Wdr83 (WD repeat domain containing 83) - Rat Genome Database
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Gene: Wdr83 (WD repeat domain containing 83) Mus musculus
Analyze
Symbol: Wdr83
Name: WD repeat domain containing 83
RGD ID: 1332476
MGI Page MGI
Description: Involved in several processes, including cytokine production; inflammatory response to wounding; and response to lipopolysaccharide. Localizes to cytoplasm and nucleus. Is expressed in embryo. Orthologous to human WDR83 (WD repeat domain 83); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; ethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1500041N16Rik; MAPK cascade scaffold protein; MAPK organizer 1; mitogen-activated protein kinase organizer 1; Mor; Morg1; WD repeat domain-containing protein 83
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39885,801,664 - 85,807,375 (-)NCBIGRCm39mm39
GRCm38885,075,035 - 85,080,746 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl885,075,035 - 85,081,306 (-)EnsemblGRCm38mm10GRCm38
MGSCv37887,598,934 - 87,604,645 (-)NCBIGRCm37mm9NCBIm37
MGSCv36887,965,140 - 87,970,851 (-)NCBImm8
Celera889,369,518 - 89,375,212 (-)NCBICelera
Cytogenetic Map8C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:15118098   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16751776   PMID:19726548   PMID:21267068  
PMID:21677750   PMID:22555025   PMID:22982595   PMID:24030251   PMID:25550320   PMID:28992060   PMID:29091030   PMID:29402223   PMID:30196744  


Genomics

Comparative Map Data
Wdr83
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39885,801,664 - 85,807,375 (-)NCBIGRCm39mm39
GRCm38885,075,035 - 85,080,746 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl885,075,035 - 85,081,306 (-)EnsemblGRCm38mm10GRCm38
MGSCv37887,598,934 - 87,604,645 (-)NCBIGRCm37mm9NCBIm37
MGSCv36887,965,140 - 87,970,851 (-)NCBImm8
Celera889,369,518 - 89,375,212 (-)NCBICelera
Cytogenetic Map8C3NCBI
WDR83
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1912,666,802 - 12,675,832 (+)EnsemblGRCh38hg38GRCh38
GRCh381912,666,807 - 12,675,832 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371912,777,618 - 12,786,646 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361912,638,628 - 12,647,646 (+)NCBINCBI36hg18NCBI36
Celera1912,667,332 - 12,676,360 (+)NCBI
Cytogenetic Map19p13.13NCBI
HuRef1912,350,706 - 12,359,681 (+)NCBIHuRef
CHM1_11912,778,123 - 12,787,151 (+)NCBICHM1_1
Wdr83
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01926,188,644 - 26,194,193 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1926,188,638 - 26,194,198 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01937,164,267 - 37,169,816 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41924,733,303 - 24,738,851 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11924,738,197 - 24,743,526 (+)NCBI
Celera1922,634,987 - 22,640,536 (+)NCBICelera
Cytogenetic Map19q11NCBI
Wdr83
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541531,774,017 - 31,778,737 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541531,774,017 - 31,778,737 (+)NCBIChiLan1.0ChiLan1.0
WDR83
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11912,976,952 - 12,983,221 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1912,976,952 - 12,983,221 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01912,231,876 - 12,237,997 (+)NCBIMhudiblu_PPA_v0panPan3
WDR83
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2049,439,387 - 49,443,661 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12049,439,387 - 49,443,661 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Wdr83
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366591,796,030 - 1,803,714 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR83
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl266,307,653 - 66,312,844 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1266,307,652 - 66,312,839 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2266,686,846 - 66,692,001 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WDR83
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1611,358,172 - 11,364,301 (+)NCBI
ChlSab1.1 Ensembl611,358,254 - 11,364,147 (+)Ensembl
Wdr83
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624901310,709 - 315,302 (+)NCBI

Position Markers
MARC_7999-8000:996688236:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381512,181,265 - 12,181,454UniSTSGRCm38
GRCm38885,081,241 - 85,081,999UniSTSGRCm38
MGSCv37887,605,140 - 87,605,898UniSTSGRCm37
MGSCv371512,111,020 - 12,111,209UniSTSGRCm37
Celera1511,960,642 - 11,960,831UniSTS
Celera889,375,707 - 89,376,465UniSTS
Cytogenetic Map15A1UniSTS
Cytogenetic Map15AUniSTS
Cytogenetic Map8C3UniSTS
UniSTS:225076  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38885,074,974 - 85,075,158UniSTSGRCm38
MGSCv37887,598,873 - 87,599,057UniSTSGRCm37
Celera889,369,457 - 89,369,641UniSTS
Cytogenetic Map8C3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined870305375104305495Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined870305375104305495Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871102903105103009Mouse
4141395Char2a_mP. chabaudi malaria resistance QTL 2a (mouse)Not determined7113678390202598Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71287817123895615Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871287817123895615Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined871396181105396393Mouse
1300920Pitm3_mprion incubation time 3 (mouse)Not determined873202495107202598Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)873400000126100000Mouse
1558890Lith18_mlithogenic gene 18 (mouse)Not determined875675517109675623Mouse
1357470Obq16_mobesity QTL 16 (mouse)Not determined875685348109685497Mouse
1301808Nhdlq1_mnon-HDL QTL 1 (mouse)Not determined875685348109685497Mouse
1301874Hdlq16_mHDL QTL 16 (mouse)Not determined875685348109685497Mouse
10412234Nhdlq14_mnon-HDL QTL 14 (mouse)Not determined875685348109685497Mouse
1301099Cbm2_mcerebellum weight 2 (mouse)Not determined878518613112518703Mouse
1301581Char2_mP. chabaudi malaria resistance QTL 2 (mouse)Not determined879082178113082403Mouse
12904012Cfq10_mconditioned fear QTL 10 (mouse)88006677589014359Mouse
10755530Wbc2_mwhite blood cell count 2 (mouse)881092664115092664Mouse
10755519Wbc1_mwhite blood cell count 1 (mouse)881619151115619151Mouse
1301766Desp1_mdespair 1 (mouse)Not determined884759576118759741Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1326
Count of miRNA genes:476
Interacting mature miRNAs:557
Transcripts:ENSMUST00000093357, ENSMUST00000131909, ENSMUST00000135463, ENSMUST00000136696, ENSMUST00000142201, ENSMUST00000145880, ENSMUST00000146900, ENSMUST00000149050, ENSMUST00000152186, ENSMUST00000152785
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000093357   ⟹   ENSMUSP00000091048
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,075,035 - 85,080,746 (-)Ensembl
RefSeq Acc Id: ENSMUST00000131909
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,075,035 - 85,080,632 (-)Ensembl
RefSeq Acc Id: ENSMUST00000135463
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,079,695 - 85,080,669 (-)Ensembl
RefSeq Acc Id: ENSMUST00000136696
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,075,035 - 85,080,703 (-)Ensembl
RefSeq Acc Id: ENSMUST00000142201   ⟹   ENSMUSP00000122737
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,075,037 - 85,076,107 (-)Ensembl
RefSeq Acc Id: ENSMUST00000145880
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,075,036 - 85,079,915 (-)Ensembl
RefSeq Acc Id: ENSMUST00000146900
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,075,038 - 85,076,291 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149050   ⟹   ENSMUSP00000121568
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,076,124 - 85,080,674 (-)Ensembl
RefSeq Acc Id: ENSMUST00000152186
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,075,052 - 85,081,306 (-)Ensembl
RefSeq Acc Id: ENSMUST00000152785   ⟹   ENSMUSP00000122127
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,075,828 - 85,080,673 (-)Ensembl
RefSeq Acc Id: NM_026399   ⟹   NP_080675
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39885,801,664 - 85,807,375 (-)NCBI
GRCm38885,075,035 - 85,080,746 (-)ENTREZGENE
MGSCv37887,598,934 - 87,604,645 (-)RGD
Celera889,369,518 - 89,375,212 (-)RGD
cM Map8 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_080675   ⟸   NM_026399
- UniProtKB: Q9DAJ4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000122127   ⟸   ENSMUST00000152785
RefSeq Acc Id: ENSMUSP00000091048   ⟸   ENSMUST00000093357
RefSeq Acc Id: ENSMUSP00000121568   ⟸   ENSMUST00000149050
RefSeq Acc Id: ENSMUSP00000122737   ⟸   ENSMUST00000142201
Protein Domains
WD_REPEATS_REGION

Promoters
RGD ID:8667745
Promoter ID:EPDNEW_M11904
Type:initiation region
Name:Wdr83_1
Description:Mus musculus WD repeat domain containing 83 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38885,080,706 - 85,080,766EPDNEW
RGD ID:6843897
Promoter ID:MM_KWN:55140
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000005281,   NM_026399,   OTTMUST00000074324,   OTTMUST00000074325,   OTTMUST00000074326,   OTTMUST00000074327,   OTTMUST00000074330,   OTTMUST00000074331,   OTTMUST00000083784
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36887,604,416 - 87,605,427 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915086 AgrOrtholog
Ensembl Genes ENSMUSG00000005150 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000091048 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000121568 UniProtKB/Swiss-Prot
  ENSMUSP00000122127 UniProtKB/TrEMBL
  ENSMUSP00000122737 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000093357 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000142201 UniProtKB/TrEMBL
  ENSMUST00000149050 UniProtKB/Swiss-Prot
  ENSMUST00000152785 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro G-protein_beta_WD-40_rep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:67836 UniProtKB/Swiss-Prot
MGD MGI:1915086 ENTREZGENE
NCBI Gene 67836 ENTREZGENE
Pfam WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Wdr83 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.334680 ENTREZGENE
UniProt D6RGR4_MOUSE UniProtKB/TrEMBL
  F7C259_MOUSE UniProtKB/TrEMBL
  Q9DAJ4 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q505C2 UniProtKB/Swiss-Prot
  Q8VEB7 UniProtKB/Swiss-Prot
  Q99JX9 UniProtKB/Swiss-Prot
  Q9D235 UniProtKB/Swiss-Prot