Tmem79 (transmembrane protein 79) - Rat Genome Database

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Gene: Tmem79 (transmembrane protein 79) Mus musculus
Analyze
Symbol: Tmem79
Name: transmembrane protein 79
RGD ID: 1332023
MGI Page MGI
Description: Predicted to enable identical protein binding activity. Involved in several processes, including epithelial cell maturation; establishment of skin barrier; and positive regulation of epidermis development. Acts upstream of or within cornification; cuticle development; and hair follicle morphogenesis. Located in lysosomal membrane and trans-Golgi network membrane. Is expressed in alimentary system; genitourinary system; naris; skin; and thymus. Used to study atopic dermatitis. Orthologous to human TMEM79 (transmembrane protein 79).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 2310042N02Rik; 2310074C17Rik; m; ma; Mat; Matt; matted; mattrin
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39388,235,960 - 88,241,740 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl388,235,962 - 88,243,455 (-)EnsemblGRCm39 Ensembl
GRCm38388,328,653 - 88,334,433 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl388,328,655 - 88,336,148 (-)EnsemblGRCm38mm10GRCm38
MGSCv37388,132,575 - 88,138,355 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36388,414,580 - 88,420,360 (-)NCBIMGSCv36mm8
Celera388,368,227 - 88,374,066 (-)NCBICelera
Cytogenetic Map3F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:489953   PMID:1021597   PMID:4557539   PMID:6160178   PMID:6203959   PMID:7738386   PMID:9746435   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11125038   PMID:11217851  
PMID:12466851   PMID:12477932   PMID:14610273   PMID:15489334   PMID:16141072   PMID:16141073   PMID:17967808   PMID:18799693   PMID:19733297   PMID:21267068   PMID:21677750   PMID:21873635  
PMID:22277940   PMID:23251662   PMID:24060273   PMID:24084074   PMID:24194600   PMID:25446841   PMID:25917818   PMID:29867965   PMID:30463955   PMID:32644214   PMID:33346070   PMID:33894197  
PMID:33910010   PMID:35752300  


Genomics

Comparative Map Data
Tmem79
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39388,235,960 - 88,241,740 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl388,235,962 - 88,243,455 (-)EnsemblGRCm39 Ensembl
GRCm38388,328,653 - 88,334,433 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl388,328,655 - 88,336,148 (-)EnsemblGRCm38mm10GRCm38
MGSCv37388,132,575 - 88,138,355 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36388,414,580 - 88,420,360 (-)NCBIMGSCv36mm8
Celera388,368,227 - 88,374,066 (-)NCBICelera
Cytogenetic Map3F1NCBI
TMEM79
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381156,282,932 - 156,292,443 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1156,282,935 - 156,293,185 (+)EnsemblGRCh38hg38GRCh38
GRCh371156,252,723 - 156,262,234 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361154,519,363 - 154,528,858 (+)NCBINCBI36Build 36hg18NCBI36
Celera1129,325,685 - 129,335,202 (+)NCBICelera
Cytogenetic Map1q22NCBI
HuRef1127,613,374 - 127,622,893 (+)NCBIHuRef
CHM1_11157,648,681 - 157,658,193 (+)NCBICHM1_1
T2T-CHM13v2.01155,421,394 - 155,430,906 (+)NCBIT2T-CHM13v2.0
Tmem79
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22173,798,267 - 173,803,151 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2173,798,267 - 173,803,046 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2180,942,660 - 180,947,434 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02178,965,019 - 178,969,793 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02173,565,073 - 173,569,848 (-)NCBIRnor_WKY
Rnor_6.02187,701,522 - 187,706,452 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2187,697,509 - 187,706,321 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02207,104,465 - 207,109,423 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42180,442,064 - 180,446,842 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12180,392,839 - 180,396,182 (-)NCBI
Celera2167,743,188 - 167,747,904 (-)NCBICelera
Cytogenetic Map2q34NCBI
Tmem79
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555452,420,592 - 2,436,485 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555452,420,594 - 2,436,485 (+)NCBIChiLan1.0ChiLan1.0
TMEM79
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11135,455,766 - 135,465,725 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1135,455,766 - 135,465,426 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01131,625,864 - 131,635,370 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TMEM79
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1741,591,332 - 41,597,993 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl741,591,848 - 41,595,816 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha741,079,282 - 41,085,961 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0741,455,860 - 41,462,538 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl741,456,376 - 41,460,343 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1741,237,244 - 41,243,922 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0741,290,458 - 41,297,136 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0741,574,521 - 41,581,199 (-)NCBIUU_Cfam_GSD_1.0
Tmem79
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505826,488,954 - 26,495,618 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365805,519,577 - 5,525,608 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM79
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl493,762,177 - 93,768,633 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1493,762,176 - 93,768,840 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24102,461,788 - 102,468,826 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM79
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1207,569,757 - 7,579,615 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl207,566,538 - 7,579,605 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660386,865,482 - 6,875,307 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem79
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248851,562,092 - 1,567,303 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248851,562,031 - 1,567,882 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
D3Mit175  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38388,334,866 - 88,335,000UniSTSGRCm38
MGSCv37388,138,788 - 88,138,922UniSTSGRCm37
Celera388,374,499 - 88,374,633UniSTS
Cytogenetic Map3F1UniSTS
cM Map341.0UniSTS
Whitehead Genetic330.6UniSTS
Whitehead/MRC_RH3891.62UniSTS
UniSTS:234723  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38388,329,445 - 88,329,760UniSTSGRCm38
MGSCv37388,133,367 - 88,133,682UniSTSGRCm37
Celera388,369,019 - 88,369,334UniSTS
Cytogenetic Map3F1UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)343954435101607316Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)351907421102307316Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
11039519Ltpr3_mLeishmania tropica response 3 (mouse)356704102100464137Mouse
12880419V125Dq4_mvitamin D active form serum level QTL 4 (mouse)35890730792907307Mouse
4141294Bmd24_mbone mineral density 24 (mouse)Not determined36174006195740241Mouse
1301971Cia5_mcollagen induced arthritis QTL 5 (mouse)Not determined366046658100046795Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)367907333128393649Mouse
11251721Ewc3_methanol withdrawal and consumption 3 (mouse)369568554103568554Mouse
1301791Char4_mP. chabaudi malaria resistance QTL 4 (mouse)Not determined369625509100655290Mouse
1301422Sle11_msystematic lupus erythematosus susceptibility 11 (mouse)Not determined370208904104209042Mouse
11049572Lmr11c_mleishmaniasis resistance 11c (mouse)372139967106140094Mouse
1300982Lmr11_mleishmaniasis resistance 11 (mouse)Not determined372139967106140094Mouse
1300595Tmevd2_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse)Not determined375463302109463549Mouse
1301392Eae3_msusceptibility to experimental allergic encephalomyelitis 3 (mouse)Not determined379548730113548837Mouse
1301947Pcfm3_mperiosteal circumference and femur length 3 (mouse)Not determined381084652115084797Mouse
1301904Iba2_minduction of brown adipocytes 2 (mouse)Not determined382147043116147184Mouse
11041900Lmr11a_mleishmaniasis resistance 11a (mouse)383463991117464137Mouse
11039510Ltpr3d_mLeishmania tropica response 3d (mouse)383463991117464137Mouse
11039511Ltpr3c_mLeishmania tropica response 3c (mouse)383463991117464137Mouse
11039507Ltpr3g_mLeishmania tropica response 3g (mouse)383463991117464137Mouse
11039508Ltpr3f_mLeishmania tropica response 3f (mouse)383463991117464137Mouse
11039509Ltpr3e_mLeishmania tropica response 3e (mouse)383463991117464137Mouse
11039512Ltpr3b_mLeishmania tropica response 3b (mouse)383463991117464137Mouse
1301272Cfsw1_mcystic fibrosis survival to weaning 1 (mouse)Not determined383882912117883044Mouse
4142099Cq3_mcholesterol QTL 3 (mouse)Not determined384888918118889067Mouse
14746984Manh54_mmandible shape 54 (mouse)385289152119289152Mouse
10043981Cia5a_mcollagen induced arthritis QTL 5a (mouse)Not determined38717045489140094Mouse
1357583Sle18_msystematic lupus erythematosus susceptibility 18 (mouse)Not determined387208904125316236Mouse
12738440Twq3_mtestis weight QTL 3 (mouse)387228015121228015Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1371
Count of miRNA genes:388
Interacting mature miRNAs:462
Transcripts:ENSMUST00000001456, ENSMUST00000107552, ENSMUST00000107553
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000001456   ⟹   ENSMUSP00000001456
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl388,235,962 - 88,241,811 (-)Ensembl
GRCm38.p6 Ensembl388,328,655 - 88,334,504 (-)Ensembl
RefSeq Acc Id: ENSMUST00000107552   ⟹   ENSMUSP00000103176
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl388,236,354 - 88,241,761 (-)Ensembl
GRCm38.p6 Ensembl388,329,047 - 88,334,454 (-)Ensembl
RefSeq Acc Id: ENSMUST00000107553   ⟹   ENSMUSP00000103177
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl388,236,353 - 88,241,575 (-)Ensembl
GRCm38.p6 Ensembl388,329,046 - 88,334,268 (-)Ensembl
RefSeq Acc Id: ENSMUST00000193872   ⟹   ENSMUSP00000141830
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl388,240,445 - 88,243,455 (-)Ensembl
GRCm38.p6 Ensembl388,333,138 - 88,336,148 (-)Ensembl
RefSeq Acc Id: NM_024246   ⟹   NP_077208
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39388,235,960 - 88,241,740 (-)NCBI
GRCm38388,328,653 - 88,334,433 (-)ENTREZGENE
MGSCv37388,132,575 - 88,138,355 (-)RGD
Celera388,368,227 - 88,374,066 (-)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006502124   ⟹   XP_006502187
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39388,236,351 - 88,241,639 (-)NCBI
GRCm38388,329,044 - 88,334,329 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006502125   ⟹   XP_006502188
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39388,236,351 - 88,241,639 (-)NCBI
GRCm38388,329,044 - 88,334,329 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_077208   ⟸   NM_024246
- UniProtKB: Q9D709 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006502188   ⟸   XM_006502125
- Peptide Label: isoform X1
- UniProtKB: Q9D709 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006502187   ⟸   XM_006502124
- Peptide Label: isoform X1
- UniProtKB: Q9D709 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000001456   ⟸   ENSMUST00000001456
RefSeq Acc Id: ENSMUSP00000103176   ⟸   ENSMUST00000107552
RefSeq Acc Id: ENSMUSP00000103177   ⟸   ENSMUST00000107553
RefSeq Acc Id: ENSMUSP00000141830   ⟸   ENSMUST00000193872

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D709-F1-model_v2 AlphaFold Q9D709 1-391 view protein structure

Promoters
RGD ID:6834591
Promoter ID:MM_KWN:34836
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   BoneMarrow_0Hour,   ES_Cell,   Kidney,   Liver
Transcripts:BC038331_BC038331,   ENSMUST00000107552,   OTTMUST00000052391,   UC008PUQ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36388,138,006 - 88,139,337 (-)MPROMDB
RGD ID:6881120
Promoter ID:EPDNEW_M4011
Type:multiple initiation site
Name:Tmem79_1
Description:Mus musculus transmembrane protein 79 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38388,334,454 - 88,334,514EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1919163 AgrOrtholog
Ensembl Genes ENSMUSG00000001420 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000001456 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000103176 UniProtKB/Swiss-Prot
  ENSMUSP00000103177 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000141830.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000001456 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000107552 UniProtKB/Swiss-Prot
  ENSMUST00000107553 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000193872.2 UniProtKB/TrEMBL
KEGG Report mmu:71913 UniProtKB/Swiss-Prot
MGD MGI:1919163 ENTREZGENE
NCBI Gene 71913 ENTREZGENE
PhenoGen Tmem79 PhenoGen
UniProt A0A0A6YX45_MOUSE UniProtKB/TrEMBL
  Q9D709 ENTREZGENE, UniProtKB/Swiss-Prot