CXCL17 (C-X-C motif chemokine ligand 17) - Rat Genome Database

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Gene: CXCL17 (C-X-C motif chemokine ligand 17) Canis lupus familiaris
Analyze
Symbol: CXCL17
Name: C-X-C motif chemokine ligand 17
RGD ID: 13421151
Description: INVOLVED IN macrophage chemotaxis (inferred); negative regulation of inflammatory response (inferred); positive regulation of ERK1 and ERK2 cascade (inferred); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); schizophrenia (ortholog); FOUND IN extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C-X-C motif chemokine 17; chemokine (C-X-C motif) ligand 17
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11111,969,808 - 111,986,767 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1111,970,131 - 111,986,433 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1111,394,613 - 111,411,457 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01112,580,880 - 112,597,756 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1112,581,089 - 112,597,759 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11112,135,121 - 112,152,091 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01111,770,648 - 111,787,320 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01112,697,479 - 112,714,340 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CXCL17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11111,969,808 - 111,986,767 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1111,970,131 - 111,986,433 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1111,394,613 - 111,411,457 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01112,580,880 - 112,597,756 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1112,581,089 - 112,597,759 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11112,135,121 - 112,152,091 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01111,770,648 - 111,787,320 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01112,697,479 - 112,714,340 (+)NCBIUU_Cfam_GSD_1.0
CXCL17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381942,428,278 - 42,442,946 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1942,428,278 - 42,442,946 (-)EnsemblGRCh38hg38GRCh38
GRCh371942,932,430 - 42,947,098 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,624,535 - 47,638,976 (-)NCBINCBI36Build 36hg18NCBI36
Celera1939,733,484 - 39,747,927 (-)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1939,362,820 - 39,377,263 (-)NCBIHuRef
CHM1_11942,934,348 - 42,948,806 (-)NCBICHM1_1
T2T-CHM13v2.01945,247,666 - 45,262,340 (-)NCBIT2T-CHM13v2.0
Cxcl17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39725,099,478 - 25,112,311 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl725,099,478 - 25,112,311 (-)EnsemblGRCm39 Ensembl
GRCm38725,400,053 - 25,412,886 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl725,400,053 - 25,412,886 (-)EnsemblGRCm38mm10GRCm38
MGSCv37726,185,072 - 26,197,905 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36725,108,813 - 25,121,646 (-)NCBIMGSCv36mm8
Celera720,015,378 - 20,028,341 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.8NCBI
Cxcl17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8190,112,561 - 90,124,648 (-)NCBIGRCr8
mRatBN7.2180,984,751 - 80,996,842 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl180,984,964 - 80,996,726 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx186,377,164 - 86,388,927 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0194,928,403 - 94,940,107 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0188,132,948 - 88,144,711 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0182,267,381 - 82,279,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,267,381 - 82,279,145 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,530,854 - 83,542,736 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,683,134 - 80,694,898 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1180,761,243 - 80,772,960 (-)NCBI
Celera175,426,585 - 75,438,349 (-)NCBICelera
Cytogenetic Map1q21NCBI
Cxcl17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955555495,445 - 509,788 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955555495,437 - 509,788 (+)NCBIChiLan1.0ChiLan1.0
CXCL17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22048,533,795 - 48,547,898 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11950,401,716 - 50,428,109 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01939,315,929 - 39,331,651 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11947,908,174 - 47,922,120 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1947,908,179 - 47,922,120 (-)Ensemblpanpan1.1panPan2
Cxcl17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934915,715,971 - 15,771,909 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936706113,586 - 119,374 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493670662,417 - 119,278 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100737180
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl650,051,061 - 50,063,295 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1650,037,606 - 50,063,561 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2645,966,736 - 45,974,149 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CXCL17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1636,631,508 - 36,651,508 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl636,631,565 - 36,649,986 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607314,877,911 - 14,894,600 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cxcl17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624907345,800 - 359,450 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624907345,786 - 359,450 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CXCL17
260 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 1
Medium 2 6
Low 1 5 1 2 8 3 1
Below cutoff 4 4 9 2 6 2 5 4 5 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000007753   ⟹   ENSCAFP00000007185
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1111,970,131 - 111,986,433 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845001151   ⟹   ENSCAFP00845000872
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1112,581,089 - 112,597,759 (+)Ensembl
RefSeq Acc Id: XM_022403494   ⟹   XP_022259202
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11111,969,835 - 111,986,767 (+)NCBI
Dog10K_Boxer_Tasha1111,394,613 - 111,411,457 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022403499   ⟹   XP_022259207
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11111,969,808 - 111,986,767 (+)NCBI
Dog10K_Boxer_Tasha1111,394,623 - 111,411,457 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038467984   ⟹   XP_038323912
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11112,135,361 - 112,152,091 (+)NCBI
RefSeq Acc Id: XM_038467985   ⟹   XP_038323913
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11112,135,121 - 112,152,091 (+)NCBI
RefSeq Acc Id: XM_038528720   ⟹   XP_038384648
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01112,697,479 - 112,714,340 (+)NCBI
RefSeq Acc Id: XM_038528721   ⟹   XP_038384649
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01112,697,489 - 112,714,340 (+)NCBI
RefSeq Acc Id: XM_038592997   ⟹   XP_038448925
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01111,770,648 - 111,787,320 (+)NCBI
RefSeq Acc Id: XM_038656810   ⟹   XP_038512738
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01112,580,880 - 112,597,756 (+)NCBI
RefSeq Acc Id: XM_038656811   ⟹   XP_038512739
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01112,580,890 - 112,597,756 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_022259207   ⟸   XM_022403499
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_022259202   ⟸   XM_022403494
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MAV2 (UniProtKB/TrEMBL),   A0A8I3MC88 (UniProtKB/TrEMBL),   A0A8C0ST64 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000007185   ⟸   ENSCAFT00000007753
RefSeq Acc Id: XP_038323913   ⟸   XM_038467985
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038323912   ⟸   XM_038467984
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038448925   ⟸   XM_038592997
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038512738   ⟸   XM_038656810
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MAV2 (UniProtKB/TrEMBL),   A0A8I3MC88 (UniProtKB/TrEMBL),   A0A8C0ST64 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038512739   ⟸   XM_038656811
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038384648   ⟸   XM_038528720
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MAV2 (UniProtKB/TrEMBL),   A0A8C0ST64 (UniProtKB/TrEMBL),   A0A8I3MC88 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038384649   ⟸   XM_038528721
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCAFP00845000872   ⟸   ENSCAFT00845001151


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000004810 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030004559 UniProtKB/TrEMBL
  ENSCAFG00030023044 UniProtKB/TrEMBL
  ENSCAFG00040016010 UniProtKB/TrEMBL
  ENSCAFG00845000701 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000007753.5 UniProtKB/TrEMBL
  ENSCAFT00030008375.1 UniProtKB/TrEMBL
  ENSCAFT00030042352.1 UniProtKB/TrEMBL
  ENSCAFT00040029495.1 UniProtKB/TrEMBL
  ENSCAFT00845001151 ENTREZGENE
  ENSCAFT00845001151.1 UniProtKB/TrEMBL
InterPro CXCL17 UniProtKB/TrEMBL
NCBI Gene CXCL17 ENTREZGENE
PANTHER C-X-C MOTIF CHEMOKINE 17 UniProtKB/TrEMBL
  PTHR37351 UniProtKB/TrEMBL
Pfam CXCL17 UniProtKB/TrEMBL
UniProt A0A8C0MAV2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0ST64 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MC88 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:49733 ENTREZGENE