Gene: Kmt5a (lysine methyltransferase 5A) Mus musculus
Symbol: Kmt5a
Name: lysine methyltransferase 5A
Description: ENCODES a protein that exhibits histone-lysine N-methyltransferase activity (ortholog); p53 binding (ortholog); protein-lysine N-methyltransferase activity (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transcription, DNA-templated (ortholog); peptidyl-lysine monomethylation (ortholog); PARTICIPATES IN histone modification pathway; methionine cycle/metabolic pathway; p53 signaling pathway; ASSOCIATED WITH abnormal cell cycle checkpoint function; abnormal cell physiology; abnormal DNA repair; ASSOCIATED WITH prostate cancer (ortholog); Prostatic Neoplasms (ortholog); FOUND IN cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; bis(2-chloroethyl) sulfide
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410195B05Rik; AA617402; AW536475; H4-K20-HMTase KMT5A; H4-K20-HMTase SETD8; histone-lysine N-methyltransferase KMT5A; histone-lysine N-methyltransferase SETD8; lysine-specific methylase 5A; MGC117832; N-lysine methyltransferase KMT5A; N-lysine methyltransferase SETD8; OTTMUSP00000018671; OTTMUSP00000018672; PR-SET7; PR/SET domain-containing protein 07; PR/SET07; SET domain containing (lysine methyltransferase) 8; SET domain-containing protein 8; Setd8
Homo sapiens (human) : KMT5A (lysine methyltransferase 5A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kmt5a (lysine methyltransferase 5A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kmt5a (lysine methyltransferase 5A)
Pan paniscus (bonobo/pygmy chimpanzee) : KMT5A (lysine methyltransferase 5A)
Canis lupus familiaris (dog) : KMT5A (lysine methyltransferase 5A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kmt5a (lysine methyltransferase 5A)
more info ...
Related Pseudogenes: Gm11424   Gm8590   Gm8770  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm385124,439,930 - 124,462,311 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375124,889,939 - 124,912,316 (+)NCBIGRCm37mm9NCBIm37
MGSCv365124,700,548 - 124,722,925 (+)NCBImm8
Celera5121,513,480 - 121,535,737 (+)NCBICelera
Cytogenetic Map5 FNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Kmt5a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1332274
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2018-03-13
Status: ACTIVE