   XP_006721949
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006721887   ⟹   XP_006721950
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011524781   ⟹   XP_011523083
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017024609   ⟹   XP_016880098
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017024610   ⟹   XP_016880099
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047435950   ⟹   XP_047291906
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
RefSeq Acc Id: XM_047435951   ⟹   XP_047291907
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
RefSeq Acc Id: XM_047435952   ⟹   XP_047291908
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
RefSeq Acc Id: XM_047435953   ⟹   XP_047291909
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
RefSeq Acc Id: XM_047435954   ⟹   XP_047291910
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
RefSeq Acc Id: XM_047435955   ⟹   XP_047291911
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
RefSeq Acc Id: XM_047435956   ⟹   XP_047291912
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
RefSeq Acc Id: XM_047435957   ⟹   XP_047291913
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,225 - 70,135,608 (+)NCBI
RefSeq Acc Id: XM_047435958   ⟹   XP_047291914
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,127,149 - 70,135,608 (+)NCBI
RefSeq Acc Id: XM_054316006   ⟹   XP_054171981
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
RefSeq Acc Id: XM_054316007   ⟹   XP_054171982
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
RefSeq Acc Id: XM_054316008   ⟹   XP_054171983
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
RefSeq Acc Id: XM_054316009   ⟹   XP_054171984
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
RefSeq Acc Id: XM_054316010   ⟹   XP_054171985
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
RefSeq Acc Id: XM_054316011   ⟹   XP_054171986
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
RefSeq Acc Id: XM_054316012   ⟹   XP_054171987
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
RefSeq Acc Id: XM_054316013   ⟹   XP_054171988
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
RefSeq Acc Id: XM_054316014   ⟹   XP_054171989
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
RefSeq Acc Id: XM_054316015   ⟹   XP_054171990
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
RefSeq Acc Id: XM_054316016   ⟹   XP_054171991
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
RefSeq Acc Id: XM_054316017   ⟹   XP_054171992
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
RefSeq Acc Id: XM_054316018   ⟹   XP_054171993
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
RefSeq Acc Id: XM_054316019   ⟹   XP_054171994
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01771,005,476 - 71,013,930 (+)NCBI
RefSeq Acc Id: XM_054316020   ⟹   XP_054171995
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001257351 (Get FASTA)   NCBI Sequence Viewer  
  NP_001278551 (Get FASTA)   NCBI Sequence Viewer  
  NP_001278552 (Get FASTA)   NCBI Sequence Viewer  
  NP_001278553 (Get FASTA)   NCBI Sequence Viewer  
  NP_001278554 (Get FASTA)   NCBI Sequence Viewer  
  NP_061128 (Get FASTA)   NCBI Sequence Viewer  
  NP_733937 (Get FASTA)   NCBI Sequence Viewer  
  NP_733938 (Get FASTA)   NCBI Sequence Viewer  
  XP_005257394 (Get FASTA)   NCBI Sequence Viewer  
  XP_006721949 (Get FASTA)   NCBI Sequence Viewer  
  XP_006721950 (Get FASTA)   NCBI Sequence Viewer  
  XP_011523083 (Get FASTA)   NCBI Sequence Viewer  
  XP_016880098 (Get FASTA)   NCBI Sequence Viewer  
  XP_016880099 (Get FASTA)   NCBI Sequence Viewer  
  XP_047291906 (Get FASTA)   NCBI Sequence Viewer  
  XP_047291907 (Get FASTA)   NCBI Sequence Viewer  
  XP_047291908 (Get FASTA)   NCBI Sequence Viewer  
  XP_047291909 (Get FASTA)   NCBI Sequence Viewer  
  XP_047291910 (Get FASTA)   NCBI Sequence Viewer  
  XP_047291911 (Get FASTA)   NCBI Sequence Viewer  
  XP_047291912 (Get FASTA)   NCBI Sequence Viewer  
  XP_047291913 (Get FASTA)   NCBI Sequence Viewer  
  XP_047291914 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171981 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171982 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171983 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171984 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171985 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171986 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171987 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171988 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171989 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171990 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171991 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171992 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171993 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171994 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171995 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF73238 (Get FASTA)   NCBI Sequence Viewer  
  AAF73239 (Get FASTA)   NCBI Sequence Viewer  
  AAF73240 (Get FASTA)   NCBI Sequence Viewer  
  AAF73244 (Get FASTA)   NCBI Sequence Viewer  
  AAG09401 (Get FASTA)   NCBI Sequence Viewer  
  AAH33038 (Get FASTA)   NCBI Sequence Viewer  
  BAF83488 (Get FASTA)   NCBI Sequence Viewer  
  EAW89090 (Get FASTA)   NCBI Sequence Viewer  
  EAW89091 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000283936
  ENSP00000283936.1
  ENSP00000376438
  ENSP00000376438.1
  ENSP00000376439
  ENSP00000376439.1
  ENSP00000465163.1
  ENSP00000465646.1
  ENSP00000465967.1
  ENSP00000466132.1
  ENSP00000479817
  ENSP00000479817.1
GenBank Protein Q9NPI9 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_733937   ⟸   NM_170741
- Peptide Label: isoform b
- UniProtKB: Q9NPI9 (UniProtKB/Swiss-Prot),   A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_061128   ⟸   NM_018658
- Peptide Label: isoform b
- UniProtKB: Q9NPI9 (UniProtKB/Swiss-Prot),   A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_733938   ⟸   NM_170742
- Peptide Label: isoform b
- UniProtKB: Q9NPI9 (UniProtKB/Swiss-Prot),   A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257351   ⟸   NM_001270422
- Peptide Label: isoform b
- UniProtKB: Q9NPI9 (UniProtKB/Swiss-Prot),   A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005257394   ⟸   XM_005257337
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006721949   ⟸   XM_006721886
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006721950   ⟸   XM_006721887
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278551   ⟸   NM_001291622
- Peptide Label: isoform b
- UniProtKB: Q9NPI9 (UniProtKB/Swiss-Prot),   A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278554   ⟸   NM_001291625
- Peptide Label: isoform b
- UniProtKB: Q9NPI9 (UniProtKB/Swiss-Prot),   A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278553   ⟸   NM_001291624
- Peptide Label: isoform b
- UniProtKB: Q9NPI9 (UniProtKB/Swiss-Prot),   A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278552   ⟸   NM_001291623
- Peptide Label: isoform b
- UniProtKB: Q9NPI9 (UniProtKB/Swiss-Prot),   A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011523083   ⟸   XM_011524781
- Peptide Label: isoform X2
- UniProtKB: Q9NPI9 (UniProtKB/Swiss-Prot),   A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016880098   ⟸   XM_017024609
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016880099   ⟸   XM_017024610
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000465295   ⟸   ENST00000585558
RefSeq Acc Id: ENSP00000283936   ⟸   ENST00000283936
RefSeq Acc Id: ENSP00000467568   ⟸   ENST00000586462
RefSeq Acc Id: ENSP00000465163   ⟸   ENST00000587892
RefSeq Acc Id: ENSP00000466132   ⟸   ENST00000587698
RefSeq Acc Id: ENSP00000465967   ⟸   ENST00000589377
RefSeq Acc Id: ENSP00000479817   ⟸   ENST00000615244
RefSeq Acc Id: ENSP00000376438   ⟸   ENST00000392670
RefSeq Acc Id: ENSP00000376439   ⟸   ENST00000392671
RefSeq Acc Id: ENSP00000465646   ⟸   ENST00000591891
RefSeq Acc Id: XP_047291909   ⟸   XM_047435953
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047291908   ⟸   XM_047435952
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047291906   ⟸   XM_047435950
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047291911   ⟸   XM_047435955
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047291907   ⟸   XM_047435951
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047291910   ⟸   XM_047435954
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047291912   ⟸   XM_047435956
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047291913   ⟸   XM_047435957
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047291914   ⟸   XM_047435958
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054171983   ⟸   XM_054316008
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054171988   ⟸   XM_054316013
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054171986   ⟸   XM_054316011
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054171981   ⟸   XM_054316006
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054171990   ⟸   XM_054316015
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054171982   ⟸   XM_054316007
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054171984   ⟸   XM_054316009
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054171989   ⟸   XM_054316014
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054171985   ⟸   XM_054316010
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054171987   ⟸   XM_054316012
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054171991   ⟸   XM_054316016
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054171995   ⟸   XM_054316020
- Peptide Label: isoform X2
- UniProtKB: Q9NPI9 (UniProtKB/Swiss-Prot),   A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054171992   ⟸   XM_054316017
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054171993   ⟸   XM_054316018
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054171994   ⟸   XM_054316019
- Peptide Label: isoform X1
- UniProtKB: A8K434 (UniProtKB/TrEMBL),   Q8N538 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9NPI9-F1-model_v2 AlphaFold Q9NPI9 1-418 view protein structure

Promoters
RGD ID:6794239
Promoter ID:HG_KWN:26979
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:UC002JIQ.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361765,634,936 - 65,635,436 (+)MPROMDB
RGD ID:7236155
Promoter ID:EPDNEW_H23823
Type:initiation region
Name:KCNJ16_1
Description:potassium voltage-gated channel subfamily J member 16
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381770,075,325 - 70,075,385EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6262 AgrOrtholog
COSMIC KCNJ16 COSMIC
Ensembl Genes ENSG00000153822 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000283936 ENTREZGENE
  ENST00000283936.5 UniProtKB/Swiss-Prot
  ENST00000392670 ENTREZGENE
  ENST00000392670.5 UniProtKB/Swiss-Prot
  ENST00000392671 ENTREZGENE
  ENST00000392671.6 UniProtKB/Swiss-Prot
  ENST00000587698.5 UniProtKB/TrEMBL
  ENST00000587892.1 UniProtKB/TrEMBL
  ENST00000589377.1 UniProtKB/Swiss-Prot
  ENST00000591891.5 UniProtKB/TrEMBL
  ENST00000615244 ENTREZGENE
  ENST00000615244.4 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.1400 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000153822 GTEx
HGNC ID HGNC:6262 ENTREZGENE
Human Proteome Map KCNJ16 Human Proteome Map
InterPro Ig_E-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRK_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir_cyto UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kir_TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:3773 UniProtKB/Swiss-Prot
NCBI Gene 3773 ENTREZGENE
OMIM 605722 OMIM
PANTHER PTHR11767 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11767:SF24 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IRK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRK_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA30047 PharmGKB
PIRSF GIRK_kir UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS KIR5CHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KIRCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF81296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A8K434 ENTREZGENE, UniProtKB/TrEMBL
  K7EKJ4_HUMAN UniProtKB/TrEMBL
  K7ELL5_HUMAN UniProtKB/TrEMBL
  KCJ16_HUMAN UniProtKB/Swiss-Prot
  Q8N538 ENTREZGENE, UniProtKB/TrEMBL
  Q9NPI9 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-07-23 KCNJ16  potassium inwardly rectifying channel subfamily J member 16  KCNJ16  potassium voltage-gated channel subfamily J member 16  Symbol and/or name change 5135510 APPROVED
2016-02-10 KCNJ16  potassium voltage-gated channel subfamily J member 16    potassium channel, inwardly rectifying subfamily J, member 16  Symbol and/or name change 5135510 APPROVED
2015-01-20 KCNJ16  potassium channel, inwardly rectifying subfamily J, member 16    potassium inwardly-rectifying channel, subfamily J, member 16  Symbol and/or name change 5135510 APPROVED