Hes6 (hairy and enhancer of split 6) - Rat Genome Database

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Gene: Hes6 (hairy and enhancer of split 6) Mus musculus
Analyze
Symbol: Hes6
Name: hairy and enhancer of split 6
RGD ID: 1323829
MGI Page MGI
Description: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within cell differentiation; nervous system development; and regulation of transcription by RNA polymerase II. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human HES6 (hes family bHLH transcription factor 6).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI326893; bHLHb4; bHLHb41; transcription cofactor HES-6
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39191,339,204 - 91,342,901 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl191,339,205 - 91,341,760 (-)EnsemblGRCm39 Ensembl
GRCm38191,411,483 - 91,414,038 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl191,411,483 - 91,414,038 (-)EnsemblGRCm38mm10GRCm38
MGSCv37193,308,060 - 93,309,799 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36193,241,889 - 93,243,628 (-)NCBIMGSCv36mm8
Celera194,348,702 - 94,350,441 (-)NCBICelera
Cytogenetic Map1DNCBI
cM Map146.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-butoxyethanol  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-amino-2,6-dinitrotoluene  (ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
amiodarone  (ISO)
amitrole  (ISO)
androgen antagonist  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (ISO)
buspirone  (ISO)
butanal  (ISO)
Butylparaben  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (EXP)
ciguatoxin CTX1B  (EXP)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (EXP,ISO)
DDE  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dichloromethane  (EXP)
diclofenac  (EXP)
diethyl maleate  (ISO)
dioxygen  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
enzacamene  (ISO)
epoxiconazole  (EXP,ISO)
flutamide  (ISO)
fonofos  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
glafenine  (ISO)
GW 7647  (ISO)
hydrogen peroxide  (ISO)
ketamine  (ISO)
ketoconazole  (ISO)
lead diacetate  (EXP)
Licochalcone B  (ISO)
linuron  (ISO)
menadione  (ISO)
methimazole  (ISO)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nimesulide  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
parathion  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
prochloraz  (ISO)
procymidone  (ISO)
propiconazole  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium dichromate  (ISO)
styrene  (EXP)
sulfadimethoxine  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichloroethene  (ISO)
Triptolide  (EXP)
tunicamycin  (ISO)
valdecoxib  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10851137   PMID:10906477   PMID:10976052   PMID:11042159   PMID:11044617   PMID:11076679   PMID:11076861   PMID:11959828   PMID:12477932   PMID:12617809  
PMID:12866128   PMID:12972610   PMID:14681479   PMID:14732396   PMID:15226823   PMID:15489334   PMID:15782199   PMID:15905075   PMID:16141072   PMID:16141073   PMID:16452096   PMID:16602821  
PMID:16840533   PMID:17065448   PMID:17611704   PMID:17826772   PMID:18160400   PMID:18270576   PMID:18287559   PMID:18302773   PMID:18554416   PMID:18557763   PMID:18725516   PMID:18778483  
PMID:19191219   PMID:19223466   PMID:19306043   PMID:19369396   PMID:19389377   PMID:19591821   PMID:19666558   PMID:19968968   PMID:20059953   PMID:20211142   PMID:20412781   PMID:20932939  
PMID:21194568   PMID:21267068   PMID:21322090   PMID:21440680   PMID:21501606   PMID:21677750   PMID:21873635   PMID:22323600   PMID:22982728   PMID:23689134   PMID:25149275   PMID:25605944  
PMID:26105991   PMID:26371318   PMID:28162974   PMID:29305158   PMID:29650591   PMID:29661797   PMID:30783098   PMID:31570121   PMID:31988190   PMID:32375051   PMID:32857879   PMID:33591268  
PMID:33898448   PMID:34321999   PMID:35103284   PMID:35320729   PMID:35377797   PMID:37573008  


Genomics

Comparative Map Data
Hes6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39191,339,204 - 91,342,901 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl191,339,205 - 91,341,760 (-)EnsemblGRCm39 Ensembl
GRCm38191,411,483 - 91,414,038 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl191,411,483 - 91,414,038 (-)EnsemblGRCm38mm10GRCm38
MGSCv37193,308,060 - 93,309,799 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36193,241,889 - 93,243,628 (-)NCBIMGSCv36mm8
Celera194,348,702 - 94,350,441 (-)NCBICelera
Cytogenetic Map1DNCBI
cM Map146.12NCBI
HES6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382238,238,267 - 238,240,038 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2238,238,267 - 238,240,662 (-)EnsemblGRCh38hg38GRCh38
GRCh372239,146,908 - 239,148,679 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362238,811,647 - 238,813,409 (-)NCBINCBI36Build 36hg18NCBI36
Build 342238,928,909 - 238,930,670NCBI
Celera2232,859,462 - 232,861,235 (-)NCBICelera
Cytogenetic Map2q37.3NCBI
HuRef2230,937,958 - 230,939,843 (-)NCBIHuRef
CHM1_12239,152,761 - 239,154,534 (-)NCBICHM1_1
T2T-CHM13v2.02238,728,009 - 238,729,780 (-)NCBIT2T-CHM13v2.0
Hes6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8999,449,375 - 99,451,343 (-)NCBIGRCr8
mRatBN7.2992,001,849 - 92,003,562 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl992,001,841 - 92,003,559 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9100,428,608 - 100,430,321 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09105,564,366 - 105,566,079 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09103,927,959 - 103,929,671 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0998,549,698 - 98,551,438 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl998,549,705 - 98,551,438 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0998,225,746 - 98,227,482 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4990,639,890 - 90,641,596 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1990,844,659 - 90,846,365 (-)NCBI
Celera989,542,889 - 89,544,595 (-)NCBICelera
Cytogenetic Map9q36NCBI
Hes6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555422,373,370 - 2,374,272 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555422,373,241 - 2,374,827 (+)NCBIChiLan1.0ChiLan1.0
HES6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213140,871,107 - 140,872,884 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B140,886,074 - 140,887,851 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B125,471,244 - 125,473,025 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B244,321,070 - 244,322,237 (-)NCBIpanpan1.1PanPan1.1panPan2
HES6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12548,710,694 - 48,713,392 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2549,206,100 - 49,207,791 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02549,096,318 - 49,098,006 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2549,096,963 - 49,097,953 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12548,971,418 - 48,973,122 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02548,760,071 - 48,761,750 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02548,992,417 - 48,994,109 (-)NCBIUU_Cfam_GSD_1.0
Hes6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303190,670,176 - 190,671,955 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936525267,753 - 269,527 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936525267,791 - 269,511 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HES6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15137,785,810 - 137,787,694 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115137,785,808 - 137,787,689 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215152,217,871 - 152,219,649 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HES6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110124,263,894 - 124,266,345 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10124,264,456 - 124,265,542 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604075,152,402 - 75,154,849 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hes6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248473,354,501 - 3,355,378 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248473,353,997 - 3,355,484 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hes6
133 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1061
Count of miRNA genes:451
Interacting mature miRNAs:530
Transcripts:ENSMUST00000086851, ENSMUST00000126136, ENSMUST00000132188, ENSMUST00000150520, ENSMUST00000155752
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139132808126445310Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
14746998Mancz1_mmandible centroid size 1 (mouse)15794135191941351Mouse
14747009Manh49_mmandible shape 49 (mouse)15794135191941351Mouse
1300746Skl1_mskeletal size (tail length) 1 (mouse)Not determined15799197791992080Mouse
1357679Egrm1_mearly growth rate, maternal effect 1 (mouse)Not determined15799197791992080Mouse
1301162Skull1_mskull morphology 1 (mouse)Not determined15799197791992080Mouse
1301667Lxw5_mlupus BXSB x NZW 5 (mouse)Not determined15854919192549443Mouse
1301444Alcw5_malcohol withdrawal 5 (mouse)Not determined15854919192549443Mouse
1301748Abbp1_mA/J and C57BL/6 blood pressure 1 (mouse)Not determined162946755120529678Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
27095918Ulnl1_mulna length 1, 5 week (mouse)167339159129727737Mouse
1302146Cocrb1_mcocaine related behavior 1 (mouse)Not determined170133533104139557Mouse
1300976Bmd19_mbone mineral density 19 (mouse)Not determined173266214108838414Mouse
4142394Mssq1_mmandible size and shape QTL 1 (mouse)Not determined73615692107615830Mouse
1301304Hrq3_mheart rate quantitative locus 3 (mouse)Not determined173615692107615830Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173755175147125370Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74516235148715579Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174991977133290937Mouse
1300821Lore1_mloss of righting induced by ethanol 1 (mouse)Not determined17554919192941077Mouse
27095931Pglq1_mpelvic girdle length QTL 1, 5 week (mouse)175976637128527737Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)175976637148775742Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
1558928Mord2_mmodifier of retinal degeneration 2 (mouse)Not determined177123115110536075Mouse
14697706Stsl3a_mSalmonella typhimurium susceptibility locus 3a (mouse)17747663795827725Mouse
4141725Wbcq4_mwhite blood cell quantitative locus 4 (mouse)Not determined179858683113858791Mouse
12050069Nabq1_mnasal bone morphology QTL 1 (mouse)179858683113858791Mouse
13452395Leusq2_mleucocytosis susceptibility QTL 2 (mouse)180245593126386517Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782291982147125370Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182643189135615379Mouse
10412238Alpq5_malcohol preference QTL 5 (mouse)Not determined182832635116832635Mouse
12791004Aath7_maortic arch atherosclerosis 7 (mouse)182832635116832635Mouse
11667074Led2_mlate embryonic death 2 (mouse)185696027117195081Mouse
12790991Aath1_maortic arch atherosclerosis 1 (mouse)186483929120483929Mouse
4141329Mleu1_mmyeloid leukemia survival 1 (mouse)Not determined89786512123786512Mouse
15039333Nmrs1_mNAFLD-associated magnetic resonance shift 1 (mouse)189786512123786512Mouse

Markers in Region
Hes6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38191,411,596 - 91,412,385UniSTSGRCm38
MGSCv37193,308,173 - 93,308,962UniSTSGRCm37
Celera194,348,815 - 94,349,604UniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map1C5UniSTS
cM Map1 UniSTS
AI326893  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38191,411,595 - 91,411,719UniSTSGRCm38
MGSCv37193,308,172 - 93,308,296UniSTSGRCm37
Celera194,348,814 - 94,348,938UniSTS
Cytogenetic Map1C5UniSTS
Cytogenetic Map1DUniSTS
Whitehead/MRC_RH11320.81UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001360899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001360900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB035178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC110510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF247040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF260236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK005022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK007480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC012897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY082192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS419153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000086851   ⟹   ENSMUSP00000084062
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl191,339,205 - 91,340,944 (-)Ensembl
GRCm38.p6 Ensembl191,411,483 - 91,413,222 (-)Ensembl
RefSeq Acc Id: ENSMUST00000126136
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl191,339,205 - 91,340,944 (-)Ensembl
GRCm38.p6 Ensembl191,411,483 - 91,413,222 (-)Ensembl
RefSeq Acc Id: ENSMUST00000132188
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl191,339,205 - 91,340,930 (-)Ensembl
GRCm38.p6 Ensembl191,411,483 - 91,413,208 (-)Ensembl
RefSeq Acc Id: ENSMUST00000150520
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl191,340,070 - 91,341,760 (-)Ensembl
GRCm38.p6 Ensembl191,412,348 - 91,414,038 (-)Ensembl
RefSeq Acc Id: ENSMUST00000155752
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl191,340,009 - 91,340,930 (-)Ensembl
GRCm38.p6 Ensembl191,412,287 - 91,413,208 (-)Ensembl
RefSeq Acc Id: NM_001360899   ⟹   NP_001347828
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39191,339,205 - 91,340,944 (-)NCBI
GRCm38191,411,483 - 91,413,222 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001360900   ⟹   NP_001347829
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39191,339,205 - 91,341,760 (-)NCBI
GRCm38191,411,483 - 91,414,038 (-)NCBI
Sequence:
RefSeq Acc Id: NM_019479   ⟹   NP_062352
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39191,339,205 - 91,340,944 (-)NCBI
GRCm38191,411,483 - 91,413,222 (-)NCBI
MGSCv37193,308,060 - 93,309,799 (-)RGD
Celera194,348,702 - 94,350,441 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036152469   ⟹   XP_036008362
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39191,339,204 - 91,342,901 (-)NCBI
Sequence:
RefSeq Acc Id: NP_062352   ⟸   NM_019479
- Peptide Label: isoform 1
- UniProtKB: Q3U2D7 (UniProtKB/Swiss-Prot),   Q9JHE6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001347829   ⟸   NM_001360900
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001347828   ⟸   NM_001360899
- Peptide Label: isoform 2
RefSeq Acc Id: ENSMUSP00000084062   ⟸   ENSMUST00000086851
RefSeq Acc Id: XP_036008362   ⟸   XM_036152469
- Peptide Label: isoform X1
- UniProtKB: Q9JHE6 (UniProtKB/Swiss-Prot),   Q3U2D7 (UniProtKB/Swiss-Prot)
Protein Domains
bHLH   Orange

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JHE6-F1-model_v2 AlphaFold Q9JHE6 1-224 view protein structure

Promoters
RGD ID:6874486
Promoter ID:EPDNEW_M694
Type:initiation region
Name:Hes6_1
Description:Mus musculus hairy and enhancer of split 6 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38191,413,220 - 91,413,280EPDNEW
RGD ID:6817883
Promoter ID:MM_KWN:1630
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_019479,   OTTMUST00000049447,   OTTMUST00000049448,   UC007CAT.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36193,309,651 - 93,310,151 (-)MPROMDB
RGD ID:6817884
Promoter ID:MM_KWN:1631
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung,   Spleen
Transcripts:OTTMUST00000049446
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36193,310,569 - 93,311,069 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1859852 AgrOrtholog
Ensembl Genes ENSMUSG00000067071 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000086851 ENTREZGENE
  ENSMUST00000086851.2 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot
  6.10.250.980 UniProtKB/Swiss-Prot
InterPro bHLH_dom UniProtKB/Swiss-Prot
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot
  Orange_dom UniProtKB/Swiss-Prot
KEGG Report mmu:55927 UniProtKB/Swiss-Prot
MGD MGI:1859852 ENTREZGENE
NCBI Gene 55927 ENTREZGENE
PANTHER BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED UniProtKB/Swiss-Prot
  TRANSCRIPTION COFACTOR HES-6 UniProtKB/Swiss-Prot
Pfam Hairy_orange UniProtKB/Swiss-Prot
  HLH UniProtKB/Swiss-Prot
PhenoGen Hes6 PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot
  ORANGE UniProtKB/Swiss-Prot
SMART HLH UniProtKB/Swiss-Prot
Superfamily-SCOP Orange domain-like UniProtKB/Swiss-Prot
  SSF47459 UniProtKB/Swiss-Prot
UniProt HES6_MOUSE UniProtKB/Swiss-Prot
  Q3U2D7 ENTREZGENE
  Q9JHE6 ENTREZGENE
UniProt Secondary Q3U2D7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-06-04 Hes6  hairy and enhancer of split 6    hairy and enhancer of split 6 (Drosophila)  Symbol and/or name change 5135510 APPROVED