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Gene: PIR (pirin) Homo sapiens
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Symbol: PIR
Name: pirin
Description: Exhibits metal ion binding activity; quercetin 2,3-dioxygenase activity; and transcription coregulator activity. Involved in monocyte differentiation. Localizes to the cytosol and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: pirin (iron-binding nuclear protein); probable quercetin 2,3-dioxygenase PIR; probable quercetinase
Orthologs:
Mus musculus (house mouse) : Pir (pirin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pir (pirin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pir (pirin)
Pan paniscus (bonobo/pygmy chimpanzee) : PIR (pirin)
Canis lupus familiaris (dog) : PIR (pirin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pir (pirin)
Sus scrofa (pig) : PIR (pirin)
Chlorocebus sabaeus (African green monkey) : PIR (pirin)
Heterocephalus glaber (naked mole-rat) : Pir (pirin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 EnsemblX15,384,799 - 15,493,564 (-)Ensembl
GRCh38X15,384,799 - 15,493,588 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X15,402,921 - 15,511,711 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X15,312,842 - 15,421,385 (-)NCBINCBI36hg18NCBI36
Build 34X15,162,582 - 15,271,113NCBI
CeleraX19,518,436 - 19,626,837 (-)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX13,159,639 - 13,268,835 (-)NCBIHuRef
CHM1_1X15,433,843 - 15,542,647 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PIR
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1342511
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-31
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.