Olr1675 (olfactory receptor 1675) - Rat Genome Database

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Pathways
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Gene: Olr1675 (olfactory receptor 1675) Rattus norvegicus
Analyze
Symbol: Olr1675
Name: olfactory receptor 1675
RGD ID: 1333465
Description: Predicted to enable G protein-coupled receptor activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane; INTERACTS WITH acrylamide; glyphosate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: olfactory receptor gene Olr1675; olfactory receptor Olr1670-like; olfactory receptor Olr1675
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr820297,130 - 298,068 (-)NCBIGRCr8
mRatBN7.220291,840 - 292,778 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl20291,088 - 295,953 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl20297,043 - 354,706 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx20294,349 - 295,287 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.020297,814 - 298,752 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.020293,552 - 294,490 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.020437,635 - 456,216 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl20437,638 - 529,024 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.020421,641 - 440,222 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.420212,579 - 213,517 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.120212,578 - 213,517 (-)NCBI
Celera201,155,124 - 1,156,062 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
acrylamide  (EXP)
glyphosate  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
plasma membrane  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline

Genomics

Variants

.
Variants in Olr1675
8 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:122
Count of miRNA genes:87
Interacting mature miRNAs:93
Transcripts:ENSRNOT00000047483
Prediction methods:Microtar
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system reproductive system
High
Medium
Low 1
Below cutoff 2 8

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001000894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000075114   ⟹   ENSRNOP00000065703
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl20297,043 - 354,706 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000106674   ⟹   ENSRNOP00000084366
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl20291,088 - 295,953 (-)Ensembl
RefSeq Acc Id: NM_001000894   ⟹   NP_001000894
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr820297,130 - 298,068 (-)NCBI
mRatBN7.220291,840 - 292,778 (-)NCBI
Rnor_6.020437,635 - 456,216 (-)NCBI
Rnor_5.020421,641 - 440,222 (-)NCBI
RGSC_v3.420212,579 - 213,517 (-)RGD
Celera201,155,124 - 1,156,062 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000894 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000065703.3
  ENSRNOP00000084366
  ENSRNOP00000084366.1
Reference Protein Sequences
RefSeq Acc Id: NP_001000894   ⟸   NM_001000894
- UniProtKB: A0A8I5ZZ32 (UniProtKB/TrEMBL),   M0R8A8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000084366   ⟸   ENSRNOT00000106674
RefSeq Acc Id: ENSRNOP00000065703   ⟸   ENSRNOT00000075114
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R8A8-F1-model_v2 AlphaFold M0R8A8 1-312 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-5087 BioCyc
Ensembl Genes ENSRNOG00000050389 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000063793 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000075114.3 UniProtKB/TrEMBL
  ENSRNOT00000106674 ENTREZGENE
  ENSRNOT00000106674.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:405196 UniProtKB/TrEMBL
NCBI Gene 405196 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Olr1675 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000050389 RatGTEx
  ENSRNOG00000063793 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I5ZZ32 ENTREZGENE, UniProtKB/TrEMBL
  M0R8A8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Olr1675  olfactory receptor 1675  LOC100365496  olfactory receptor Olr1670-like  Data merged from RGD:2318984 1643240 APPROVED
2010-05-05 LOC100365496  olfactory receptor Olr1670-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Olr1675  olfactory receptor 1675   Olr1675_predicted  olfactory receptor 1675 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1675_predicted  olfactory receptor 1675 (predicted)      Symbol and Name status set to approved 70820 APPROVED