Rasd2 (RASD family, member 2) - Rat Genome Database

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Gene: Rasd2 (RASD family, member 2) Mus musculus
Analyze
Symbol: Rasd2
Name: RASD family, member 2
RGD ID: 1332452
MGI Page MGI
Description: Predicted to enable several functions, including G-protein beta-subunit binding activity; GTP binding activity; and ubiquitin conjugating enzyme binding activity. Involved in dopaminergic synaptic transmission and locomotory behavior. Predicted to be located in plasma membrane. Orthologous to human RASD2 (RASD family member 2); INTERACTS WITH 3,4-methylenedioxymethamphetamine; benzo[a]pyrene; benzo[b]fluoranthene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930526B11Rik; AU045414; GTP-binding protein Rhes; ras homolog enriched in striatum; Rh; Rhes; TEM-2; TEM2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39875,940,572 - 75,950,741 (+)NCBIGRCm39mm39
GRCm39 Ensembl875,940,572 - 75,950,741 (+)Ensembl
GRCm38875,213,944 - 75,224,113 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl875,213,944 - 75,224,113 (+)EnsemblGRCm38mm10GRCm38
MGSCv37877,737,843 - 77,748,012 (+)NCBIGRCm37mm9NCBIm37
MGSCv36878,108,883 - 78,120,183 (+)NCBImm8
Celera879,513,759 - 79,523,857 (+)NCBICelera
Cytogenetic Map8C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:15199135   PMID:15489334   PMID:15761153   PMID:16141072   PMID:16141073   PMID:18035555   PMID:18845937  
PMID:19884314   PMID:21267068   PMID:22179112   PMID:23349722   PMID:23380502   PMID:23447628   PMID:24324270   PMID:25556834   PMID:25818655   PMID:26048156   PMID:26190541   PMID:26228524  
PMID:26410627   PMID:26522958   PMID:27405468   PMID:27902448   PMID:28729444   PMID:29904346   PMID:31653935   PMID:31676548   PMID:34648564  


Genomics

Comparative Map Data
Rasd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39875,940,572 - 75,950,741 (+)NCBIGRCm39mm39
GRCm39 Ensembl875,940,572 - 75,950,741 (+)Ensembl
GRCm38875,213,944 - 75,224,113 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl875,213,944 - 75,224,113 (+)EnsemblGRCm38mm10GRCm38
MGSCv37877,737,843 - 77,748,012 (+)NCBIGRCm37mm9NCBIm37
MGSCv36878,108,883 - 78,120,183 (+)NCBImm8
Celera879,513,759 - 79,523,857 (+)NCBICelera
Cytogenetic Map8C1NCBI
RASD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2235,540,831 - 35,553,999 (+)EnsemblGRCh38hg38GRCh38
GRCh382235,532,806 - 35,554,003 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372235,928,853 - 35,950,046 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362234,267,298 - 34,279,992 (+)NCBINCBI36hg18NCBI36
Build 342234,261,851 - 34,274,543NCBI
Celera2219,740,616 - 19,753,311 (+)NCBI
Cytogenetic Map22q12.3NCBI
HuRef2218,896,460 - 18,909,156 (+)NCBIHuRef
CHM1_12235,896,087 - 35,908,779 (+)NCBICHM1_1
Rasd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21913,594,291 - 13,605,016 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1913,594,291 - 13,605,016 (+)Ensembl
Rnor_6.01914,653,198 - 14,663,914 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1914,653,198 - 14,663,914 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01925,770,392 - 25,781,108 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41914,093,270 - 14,103,996 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11914,098,095 - 14,108,822 (+)NCBI
Celera1913,456,744 - 13,467,478 (+)NCBICelera
Cytogenetic Map19p11NCBI
Rasd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540543,191,480 - 43,196,085 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540543,191,530 - 43,196,057 (+)NCBIChiLan1.0ChiLan1.0
RASD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12234,389,825 - 34,403,090 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2234,394,233 - 34,403,090 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02216,549,140 - 16,562,716 (+)NCBIMhudiblu_PPA_v0panPan3
RASD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11028,626,761 - 28,637,861 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1028,626,121 - 28,632,851 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1028,567,593 - 28,577,591 (-)NCBI
ROS_Cfam_1.01029,414,289 - 29,424,287 (-)NCBI
UMICH_Zoey_3.11029,139,536 - 29,149,534 (-)NCBI
UNSW_CanFamBas_1.01029,448,752 - 29,458,766 (-)NCBI
UU_Cfam_GSD_1.01029,629,446 - 29,639,450 (-)NCBI
Rasd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494511,932,176 - 11,942,201 (-)NCBI
SpeTri2.0NW_0049364924,942,590 - 4,954,881 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RASD2
(Sus scrofa - pig)
No map positions available.
RASD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11918,301,361 - 18,315,431 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1918,302,046 - 18,315,492 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666045107,632,836 - 107,646,829 (-)NCBIVero_WHO_p1.0
Rasd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624750285,654 - 294,341 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
AU045414  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38875,223,962 - 75,224,062UniSTSGRCm38
MGSCv37877,747,861 - 77,747,961UniSTSGRCm37
Celera879,523,706 - 79,523,806UniSTS
Cytogenetic Map8C1UniSTS
Whitehead/MRC_RH8805.6UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84429488078295025Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86826982782600347Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined870305375104305495Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined870305375104305495Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871102903105103009Mouse
4141395Char2a_mP. chabaudi malaria resistance QTL 2a (mouse)Not determined7113678390202598Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71287817123895615Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871287817123895615Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined871396181105396393Mouse
1300920Pitm3_mprion incubation time 3 (mouse)Not determined873202495107202598Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)873400000126100000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:917
Count of miRNA genes:550
Interacting mature miRNAs:644
Transcripts:ENSMUST00000132133, ENSMUST00000139848
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000132133   ⟹   ENSMUSP00000120717
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl875,941,130 - 75,948,999 (+)Ensembl
GRCm38.p6 Ensembl875,214,502 - 75,222,371 (+)Ensembl
RefSeq Acc Id: ENSMUST00000139848   ⟹   ENSMUSP00000118070
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl875,940,572 - 75,950,741 (+)Ensembl
GRCm38.p6 Ensembl875,213,944 - 75,224,113 (+)Ensembl
RefSeq Acc Id: NM_029182   ⟹   NP_083458
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39875,940,572 - 75,950,741 (+)NCBI
GRCm38875,213,944 - 75,224,113 (+)ENTREZGENE
MGSCv37877,737,843 - 77,748,012 (+)RGD
Celera879,513,759 - 79,523,857 (+)RGD
cM Map8 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_083458   ⟸   NM_029182
- UniProtKB: P63032 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000118070   ⟸   ENSMUST00000139848
RefSeq Acc Id: ENSMUSP00000120717   ⟸   ENSMUST00000132133

Promoters
RGD ID:6843667
Promoter ID:MM_KWN:54900
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Lung,   Spleen
Transcripts:ENSMUST00000041083,   OTTMUST00000085987
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36877,736,856 - 77,738,617 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1922391 AgrOrtholog
Ensembl Genes ENSMUSG00000034472 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000118070 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000120717 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000132133 UniProtKB/Swiss-Prot
  ENSMUST00000139848 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:75141 UniProtKB/Swiss-Prot
MGD MGI:1922391 ENTREZGENE
NCBI Gene 75141 ENTREZGENE
Pfam Ras UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rasd2 PhenoGen
PROSITE RAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RHO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs small_GTP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P63032 ENTREZGENE
  Q8JZW1_MOUSE UniProtKB/TrEMBL
  RHES_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q9WVD3 UniProtKB/Swiss-Prot