Or2aj4 (olfactory receptor family 1 subfamily O member 4) - Rat Genome Database

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Pathways
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Gene: Or2aj4 (olfactory receptor family 1 subfamily O member 4) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or2aj4
Name: olfactory receptor family 1 subfamily O member 4
RGD ID: 1333622
Description: Predicted to enable G protein-coupled receptor activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1566; olfactory receptor gene Olr1566; olfactory receptor Olr1566; Olr1566; ratchr11-83598152-83599093_ORF
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81194,782,974 - 94,783,915 (+)NCBIGRCr8
mRatBN7.21181,278,605 - 81,279,546 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,271,250 - 81,279,959 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1190,016,035 - 90,016,974 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01182,677,229 - 82,678,168 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01181,730,519 - 81,731,458 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01185,189,277 - 85,190,223 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1185,189,277 - 85,190,223 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01188,243,230 - 88,244,176 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41183,540,231 - 83,541,172 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11183,598,151 - 83,599,093 (+)NCBI
Celera1180,112,943 - 80,113,884 (+)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.

Genomics

Variants

.
Variants in Or2aj4
7 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:133
Count of miRNA genes:108
Interacting mature miRNAs:112
Transcripts:ENSRNOT00000046865
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116944607082846715Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)117695713183051965Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

hemolymphoid system reproductive system respiratory system
High
Medium
Low
Below cutoff 2 3 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001000044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000046865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1181,271,250 - 81,279,959 (+)Ensembl
Rnor_6.0 Ensembl1185,189,277 - 85,190,223 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000109714   ⟹   ENSRNOP00000079774
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1181,271,250 - 81,279,959 (+)Ensembl
RefSeq Acc Id: NM_001000044   ⟹   NP_001000044
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,782,974 - 94,783,915 (+)NCBI
mRatBN7.21181,278,605 - 81,279,546 (+)NCBI
Rnor_6.01185,189,277 - 85,190,223 (+)NCBI
Rnor_5.01188,243,230 - 88,244,176 (+)NCBI
RGSC_v3.41183,540,231 - 83,541,172 (+)RGD
Celera1180,112,943 - 80,113,884 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000044 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000079774.1
  ENSRNOP00000095570
  ENSRNOP00000095570.1
Reference Protein Sequences
RefSeq Acc Id: NP_001000044   ⟸   NM_001000044
- UniProtKB: A0A8I6AN82 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000079774   ⟸   ENSRNOT00000109714
Protein Domains
G-protein coupled receptors family 1 profile

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-20695 BioCyc
Ensembl Genes ENSRNOG00000049950 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000046865 ENTREZGENE
  ENSRNOT00000046865.5 UniProtKB/TrEMBL
  ENSRNOT00000109714.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
NCBI Gene 287973 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  PTHR26453:SF214 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or2aj4 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000049950 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I6AN82 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or2aj4  olfactory receptor family 1 subfamily O member 4  Olr1566  olfactory receptor 1566  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1566  olfactory receptor 1566   Olr1566_predicted  olfactory receptor 1566 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1566_predicted  olfactory receptor 1566 (predicted)      Symbol and Name status set to approved 70820 APPROVED