Mustn1 (musculoskeletal, embryonic nuclear protein 1) - Rat Genome Database

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Gene: Mustn1 (musculoskeletal, embryonic nuclear protein 1) Mus musculus
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Symbol: Mustn1
Name: musculoskeletal, embryonic nuclear protein 1
RGD ID: 1331916
MGI Page MGI
Description: Involved in positive regulation of chondrocyte differentiation; positive regulation of chondrocyte proliferation; and positive regulation of macromolecule metabolic process. Predicted to localize to nucleoplasm. Is expressed in intraembryonic coelom; limb segment; skeletal musculature; and tail paraxial mesenchyme. Orthologous to human MUSTN1 (musculoskeletal, embryonic nuclear protein 1); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110028G01Rik; MGC151316; MGC151318; musculoskeletal embryonic nuclear protein 1; Must; Mustang
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391430,601,214 - 30,603,567 (+)NCBIGRCm39mm39
GRCm39 Ensembl1430,601,157 - 30,603,567 (+)Ensembl
GRCm381430,879,257 - 30,881,610 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1430,879,200 - 30,881,610 (+)EnsemblGRCm38mm10GRCm38
MGSCv371431,692,443 - 31,694,796 (+)NCBIGRCm37mm9NCBIm37
MGSCv361429,708,549 - 29,710,617 (+)NCBImm8
Celera1427,136,627 - 27,138,980 (+)NCBICelera
Cytogenetic Map14BNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14718386   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16731063  
PMID:19410023   PMID:20130207   PMID:20347762   PMID:21267068   PMID:21677750   PMID:23506283   PMID:24194600  


Genomics

Comparative Map Data
Mustn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391430,601,214 - 30,603,567 (+)NCBIGRCm39mm39
GRCm39 Ensembl1430,601,157 - 30,603,567 (+)Ensembl
GRCm381430,879,257 - 30,881,610 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1430,879,200 - 30,881,610 (+)EnsemblGRCm38mm10GRCm38
MGSCv371431,692,443 - 31,694,796 (+)NCBIGRCm37mm9NCBIm37
MGSCv361429,708,549 - 29,710,617 (+)NCBImm8
Celera1427,136,627 - 27,138,980 (+)NCBICelera
Cytogenetic Map14BNCBI
MUSTN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl352,833,114 - 52,835,019 (-)EnsemblGRCh38hg38GRCh38
GRCh38352,833,121 - 52,835,019 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37352,867,137 - 52,869,035 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,842,177 - 52,844,260 (-)NCBINCBI36hg18NCBI36
Celera352,845,956 - 52,848,039 (-)NCBI
Cytogenetic Map3p21.1NCBI
HuRef352,928,926 - 52,931,042 (-)NCBIHuRef
CHM1_1352,819,330 - 52,821,434 (-)NCBICHM1_1
Mustn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2166,072,908 - 6,075,158 (+)NCBI
Rnor_6.0 Ensembl166,962,722 - 6,964,989 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0166,962,737 - 6,964,987 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0166,889,473 - 6,891,723 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4166,311,978 - 6,314,228 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1166,311,975 - 6,314,226 (+)NCBI
Celera169,114,915 - 9,117,165 (-)NCBICelera
Cytogenetic Map16p16NCBI
Mustn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554302,790,090 - 2,793,880 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554302,790,090 - 2,793,880 (-)NCBIChiLan1.0ChiLan1.0
MUSTN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1354,000,547 - 54,004,099 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl354,000,547 - 54,004,099 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0352,774,843 - 52,778,280 (-)NCBIMhudiblu_PPA_v0panPan3
LOC607080
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha2036,976,074 - 36,981,907 (+)NCBI
ROS_Cfam_1.02037,319,303 - 37,350,672 (+)NCBI
UNSW_CanFamBas_1.02037,116,837 - 37,122,681 (+)NCBI
UU_Cfam_GSD_1.02037,394,372 - 37,400,213 (+)NCBI
Mustn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118170,453,686 - 170,455,950 (-)NCBI
SpeTri2.0NW_0049364733,592,259 - 3,594,717 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MUSTN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12214,215,968 - 14,219,524 (-)NCBI
Vero_WHO_p1.0NW_023666041152,678,397 - 152,684,347 (+)NCBI
Mustn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248224,388,562 - 4,395,494 (+)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301991Wta3_mweight adult 3 (mouse)Not determined14383740537837582Mouse
4141550Dbm3_mdiabetes modifier 3 (mouse)Not determined509340539093528Mouse
27226748Femd8_mfemur midshaft diameter 8, 10 week (mouse)14870000046500000Mouse
27226752Femd4_mfemur midshaft diameter 4, 5 week (mouse)14870000047000000Mouse
1300779Dyscalc4_mdystrophic cardiac calcinosis 4 (mouse)Not determined141249091446491050Mouse
4141864Mrdq4_mmodifier of retinal degeneration QTL 4 (mouse)Not determined1254601848527625Mouse
1300544Hypn_mhyperinsulinemia (mouse)Not determined141543865949438808Mouse
1301372Sluc13_msusceptibility to lung cancer 13 (mouse)Not determined141910564753105769Mouse
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420837405121032392Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142101238271648361Mouse
14746973Manh76_mmandible shape 76 (mouse)142256526056565260Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492582457942312Mouse
13506929Recrq10_mrecombination rate in male meiosis QTL 10 (mouse)142820000060900000Mouse
10043886Cia49_mcollagen induced arthritis QTL 49 (mouse)Not determined142975953763759676Mouse
1300998Cia17_mcollagen induced arthritis 17 (mouse)Not determined143009779364097924Mouse
1300909Ath13_matherosclerosis 13 (mouse)Not determined143009779364097924Mouse
27226775Tibl7_mtibia length 7, 5 week (mouse)143060000048600000Mouse
27226744Metcl6_mmetatarsal-calcaneal length 6, 5 week (mouse)143060000052700000Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143060000087700000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:194
Count of miRNA genes:168
Interacting mature miRNAs:180
Transcripts:ENSMUST00000040715
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000040715   ⟹   ENSMUSP00000048427
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1430,879,200 - 30,881,610 (+)Ensembl
RefSeq Acc Id: NM_181390   ⟹   NP_852055
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391430,601,214 - 30,603,567 (+)NCBI
GRCm381430,879,257 - 30,881,610 (+)ENTREZGENE
MGSCv371431,692,443 - 31,694,796 (+)RGD
Celera1427,136,627 - 27,138,980 (+)RGD
cM Map14 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_852055   ⟸   NM_181390
- UniProtKB: Q99JI1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000048427   ⟸   ENSMUST00000040715

Promoters
RGD ID:8681784
Promoter ID:EPDNEW_M18923
Type:initiation region
Name:Mustn1_2
Description:Mus musculus musculoskeletal, embryonic nuclear protein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18924  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381430,879,322 - 30,879,382EPDNEW
RGD ID:8681786
Promoter ID:EPDNEW_M18924
Type:multiple initiation site
Name:Mustn1_1
Description:Mus musculus musculoskeletal, embryonic nuclear protein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18923  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381430,879,542 - 30,879,602EPDNEW
RGD ID:6825196
Promoter ID:MM_KWN:16072
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Lung
Transcripts:NM_181390
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361431,692,446 - 31,692,946 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913425 AgrOrtholog
Ensembl Genes ENSMUSG00000042485 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000048427 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000040715 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro MUSTN1 UniProtKB/Swiss-Prot
KEGG Report mmu:66175 UniProtKB/Swiss-Prot
MGD MGI:1913425 ENTREZGENE
NCBI Gene 66175 ENTREZGENE
Pfam Mustang UniProtKB/Swiss-Prot
PhenoGen Mustn1 PhenoGen
UniProt MSTN1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE