LBHD2 (LBH domain containing 2) - Rat Genome Database

Name: LBHD2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: LBHD2 (LBH domain containing 2) Canis lupus familiaris

Analyze

Symbol:

LBHD2

Name:

LBH domain containing 2

RGD ID:

13305945

Description:

ASSOCIATED WITH mitochondrial complex IV deficiency nuclear type 17 (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LBH domain-containing protein 2; LOC111097253; uncharacterized LOC111097253; uncharacterized protein LOC111097253

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LBHD2 (LBH domain containing 2)	HGNC	NCBI
Mus musculus (house mouse):	Lbhd2 (LBH domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Lbhd2 (LBH domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LBHD2 (LBH domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Lbhd2 (LBH domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LBHD2 (LBH domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Lbhd2 (LBH domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	70,935,313 - 70,939,013 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	70,447,587 - 70,451,297 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	71,212,177 - 71,215,887 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	71,211,104 - 71,215,892 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	70,875,765 - 70,879,476 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	70,940,515 - 70,944,229 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	71,340,511 - 71,344,225 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

mitochondrial complex IV deficiency nuclear type 17 (ISO)

References

Genomics

Comparative Map Data

LBHD2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	70,935,313 - 70,939,013 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	70,447,587 - 70,451,297 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	71,212,177 - 71,215,887 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	71,211,104 - 71,215,892 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	70,875,765 - 70,879,476 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	70,940,515 - 70,944,229 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	71,340,511 - 71,344,225 (+)	NCBI		UU_Cfam_GSD_1.0

LBHD2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	103,084,210 - 103,090,027 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	103,084,210 - 103,090,027 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	103,550,547 - 103,556,364 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Cytogenetic Map	14	q32.32	NCBI
CHM1_1	14	103,488,342 - 103,494,151 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	97,320,461 - 97,326,278 (+)	NCBI		T2T-CHM13v2.0

Lbhd2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	111,368,485 - 111,378,526 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	111,373,243 - 111,378,524 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	111,402,049 - 111,412,092 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	111,406,809 - 111,412,090 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	112,645,020 - 112,650,288 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	111,854,623 - 111,859,900 (+)	NCBI		MGSCv36	mm8
Celera	12	112,596,929 - 112,602,196 (+)	NCBI		Celera
Cytogenetic Map	12	F1	NCBI
cM Map	12	60.98	NCBI

Lbhd2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	136,263,383 - 136,268,422 (+)	NCBI		GRCr8
mRatBN7.2	6	130,442,388 - 130,447,229 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	130,442,388 - 130,447,229 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	130,612,362 - 130,617,217 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	130,908,350 - 130,913,205 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	130,272,495 - 130,277,336 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	135,856,218 - 135,861,059 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	135,856,218 - 135,861,059 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	144,554,563 - 144,559,562 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	136,162,243 - 136,167,084 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	6	127,999,177 - 128,004,018 (+)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

LBHD2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	104,237,500 - 104,245,005 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	103,453,998 - 103,461,461 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	83,705,828 - 83,712,039 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	103,519,924 - 103,525,795 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	103,521,713 - 103,525,567 (+)	Ensembl	panpan1.1		panPan2

Lbhd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	3,102,374 - 3,107,677 (-)	NCBI		HiC_Itri_2

LBHD2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Vero_WHO_p1.0	NW_023666053	68,252,698 - 68,258,585 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lbhd2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624734	1,594,785 - 1,601,245 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in LBHD2
41 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system
High
Medium
Low			5	5		5
Below cutoff	1	1	7	1	1	1	2	1	10	8	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_022422494	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038484488	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038544063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038608188	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038672988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000096	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000053	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00845031270 ⟹ ENSCAFP00845024479

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	8	71,211,104 - 71,215,892 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845031319 ⟹ ENSCAFP00845024519

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	8	71,212,190 - 71,215,892 (+)	Ensembl

RefSeq Acc Id:

XM_022422494 ⟹ XP_022278202

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	8	70,935,313 - 70,939,013 (+)	NCBI
Dog10K_Boxer_Tasha	8	70,447,587 - 70,451,297 (+)	NCBI

Sequence:

show sequence

TCGGGCTGGCTCCCTTGCCCTTGCGCTGGCCTGGGCGGACATGGCCAAGTGCAGGCGGGATGCT
GGTTTCCACTTGGCTGTGGGTAGAGAGGGCCCCGTCTCGAGTGTGTGAGGGGTGTCTGCTCTCG
GAGACGACCTGGCCATCTTTGCCTCTGGCTGACTTGAACCTGACTCACGCTGCCCCCAGCCTCC
TGGCTCAGAAACCTTTCCCCTGATCCCGGTCCCTGATCTCTGTGCCCTCCCGTAGCCGTTCCCT
GTCCCAGAAGATCCTCTCCTCCCCCCTGGCCTGGCTGCCTCCTGCTCAGCCCTGGGCCTCAGAT
CAGCAGGAAGCCTTCACAGGTCTTAAGGCTGAGTGGGCTTCTCCGATCCGCCTCTGCCCCTCTG
CAACCCTGGGCATGTTGTGCGGTGCCCATCTAGTGCCCCCCGCCCCAATGGTGGGTTTGGGCAG
GGAGCCGTGGTGAGAGAAGTCCAGCTGAAGCAGTGGGCAATGGGCCCAGGGTCGGGTTGGTACA
GGCTGGAGCAGTCTGAAGCTTCCAGAAGGAGAGTGGACTCTAACATCTGTCCCACGGCAGACAC
CTTGTTTCTCCCCGTCTTCGTGCACCCCAACAGCGGCAACAGCATGACTACCCCCCAGCCTGCC
ATGCCAGAGATAAGCCCAGCTGAGGAGGCTGGAGGCCCAGCAGGAAAGGCTGCGGTAGGTGCCC
GGGAGAAGGGCCCTCGGCTGGGCCAGCGGCTGCCCTCCATTGTGGTGGAGTCCAGCGAGGTGGG
CTCTGTGGAGAGTGGGGAGCTGCGTTGGCCCCCTGAGGGCGCCCTGAGGGGGCCAGCCCAGAGC
CAGGCTGCTGCCTCCTCACCGAGTGGGCCGGGGGTACCAGGGAAGGCTCCGGACGATGCTGGCA
GTCAGCATGCCAGCAGCAAGGCGCAGGCCCGCCAGACCCCCCAGTGAGAGGACAGAGCCGTGGT
CGGATTCTGCTGGGGGTGGGGAAGGTCCTGCCAACCCTGCCCCTGCTCGCTGACAGCTGAGAGG
GCCTCAGCCCCAGGGAGCAAGGAGAGCCGGGCCACTGCCTCCTGCTCACGGGGCCTGGCAGGGA
CCACAGGCCTGCCCTCTCCCACCTGCAGCCCAGGGTCTGGATCACACCTCCCTTGTCCTGTGAT
TTGAAGCAGAAATAAAGGCT

hide sequence

RefSeq Acc Id:

XM_038484488 ⟹ XP_038340416

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	8	70,875,765 - 70,879,476 (+)	NCBI

RefSeq Acc Id:

XM_038544063 ⟹ XP_038399991

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	8	71,340,511 - 71,344,225 (+)	NCBI

RefSeq Acc Id:

XM_038608188 ⟹ XP_038464116

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	8	70,940,515 - 70,944,229 (+)	NCBI

RefSeq Acc Id:

XM_038672988 ⟹ XP_038528916

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	8	71,212,177 - 71,215,887 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_022278202	(Get FASTA)	NCBI Sequence Viewer
	XP_038340416	(Get FASTA)	NCBI Sequence Viewer
	XP_038399991	(Get FASTA)	NCBI Sequence Viewer
	XP_038464116	(Get FASTA)	NCBI Sequence Viewer
	XP_038528916	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000053753.2
	ENSCAFP00000054906.1
	ENSCAFP00040016914.1
	ENSCAFP00040016945.1
	ENSCAFP00845024479.1
	ENSCAFP00845024519
	ENSCAFP00845024519.1

RefSeq Acc Id:	XP_022278202 ⟸ XM_022422494
- UniProtKB:	A0A8I3P173 (UniProtKB/TrEMBL), A0A8P0T759 (UniProtKB/TrEMBL), A0A8C0S7H7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGPGSGWYRLEQSEASRRRVDSNICPTADTLFLPVFVHPNSGNSMTTPQPAMPEISPAEEAGGP AGKAAVGAREKGPRLGQRLPSIVVESSEVGSVESGELRWPPEGALRGPAQSQAAASSPSGPGVP GKAPDDAGSQHASSKAQARQTPQ hide sequence

RefSeq Acc Id:

XP_038340416 ⟸ XM_038484488

RefSeq Acc Id:

XP_038464116 ⟸ XM_038608188

RefSeq Acc Id:	XP_038528916 ⟸ XM_038672988
- UniProtKB:	A0A8I3P173 (UniProtKB/TrEMBL), A0A8P0T759 (UniProtKB/TrEMBL), A0A8C0S7H7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038399991 ⟸ XM_038544063
- UniProtKB:	A0A8C0S7H7 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845024519 ⟸ ENSCAFT00845031319

RefSeq Acc Id:

ENSCAFP00845024479 ⟸ ENSCAFT00845031270

Protein Domains

LBH

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000040681	UniProtKB/TrEMBL
	ENSCAFG00040010531	UniProtKB/TrEMBL
	ENSCAFG00845017673	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000057272.3	UniProtKB/TrEMBL
	ENSCAFT00000062286.2	UniProtKB/TrEMBL
	ENSCAFT00040019483.1	UniProtKB/TrEMBL
	ENSCAFT00040019520.1	UniProtKB/TrEMBL
	ENSCAFT00845031270.1	UniProtKB/TrEMBL
	ENSCAFT00845031319	ENTREZGENE
	ENSCAFT00845031319.1	UniProtKB/TrEMBL
InterPro	LBH_dom	UniProtKB/TrEMBL
	LBH_dom_prot	UniProtKB/TrEMBL
NCBI Gene	LOC111097253	ENTREZGENE
PANTHER	LBH DOMAIN-CONTAINING PROTEIN 2	UniProtKB/TrEMBL
	PTHR14987	UniProtKB/TrEMBL
Pfam	Lbh	UniProtKB/TrEMBL
UniProt	A0A8C0S729_CANLF	UniProtKB/TrEMBL
	A0A8C0S7H7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3P173	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3S005_CANLF	UniProtKB/TrEMBL
	A0A8P0P3A1_CANLF	UniProtKB/TrEMBL
	A0A8P0T759	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:111547	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-10-24	LBHD2	LBH domain containing 2	LOC111097253	uncharacterized LOC111097253	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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