Actl9 (actin-like 9) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Actl9 (actin-like 9) Mus musculus
Analyze
Symbol: Actl9
Name: actin-like 9
RGD ID: 1332083
MGI Page MGI
Description: Involved in acrosome assembly and fertilization. Predicted to be located in acrosomal vesicle; perinuclear theca; and sperm head. Predicted to be active in actin cytoskeleton. Human ortholog(s) of this gene implicated in spermatogenic failure 53. Orthologous to human ACTL9 (actin like 9).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 1700029I08Rik; actin-like 7-alpha; actin-like 7A; actin-like protein 9; AV259599
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391733,651,873 - 33,653,242 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1733,651,870 - 33,653,242 (+)EnsemblGRCm39 Ensembl
GRCm381733,432,899 - 33,434,268 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1733,432,896 - 33,434,268 (+)EnsemblGRCm38mm10GRCm38
MGSCv371733,569,844 - 33,571,213 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361733,035,344 - 33,036,713 (+)NCBIMGSCv36mm8
Celera1736,194,369 - 36,195,738 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21873635   PMID:33626338  


Genomics

Comparative Map Data
Actl9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391733,651,873 - 33,653,242 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1733,651,870 - 33,653,242 (+)EnsemblGRCm39 Ensembl
GRCm381733,432,899 - 33,434,268 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1733,432,896 - 33,434,268 (+)EnsemblGRCm38mm10GRCm38
MGSCv371733,569,844 - 33,571,213 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361733,035,344 - 33,036,713 (+)NCBIMGSCv36mm8
Celera1736,194,369 - 36,195,738 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
ACTL9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38198,697,400 - 8,698,795 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl198,697,400 - 8,698,795 (-)EnsemblGRCh38hg38GRCh38
GRCh37198,807,750 - 8,809,145 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36198,668,753 - 8,670,172 (-)NCBINCBI36Build 36hg18NCBI36
Celera198,627,110 - 8,628,531 (-)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef198,423,908 - 8,425,329 (-)NCBIHuRef
CHM1_1198,807,253 - 8,808,674 (-)NCBICHM1_1
T2T-CHM13v2.0198,692,998 - 8,694,393 (-)NCBIT2T-CHM13v2.0
Actl9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8714,936,690 - 14,938,067 (+)NCBIGRCr8
mRatBN7.2714,234,504 - 14,235,881 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl714,234,504 - 14,235,881 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx717,237,799 - 17,239,176 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0719,108,924 - 19,110,301 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0716,989,328 - 16,990,705 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0718,310,624 - 18,312,001 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl718,310,624 - 18,312,001 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0718,488,144 - 18,489,521 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4715,944,094 - 15,945,471 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1715,944,166 - 15,945,467 (+)NCBI
Celera713,134,241 - 13,135,618 (+)NCBICelera
Cytogenetic Map7q11NCBI
ACTL9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22013,373,963 - 13,375,376 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11912,491,532 - 12,492,945 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0197,992,891 - 7,994,357 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1198,837,849 - 8,839,272 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl198,837,899 - 8,839,149 (-)Ensemblpanpan1.1panPan2
ACTL9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12053,176,345 - 53,179,880 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2053,178,504 - 53,179,754 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2052,976,304 - 52,979,829 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02053,703,627 - 53,707,156 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2053,705,788 - 53,707,038 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12052,903,687 - 52,907,218 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02053,351,366 - 53,354,889 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02053,582,590 - 53,586,122 (-)NCBIUU_Cfam_GSD_1.0
Actl9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118212,417,697 - 212,419,135 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365885,415,699 - 5,416,946 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365885,415,699 - 5,416,946 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACTL9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl270,658,247 - 70,659,497 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1270,658,141 - 70,659,497 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2271,026,249 - 71,027,727 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACTL9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.168,045,858 - 8,047,510 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl68,045,910 - 8,047,160 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607412,181,584 - 12,183,167 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Actl9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248281,379,751 - 1,380,965 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248281,379,709 - 1,381,237 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Actl9
29 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:290
Count of miRNA genes:251
Interacting mature miRNAs:271
Transcripts:ENSMUST00000087639, ENSMUST00000174088
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172787811943885114Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173311897454107028Mouse
1302038Radpf1_mradiation pulmonary fibrosis 1 (mouse)Not determined171683545533819843Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172771579245622654Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3098790348039703Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172558491443976235Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1300692Blmpf1_mbleomycin-induced pulmonary fibrosis 1 (mouse)Not determined173206165237644775Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
11038694Pas19_mpulmonary adenoma susceptibility 19 (mouse)172971116434754437Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172650533741105037Mouse
25394538Skmw84_mskeletal muscle weight 84, TA (mouse)173266042635520036Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse

Markers in Region
AV259599  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381733,434,124 - 33,434,260UniSTSGRCm38
MGSCv371733,571,069 - 33,571,205UniSTSGRCm37
Celera1736,195,594 - 36,195,730UniSTS
Cytogenetic Map17B1UniSTS
Whitehead/MRC_RH17484.08UniSTS
UniSTS:492876  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381733,433,542 - 33,434,190UniSTSGRCm38
MGSCv371733,570,487 - 33,571,135UniSTSGRCm37
Celera1736,195,012 - 36,195,660UniSTS
Cytogenetic Map17B1UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000174088   ⟹   ENSMUSP00000134564
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1733,651,870 - 33,653,242 (+)Ensembl
GRCm38.p6 Ensembl1733,432,896 - 33,434,268 (+)Ensembl
RefSeq Acc Id: NM_183282   ⟹   NP_899105
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391733,651,873 - 33,653,242 (+)NCBI
GRCm381733,432,899 - 33,434,268 (+)ENTREZGENE
MGSCv371733,569,844 - 33,571,213 (+)RGD
Celera1736,194,369 - 36,195,738 (+)RGD
cM Map17 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_899105 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH89487 (Get FASTA)   NCBI Sequence Viewer  
  AAI00423 (Get FASTA)   NCBI Sequence Viewer  
  AAO17383 (Get FASTA)   NCBI Sequence Viewer  
  BAC25145 (Get FASTA)   NCBI Sequence Viewer  
  EDL10192 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000134564
  ENSMUSP00000134564.2
GenBank Protein Q8CG27 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_899105   ⟸   NM_183282
- UniProtKB: Q497R1 (UniProtKB/Swiss-Prot),   Q5EBK5 (UniProtKB/Swiss-Prot),   Q8CG27 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000134564   ⟸   ENSMUST00000174088

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8CG27-F1-model_v2 AlphaFold Q8CG27 1-415 view protein structure

Promoters
RGD ID:13675570
Promoter ID:EPDNEW_M21934
Type:multiple initiation site
Name:Actl9_1
Description:Mus musculus actin-like 9 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381733,432,899 - 33,432,959EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1916731 AgrOrtholog
Ensembl Genes ENSMUSG00000067416
  ENSMUSG00000092519 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000174088 ENTREZGENE
  ENSMUST00000174088.3 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.420.40 UniProtKB/Swiss-Prot
  Actin, Chain A, domain 4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Actin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATPase_NBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:69481 UniProtKB/Swiss-Prot
MGD MGI:1916731 ENTREZGENE
NCBI Gene 69481 ENTREZGENE
PANTHER PTHR11937 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Actin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Actl9 PhenoGen
PRINTS ACTIN UniProtKB/Swiss-Prot
SMART ACTIN UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53067 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt ACTL9_MOUSE UniProtKB/Swiss-Prot
  Q497R1 ENTREZGENE
  Q5EBK5 ENTREZGENE
  Q8C1R1_MOUSE UniProtKB/TrEMBL
  Q8CG27 ENTREZGENE
UniProt Secondary Q497R1 UniProtKB/Swiss-Prot
  Q5EBK5 UniProtKB/Swiss-Prot