GPR32 (G protein-coupled receptor 32)

Gene: GPR32 (G protein-coupled receptor 32) Homo sapiens

Analyze

Symbol:

GPR32

Name:

G protein-coupled receptor 32

RGD ID:

1343074

HGNC Page

HGNC:4487

Description:

Predicted to enable N-formyl peptide receptor activity and complement receptor activity. Predicted to be involved in several processes, including complement receptor mediated signaling pathway; phospholipase C-activating G protein-coupled receptor signaling pathway; and positive regulation of cytosolic calcium ion concentration. Predicted to be located in membrane. Predicted to be active in plasma membrane.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

DRV1; probable G-protein coupled receptor 32; resolvin D1 receptor; RVDR1

RGD Orthologs

Alliance Genes

More Info

more info ...

Related Pseudogenes:

GPR32P1

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	50,770,464 - 50,771,732 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	50,770,464 - 50,771,732 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	51,273,721 - 51,274,989 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	55,965,670 - 55,966,740 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	55,965,669 - 55,966,740	NCBI
Celera	19	48,324,797 - 48,325,867 (+)	NCBI		Celera
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	47,608,695 - 47,609,963 (+)	NCBI		HuRef
CHM1_1	19	51,275,460 - 51,276,728 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	53,859,268 - 53,860,536 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (EXP)

genetic disease (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (EXP)

3-isobutyl-1-methyl-7H-xanthine (EXP)

benzo[a]pyrene (EXP)

benzo[e]pyrene (EXP)

bisphenol A (EXP)

butanal (EXP)

cadmium atom (EXP)

cadmium dichloride (EXP)

carmustine (EXP)

dexamethasone (EXP)

hydroquinone O-beta-D-glucopyranoside (EXP)

indometacin (EXP)

kojic acid (EXP)

methapyrilene (EXP)

paracetamol (EXP)

valproic acid (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

complement receptor mediated signaling pathway (IBA,IEA)

G protein-coupled receptor signaling pathway (IEA,TAS)

inflammatory response (IBA,IEA)

phospholipase C-activating G protein-coupled receptor signaling pathway (IBA,IEA)

positive regulation of cytosolic calcium ion concentration (IBA,IEA)

Cellular Component

membrane (IEA)

plasma membrane (IBA,IEA,TAS)

Molecular Function

complement receptor activity (IBA,IEA)

G protein-coupled receptor activity (IEA,TAS)

N-formyl peptide receptor activity (IBA,IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	GOAs Human GO annotations	GOA_HUMAN data from the GO Consortium
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:9653656	PMID:12477932	PMID:15489334	PMID:20080636	PMID:21873635	PMID:22542696	PMID:24120851	PMID:25030943	PMID:25320283	PMID:26339162	PMID:29083412	PMID:34339312
PMID:34699386

Genomics

Comparative Map Data

GPR32
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	50,770,464 - 50,771,732 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	50,770,464 - 50,771,732 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	51,273,721 - 51,274,989 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	55,965,670 - 55,966,740 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	55,965,669 - 55,966,740	NCBI
Celera	19	48,324,797 - 48,325,867 (+)	NCBI		Celera
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	47,608,695 - 47,609,963 (+)	NCBI		HuRef
CHM1_1	19	51,275,460 - 51,276,728 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	53,859,268 - 53,860,536 (+)	NCBI		T2T-CHM13v2.0

Gpr32
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	103,893,405 - 103,894,667 (-)	NCBI		GRCr8
mRatBN7.2	1	94,756,863 - 94,757,895 (-)	NCBI	mRatBN7.2	mRatBN7.2
Rnor_6.0	1	100,246,794 - 100,247,826 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Celera	1	89,023,437 - 89,024,469 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

Gpr32
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955559	500,852 - 501,880 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOC100980025
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	56,825,685 - 56,828,201 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	58,746,499 - 58,749,010 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	47,722,804 - 47,724,231 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	56,621,912 - 56,623,018 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

GPR32
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	55,509,963 - 55,522,400 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	55,519,932 - 55,522,402 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	51,419,016 - 51,420,945 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GPR32
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	43,814,864 - 43,816,274 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666073	23,831,616 - 23,832,935 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in GPR32
23 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 19q13.33-13.43(chr19:50191219-58535818)x3	copy number gain	See cases [RCV000050883]	Chr19:50191219..58535818 [GRCh38] Chr19:50694476..59047185 [GRCh37] Chr19:55386288..63738997 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:49907832-58557889)x3	copy number gain	See cases [RCV000052925]	Chr19:49907832..58557889 [GRCh38] Chr19:50411089..59069256 [GRCh37] Chr19:55102901..63761068 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47908540-58539965)x3	copy number gain	See cases [RCV000052914]	Chr19:47908540..58539965 [GRCh38] Chr19:48411797..59051332 [GRCh37] Chr19:53103609..63743144 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47929575-58572206)x3	copy number gain	See cases [RCV000052915]	Chr19:47929575..58572206 [GRCh38] Chr19:48432832..59083573 [GRCh37] Chr19:53124644..63775385 [NCBI36] Chr19:19q13.33-13.43	pathogenic
NM_001506.2(GPR32):c.92C>T (p.Ser31Phe)	single nucleotide variant	Malignant melanoma [RCV000072270]	Chr19:50770692 [GRCh38] Chr19:51273949 [GRCh37] Chr19:55965761 [NCBI36] Chr19:19q13.33	not provided
GRCh38/hg38 19q13.33-13.43(chr19:50152520-58581203)x3	copy number gain	See cases [RCV000135843]	Chr19:50152520..58581203 [GRCh38] Chr19:50655777..59092570 [GRCh37] Chr19:55347589..63784382 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh37/hg19 19q13.33-13.43(chr19:50489390-59095359)x3	copy number gain	See cases [RCV000445925]	Chr19:50489390..59095359 [GRCh37] Chr19:19q13.33-13.43	pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3	copy number gain	See cases [RCV000511289]	Chr19:260912..58956888 [GRCh37] Chr19:19p13.3-q13.43	pathogenic\|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)	copy number gain	See cases [RCV000512296]	Chr19:260912..58956888 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
NM_001506.2(GPR32):c.386A>T (p.Asn129Ile)	single nucleotide variant	Inborn genetic diseases [RCV003251734]	Chr19:50770986 [GRCh38] Chr19:51274243 [GRCh37] Chr19:19q13.33	likely benign
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3	copy number gain	not provided [RCV000752444]	Chr19:260912..59097160 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3	copy number gain	not provided [RCV000752439]	Chr19:68029..59110290 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
GRCh37/hg19 19q13.33(chr19:51262374-51275044)x1	copy number loss	not provided [RCV000740210]	Chr19:51262374..51275044 [GRCh37] Chr19:19q13.33	benign
GRCh37/hg19 19q13.33(chr19:51263296-51275044)x1	copy number loss	not provided [RCV000740211]	Chr19:51263296..51275044 [GRCh37] Chr19:19q13.33	benign
GRCh37/hg19 19q13.33-13.43(chr19:50740074-59097160)x3	copy number gain	not provided [RCV000740208]	Chr19:50740074..59097160 [GRCh37] Chr19:19q13.33-13.43	pathogenic
NM_001506.2(GPR32):c.5A>T (p.Asn2Ile)	single nucleotide variant	Inborn genetic diseases [RCV003267850]	Chr19:50770605 [GRCh38] Chr19:51273862 [GRCh37] Chr19:19q13.33	uncertain significance
GRCh37/hg19 19q13.33(chr19:49600909-51366070)x3	copy number gain	not provided [RCV000847250]	Chr19:49600909..51366070 [GRCh37] Chr19:19q13.33	uncertain significance
GRCh37/hg19 19q13.31-13.42(chr19:44738088-53621561)x3	copy number gain	not provided [RCV001007050]	Chr19:44738088..53621561 [GRCh37] Chr19:19q13.31-13.42	pathogenic
GRCh37/hg19 19q13.32-13.42(chr19:47939842-54626871)	copy number gain	not provided [RCV001249294]	Chr19:47939842..54626871 [GRCh37] Chr19:19q13.32-13.42	not provided
NM_001506.2(GPR32):c.503T>C (p.Leu168Pro)	single nucleotide variant	Inborn genetic diseases [RCV003293020]	Chr19:50771103 [GRCh38] Chr19:51274360 [GRCh37] Chr19:19q13.33	uncertain significance
GRCh37/hg19 19q13.33-13.41(chr19:50469730-51916485)x3	copy number gain	not provided [RCV001007055]	Chr19:50469730..51916485 [GRCh37] Chr19:19q13.33-13.41	uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:48463931-57095254)x3	copy number gain	not provided [RCV001259944]	Chr19:48463931..57095254 [GRCh37] Chr19:19q13.33-13.43	pathogenic
GRCh37/hg19 19q13.33-13.41(chr19:49911081-53127438)	copy number gain	not specified [RCV002052689]	Chr19:49911081..53127438 [GRCh37] Chr19:19q13.33-13.41	likely pathogenic
NC_000019.9:g.(?_50887648)_(51364623_?)dup	duplication	Colorectal cancer, susceptibility to, 10 [RCV001916525]	Chr19:50887648..51364623 [GRCh37] Chr19:19q13.33	uncertain significance
GRCh37/hg19 19q13.33(chr19:50883114-51304591)x3	copy number gain	not provided [RCV002474601]	Chr19:50883114..51304591 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.923A>G (p.Asn308Ser)	single nucleotide variant	Inborn genetic diseases [RCV002840332]	Chr19:50771523 [GRCh38] Chr19:51274780 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.128G>C (p.Arg43Pro)	single nucleotide variant	Inborn genetic diseases [RCV002991325]	Chr19:50770728 [GRCh38] Chr19:51273985 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.926G>A (p.Ser309Asn)	single nucleotide variant	Inborn genetic diseases [RCV002689013]	Chr19:50771526 [GRCh38] Chr19:51274783 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.847C>G (p.Arg283Gly)	single nucleotide variant	Inborn genetic diseases [RCV002794445]	Chr19:50771447 [GRCh38] Chr19:51274704 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.49G>A (p.Gly17Arg)	single nucleotide variant	Inborn genetic diseases [RCV002777749]	Chr19:50770649 [GRCh38] Chr19:51273906 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.653T>C (p.Ile218Thr)	single nucleotide variant	Inborn genetic diseases [RCV002865114]	Chr19:50771253 [GRCh38] Chr19:51274510 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.928A>T (p.Ser310Cys)	single nucleotide variant	Inborn genetic diseases [RCV002998228]	Chr19:50771528 [GRCh38] Chr19:51274785 [GRCh37] Chr19:19q13.33	likely benign
NM_001506.2(GPR32):c.988T>C (p.Ser330Pro)	single nucleotide variant	Inborn genetic diseases [RCV002955387]	Chr19:50771588 [GRCh38] Chr19:51274845 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.194T>C (p.Leu65Pro)	single nucleotide variant	Inborn genetic diseases [RCV002986569]	Chr19:50770794 [GRCh38] Chr19:51274051 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.199A>G (p.Met67Val)	single nucleotide variant	Inborn genetic diseases [RCV002986570]	Chr19:50770799 [GRCh38] Chr19:51274056 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.493G>A (p.Val165Met)	single nucleotide variant	Inborn genetic diseases [RCV002832009]	Chr19:50771093 [GRCh38] Chr19:51274350 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.403A>G (p.Ile135Val)	single nucleotide variant	Inborn genetic diseases [RCV003209401]	Chr19:50771003 [GRCh38] Chr19:51274260 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.89A>G (p.Asn30Ser)	single nucleotide variant	Inborn genetic diseases [RCV003220576]	Chr19:50770689 [GRCh38] Chr19:51273946 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.520T>G (p.Ser174Ala)	single nucleotide variant	Inborn genetic diseases [RCV003181088]	Chr19:50771120 [GRCh38] Chr19:51274377 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.446C>T (p.Ala149Val)	single nucleotide variant	Inborn genetic diseases [RCV003200893]	Chr19:50771046 [GRCh38] Chr19:51274303 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.202A>G (p.Thr68Ala)	single nucleotide variant	Inborn genetic diseases [RCV003193670]	Chr19:50770802 [GRCh38] Chr19:51274059 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.68G>C (p.Arg23Pro)	single nucleotide variant	Inborn genetic diseases [RCV003203087]	Chr19:50770668 [GRCh38] Chr19:51273925 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.529C>G (p.Leu177Val)	single nucleotide variant	Inborn genetic diseases [RCV003353280]	Chr19:50771129 [GRCh38] Chr19:51274386 [GRCh37] Chr19:19q13.33	uncertain significance
NM_001506.2(GPR32):c.538C>T (p.Arg180Trp)	single nucleotide variant	Inborn genetic diseases [RCV003351444]	Chr19:50771138 [GRCh38] Chr19:51274395 [GRCh37] Chr19:19q13.33	uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:49625130-57647352)x3	copy number gain	not provided [RCV003485200]	Chr19:49625130..57647352 [GRCh37] Chr19:19q13.33-13.43	likely pathogenic
GRCh37/hg19 19q13.33-13.41(chr19:48905537-51614930)x3	copy number gain	not specified [RCV003986127]	Chr19:48905537..51614930 [GRCh37] Chr19:19q13.33-13.41	likely pathogenic

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	217
Count of miRNA genes:	214
Interacting mature miRNAs:	217
Transcripts:	ENST00000270590
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region

GPR32_2034

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	19	51,274,202 - 51,275,091	UniSTS	GRCh37
Build 36	19	55,966,014 - 55,966,903	RGD	NCBI36
Celera	19	48,325,141 - 48,326,030	RGD
HuRef	19	47,609,176 - 47,610,065	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

adipose tissue

appendage

entire extraembryonic component

High

Medium

Low

Below cutoff

229

258

138

213

594

203

708

545

186

346

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001506	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC010325	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF045764	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC067453	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC067454	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC095544	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471135	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068259	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JQ308171	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000270590 ⟹ ENSP00000270590

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	50,770,464 - 50,771,732 (+)	Ensembl

RefSeq Acc Id:

NM_001506 ⟹ NP_001497

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	50,770,464 - 50,771,732 (+)	NCBI
GRCh37	19	51,273,721 - 51,274,989 (+)	NCBI
Build 36	19	55,965,670 - 55,966,740 (+)	NCBI Archive
Celera	19	48,324,797 - 48,325,867 (+)	RGD
HuRef	19	47,608,695 - 47,609,963 (+)	NCBI
CHM1_1	19	51,275,460 - 51,276,728 (+)	NCBI
T2T-CHM13v2.0	19	53,859,268 - 53,860,536 (+)	NCBI

Sequence:

show sequence

TCTTGAGCCTAGGAGGTGGAGGCTGCAGTGATCTGTGATTGTACCTTTGCACTCCAGCCTGGGT
GACAGAGCATGACGCTGTCTCTAAAAGAATAATAATAATAAGCATTCCATAAAAATTATGGAAT
GGAGAAATCATGAATGGGGTCTCGGAGGGGACCAGAGGCTGCAGTGACAGGCAACCTGGGGTCC
TGACACGTGATCGCTCTTGTTCCAGGAAGATGAACTCTTCCGGATGCCTGTCTGAGGAGGTGGG
GTCCCTCCGCCCACTGACTGTGGTTATCCTGTCTGCGTCCATTGTCGTCGGAGTGCTGGGCAAT
GGGCTGGTGCTGTGGATGACTGTCTTCCGTATGGCACGCACGGTCTCCACCGTCTGCTTCTTCC
ACCTGGCCCTTGCCGATTTCATGCTCTCACTGTCTCTGCCCATTGCCATGTACTATATTGTCTC
CAGGCAGTGGCTCCTCGGAGAGTGGGCCTGCAAACTCTACATCACCTTTGTGTTCCTCAGCTAC
TTTGCCAGTAACTGCCTCCTTGTCTTCATCTCTGTGGACCGTTGCATCTCTGTCCTCTACCCCG
TCTGGGCCCTGAACCACCGCACTGTGCAGCGGGCGAGCTGGCTGGCCTTTGGGGTGTGGCTCCT
GGCCGCCGCCTTGTGCTCTGCGCACCTGAAATTCCGGACAACCAGAAAATGGAATGGCTGTACG
CACTGCTACTTGGCGTTCAACTCTGACAATGAGACTGCCCAGATTTGGATTGAAGGGGTCGTGG
AGGGACACATTATAGGGACCATTGGCCACTTCCTGCTGGGCTTCCTGGGGCCCTTAGCAATCAT
AGGCACCTGCGCCCACCTCATCCGGGCCAAGCTCTTGCGGGAGGGCTGGGTCCATGCCAACCGG
CCCAAGAGGCTGCTGCTGGTGCTGGTGAGCGCTTTCTTTATCTTCTGGTCCCCGTTTAACGTGG
TGCTGTTGGTCCATCTGTGGCGACGGGTGATGCTCAAGGAAATCTACCACCCCCGGATGCTGCT
CATCCTCCAGGCTAGCTTTGCCTTGGGCTGTGTCAACAGCAGCCTCAACCCCTTCCTCTACGTC
TTCGTTGGCAGAGATTTCCAAGAAAAGTTTTTCCAGTCTTTGACTTCTGCCCTGGCGAGGGCGT
TTGGAGAGGAGGAGTTTCTGTCATCCTGTCCCCGTGGCAACGCCCCCCGGGAATGATGGAAGAC
TTCAGCTGGAAGCTGGAAGCCGTCCTTCTTAGTTTGCTTGTGGCCTCTTACCT

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Protein Sequences


Protein RefSeqs	NP_001497	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC39801	(Get FASTA)	NCBI Sequence Viewer
	AAH67453	(Get FASTA)	NCBI Sequence Viewer
	AAH67454	(Get FASTA)	NCBI Sequence Viewer
	AAH95544	(Get FASTA)	NCBI Sequence Viewer
	AFF59481	(Get FASTA)	NCBI Sequence Viewer
	EAW71898	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000270590
	ENSP00000270590.3
GenBank Protein	O75388	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001497 ⟸ NM_001506

- UniProtKB:

Q502U7 (UniProtKB/Swiss-Prot), Q6NWS5 (UniProtKB/Swiss-Prot), O75388 (UniProtKB/Swiss-Prot), H9NIL6 (UniProtKB/TrEMBL)

- Sequence:

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MNGVSEGTRGCSDRQPGVLTRDRSCSRKMNSSGCLSEEVGSLRPLTVVILSASIVVGVLGNGLV
LWMTVFRMARTVSTVCFFHLALADFMLSLSLPIAMYYIVSRQWLLGEWACKLYITFVFLSYFAS
NCLLVFISVDRCISVLYPVWALNHRTVQRASWLAFGVWLLAAALCSAHLKFRTTRKWNGCTHCY
LAFNSDNETAQIWIEGVVEGHIIGTIGHFLLGFLGPLAIIGTCAHLIRAKLLREGWVHANRPKR
LLLVLVSAFFIFWSPFNVVLLVHLWRRVMLKEIYHPRMLLILQASFALGCVNSSLNPFLYVFVG
RDFQEKFFQSLTSALARAFGEEEFLSSCPRGNAPRE

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RefSeq Acc Id:

ENSP00000270590 ⟸ ENST00000270590

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O75388-F1-model_v2	AlphaFold	O75388	1-356	view protein structure

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:4487	AgrOrtholog
COSMIC	GPR32	COSMIC
Ensembl Genes	ENSG00000142511	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000270590	ENTREZGENE
	ENST00000270590.4	UniProtKB/Swiss-Prot
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx	ENSG00000142511	GTEx
HGNC ID	HGNC:4487	ENTREZGENE
Human Proteome Map	GPR32	Human Proteome Map
InterPro	Formyl_rcpt-rel	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	hsa:2854	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	2854	ENTREZGENE
OMIM	603195	OMIM
PANTHER	G-PROTEIN COUPLED RECEPTOR 32-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR24225	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA28875	PharmGKB
PRINTS	FMETLEUPHER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCRRHODOPSN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	GPR32_HUMAN	UniProtKB/Swiss-Prot
	H9NIL6	ENTREZGENE, UniProtKB/TrEMBL
	O75388	ENTREZGENE
	Q502U7	ENTREZGENE
	Q6NWS5	ENTREZGENE
UniProt Secondary	Q502U7	UniProtKB/Swiss-Prot
	Q6NWS5	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD