Or9s18 (olfactory receptor family 9 subfamily S member 18) - Rat Genome Database

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Gene: Or9s18 (olfactory receptor family 9 subfamily S member 18) Rattus norvegicus
Analyze
Symbol: Or9s18
Name: olfactory receptor family 9 subfamily S member 18
RGD ID: 1333425
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR9H1P (olfactory receptor family 9 subfamily H member 1 pseudogene); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; bisphenol A; PCB138.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1652; olfactory receptor gene Olr1652; olfactory receptor Olr1652; Olr1652
RGD Orthologs
Human
Mouse
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81739,531 - 40,457 (+)NCBIGRCr8
mRatBN7.21733,740 - 34,666 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1731,666 - 37,373 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1753,734 - 54,660 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0171,596,303 - 1,597,229 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01751,153 - 52,079 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0172,704,197 - 2,705,123 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,704,197 - 2,705,123 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0174,938,057 - 4,938,983 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4175,504,665 - 5,505,591 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1175,504,664 - 5,505,591 (+)NCBI
Celera172,473,889 - 2,474,815 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or9s18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81739,531 - 40,457 (+)NCBIGRCr8
mRatBN7.21733,740 - 34,666 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1731,666 - 37,373 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1753,734 - 54,660 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0171,596,303 - 1,597,229 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01751,153 - 52,079 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0172,704,197 - 2,705,123 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,704,197 - 2,705,123 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0174,938,057 - 4,938,983 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4175,504,665 - 5,505,591 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1175,504,664 - 5,505,591 (+)NCBI
Celera172,473,889 - 2,474,815 (-)NCBICelera
Cytogenetic Map17p14NCBI
OR9H1P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381247,770,169 - 247,779,524 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1247,770,169 - 247,779,524 (+)EnsemblGRCh38hg38GRCh38
GRCh371247,933,471 - 247,942,826 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361246,004,735 - 246,005,858 (+)NCBINCBI36Build 36hg18NCBI36
Celera1221,230,743 - 221,231,666 (+)NCBICelera
Cytogenetic Map1q44NCBI
HuRef1218,326,715 - 218,327,638 (+)NCBIHuRef
CHM1_11249,210,520 - 249,211,443 (+)NCBICHM1_1
T2T-CHM13v2.01247,201,009 - 247,210,363 (+)NCBIT2T-CHM13v2.0
Or9s18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391365,300,040 - 65,300,966 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1365,298,054 - 65,303,966 (+)EnsemblGRCm39 Ensembl
GRCm381365,152,226 - 65,153,152 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1365,150,240 - 65,156,152 (+)EnsemblGRCm38mm10GRCm38
MGSCv371365,253,534 - 65,254,460 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361365,167,017 - 65,167,943 (+)NCBIMGSCv36mm8
Celera1366,792,981 - 66,793,907 (+)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1334.4NCBI

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:126
Count of miRNA genes:104
Interacting mature miRNAs:111
Transcripts:ENSRNOT00000024940
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122871563Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system exocrine system hemolymphoid system hepatobiliary system nervous system reproductive system respiratory system
High
Medium
Low
Below cutoff 2 1 1 1 5 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000024940   ⟹   ENSRNOP00000024940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl172,704,197 - 2,705,123 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000098502   ⟹   ENSRNOP00000092449
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1731,666 - 37,373 (+)Ensembl
RefSeq Acc Id: NM_001001122   ⟹   NP_001001122
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81739,531 - 40,457 (+)NCBI
mRatBN7.21733,740 - 34,666 (+)NCBI
Rnor_6.0172,704,197 - 2,705,123 (-)NCBI
Rnor_5.0174,938,057 - 4,938,983 (-)NCBI
RGSC_v3.4175,504,665 - 5,505,591 (+)RGD
Celera172,473,889 - 2,474,815 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001001122 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL84451 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000092449
  ENSRNOP00000092449.1
Reference Protein Sequences
RefSeq Acc Id: NP_001001122   ⟸   NM_001001122
- UniProtKB: D4ACV6 (UniProtKB/TrEMBL),   A6KQF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000024940   ⟸   ENSRNOT00000024940
RefSeq Acc Id: ENSRNOP00000092449   ⟸   ENSRNOT00000098502
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ACV6-F1-model_v2 AlphaFold D4ACV6 1-308 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333425 AgrOrtholog
BioCyc Gene G2FUF-10565 BioCyc
Ensembl Genes ENSRNOG00000018492 Ensembl
  ENSRNOG00000067756 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000098502 ENTREZGENE
  ENSRNOT00000098502.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:406035 UniProtKB/TrEMBL
NCBI Gene 406035 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or9s18 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018492 RatGTEx
  ENSRNOG00000067756 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6KQF7 ENTREZGENE, UniProtKB/TrEMBL
  D4ACV6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or9s18  olfactory receptor family 9 subfamily S member 18  Olr1652  olfactory receptor 1652  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1652  olfactory receptor 1652   Olr1652_predicted  olfactory receptor 1652 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1652_predicted  olfactory receptor 1652 (predicted)      Symbol and Name status set to approved 70820 APPROVED