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Gene: Tysnd1 (trypsin domain containing 1) Mus musculus
Symbol: Tysnd1
Name: trypsin domain containing 1
Description: This gene encodes a protease that removes the N-terminal peroxisomal targeting signal (PTS2) from proteins produced in the cytosol, thereby facilitating their import into the peroxisome. The encoded protein is also capable of removing the C-terminal peroxisomal targeting signal (PTS1) from proteins in the peroxisomal matrix. The full-length protein undergoes self-cleavage to produce shorter, potentially inactive, peptides. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1300019N10Rik; peroxisomal leader peptide-processing protease; trypsin domain-containing protein 1
Homo sapiens (human) : TYSND1 (trypsin domain containing 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tysnd1 (trypsin domain containing 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tysnd1 (trypsin domain containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TYSND1 (trypsin domain containing 1)
Canis lupus familiaris (dog) : SAR1A (secretion associated Ras related GTPase 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tysnd1 (trypsin domain containing 1)
Sus scrofa (pig) : TYSND1 (trypsin domain containing 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381061,695,500 - 61,702,773 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371061,158,262 - 61,165,521 (+)NCBIGRCm37mm9NCBIm37
MGSCv361061,090,871 - 61,098,130 (+)NCBImm8
Celera1062,797,020 - 62,804,281 (+)NCBICelera
Cytogenetic Map10 B4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tysnd1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1331903
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.