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Gene: Bco1 (beta-carotene oxygenase 1) Mus musculus
Symbol: Bco1
Name: beta-carotene oxygenase 1
Description: Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules. Two alternatively spliced variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Bcdo; Bcdo1; Bcmo1; beta,beta-carotene 15,15'-dioxygenase; beta,beta-carotene 15,15'-monooxygenase; beta-carotene 15, 15'-dioxygenase 1; beta-carotene 15,15' dioxygenase; beta-carotene 15,15'-monooxygenase; beta-carotene cleavage enzyme; beta-carotene dioxygenase 1; beta-CD; betaCMOOX; carotenoid-15,15'-oxygenase; CMO1; Cmoi
Homo sapiens (human) : BCO1 (beta-carotene oxygenase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bco1 (beta-carotene oxygenase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bco1 (beta-carotene oxygenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : BCO1 (beta-carotene oxygenase 1)
Canis lupus familiaris (dog) : BCO1 (beta-carotene oxygenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bco1 (beta-carotene oxygenase 1)
Sus scrofa (pig) : BCO1 (beta-carotene oxygenase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm388117,095,851 - 117,133,720 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv378119,619,765 - 119,657,620 (+)NCBIGRCm37mm9NCBIm37
MGSCv368119,981,842 - 120,019,458 (+)NCBImm8
Celera8121,315,369 - 121,353,295 (+)NCBICelera
Cytogenetic Map8 E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Bco1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1332399
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.