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Gene: Pias3 (protein inhibitor of activated STAT 3) Mus musculus
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Symbol: Pias3
Name: protein inhibitor of activated STAT 3
RGD ID: 1332134
Description: Exhibits SUMO transferase activity. Involved in several processes, including TNFSF11-mediated signaling pathway; negative regulation of osteoclast differentiation; and protein sumoylation. Localizes to cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; eye; genitourinary system; and hair follicle. Orthologous to human PIAS3 (protein inhibitor of activated STAT 3); PARTICIPATES IN interleukin-6 signaling pathway; Jak-Stat signaling pathway; sumoylation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E3 SUMO-protein ligase PIAS3; E3 SUMO-protein transferase PIAS3; MGC27936; P; Pias3l; protein inhibitor of activated STAT protein 3
Orthologs:
Homo sapiens (human) : PIAS3 (protein inhibitor of activated STAT 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pias3 (protein inhibitor of activated STAT, 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pias3 (protein inhibitor of activated STAT 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PIAS3 (protein inhibitor of activated STAT 3)
Canis lupus familiaris (dog) : PIAS3 (protein inhibitor of activated STAT 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pias3 (protein inhibitor of activated STAT 3)
Sus scrofa (pig) : PIAS3 (protein inhibitor of activated STAT 3)
Chlorocebus sabaeus (African green monkey) : PIAS3 (protein inhibitor of activated STAT 3)
Heterocephalus glaber (naked mole-rat) : Pias3 (protein inhibitor of activated STAT 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39396,603,679 - 96,613,386 (+)NCBI
GRCm38396,696,361 - 96,706,070 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl396,696,384 - 96,706,070 (+)EnsemblGRCm38mm10GRCm38
MGSCv37396,500,298 - 96,509,993 (+)NCBIGRCm37mm9NCBIm37
MGSCv36396,781,874 - 96,791,367 (+)NCBImm8
Celera398,105,407 - 98,115,104 (+)NCBICelera
Cytogenetic Map3F2.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pias3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1332134
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.