Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of SENP3 mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SENP3 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Senp3 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SENP3 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | decreases phosphorylation | ISO | Senp3 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased phosphorylation of SENP3 protein | CTD | PMID:23298284 | 2,4-dinitrotoluene | affects expression | ISO | Senp3 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of SENP3 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | ISO | Senp3 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of SENP3 mRNA | CTD | PMID:21346803 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | SENP3 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of SENP3 gene | CTD | PMID:31601247 | 4,4'-sulfonyldiphenol | affects methylation | EXP | | 6480464 | bisphenol S affects the methylation of SENP3 gene | CTD | PMID:31683443 | 4-amino-2,6-dinitrotoluene | affects expression | ISO | Senp3 (Rattus norvegicus) | 6480464 | 4-amino-2 and 6-dinitrotoluene affects the expression of SENP3 mRNA | CTD | PMID:21346803 | 5-azacytidine | increases expression | ISO | SENP3 (Homo sapiens) | 6480464 | Azacitidine results in increased expression of SENP3 mRNA | CTD | PMID:20823114 | 6-propyl-2-thiouracil | increases expression | ISO | Senp3 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of SENP3 mRNA | CTD | PMID:30047161 | acrylamide | decreases expression | ISO | SENP3 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of SENP3 mRNA | CTD | PMID:32763439 | amitrole | increases expression | ISO | Senp3 (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of SENP3 mRNA | CTD | PMID:30047161 | aristolochic acid A | increases expression | ISO | SENP3 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of SENP3 mRNA | CTD | PMID:33212167 | bisphenol A | affects expression | ISO | Senp3 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of SENP3 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Senp3 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of SENP3 mRNA | CTD | PMID:33296240 | bisphenol A | decreases expression | ISO | SENP3 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SENP3 mRNA | CTD | PMID:29275510 | bortezomib | decreases expression | ISO | SENP3 (Homo sapiens) | 6480464 | Bortezomib results in decreased expression of SENP3 mRNA | CTD | PMID:20977926 | cadmium dichloride | decreases methylation | ISO | Senp3 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased methylation of SENP3 promoter | CTD | PMID:22457795 | cadmium dichloride | multiple interactions | ISO | Senp3 (Rattus norvegicus) | 6480464 | SENP3 protein affects the reaction [Cadmium Chloride results in increased cleavage of CASP3 protein] | CTD | PMID:28747609 | cadmium dichloride | decreases expression | ISO | Senp3 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased expression of SENP3 protein | CTD | PMID:28747609 | caffeine | decreases phosphorylation | ISO | SENP3 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of SENP3 protein | CTD | PMID:35688186 | CGP 52608 | multiple interactions | ISO | SENP3 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SENP3 gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of SENP3 mRNA | CTD | PMID:32715474 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of SENP3 mRNA | CTD | PMID:37019170 | cobalt dichloride | decreases expression | ISO | SENP3 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of SENP3 mRNA | CTD | PMID:19320972 and PMID:19376846 | crocidolite asbestos | affects methylation | ISO | SENP3 (Homo sapiens) | 6480464 | Asbestos and Crocidolite affects the methylation of SENP3 3' UTR | CTD | PMID:29523930 | diquat | increases expression | EXP | | 6480464 | Diquat results in increased expression of SENP3 protein | CTD | PMID:36851058 | doxorubicin | decreases expression | ISO | SENP3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of SENP3 mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | ISO | SENP3 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of SENP3 protein | CTD | PMID:23301498 | flutamide | increases expression | ISO | Senp3 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of SENP3 mRNA | CTD | PMID:24136188 | FR900359 | increases phosphorylation | ISO | SENP3 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of SENP3 protein | CTD | PMID:37730182 | Licochalcone B | increases expression | ISO | SENP3 (Homo sapiens) | 6480464 | licochalcone B results in increased expression of SENP3 mRNA | CTD | PMID:33647349 | methimazole | increases expression | ISO | Senp3 (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of SENP3 mRNA | CTD | PMID:30047161 | ozone | multiple interactions | ISO | SENP3 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of SENP3 mRNA | CTD | PMID:35430440 | palbociclib | multiple interactions | ISO | SENP3 (Homo sapiens) | 6480464 | palbociclib inhibits the reaction [[CDK6 protein binds to CCND3 protein] which results in increased phosphorylation of SENP3 protein] | CTD | PMID:22094256 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of SENP3 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | Senp3 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of SENP3 mRNA | CTD | PMID:33387578 | perfluorohexanesulfonic acid | decreases expression | ISO | SENP3 (Homo sapiens) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of SENP3 mRNA | CTD | PMID:25812627 | perfluorohexanesulfonic acid | decreases expression | EXP | | 6480464 | perfluorohexanesulfonic acid results in decreased expression of SENP3 mRNA | CTD | PMID:37995155 | perfluorononanoic acid | decreases expression | ISO | SENP3 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of SENP3 mRNA | CTD | PMID:25812627 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | SENP3 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of SENP3 mRNA | CTD | PMID:25812627 | perfluorooctanoic acid | decreases expression | ISO | SENP3 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of SENP3 mRNA | CTD | PMID:25812627 | phenobarbital | decreases expression | ISO | Senp3 (Rattus norvegicus) | 6480464 | Phenobarbital results in decreased expression of SENP3 mRNA | CTD | PMID:16940010 | pirinixic acid | increases expression | ISO | Senp3 (Rattus norvegicus) | 6480464 | pirinixic acid results in increased expression of SENP3 mRNA | CTD | PMID:16940010 | quercetin | decreases phosphorylation | ISO | SENP3 (Homo sapiens) | 6480464 | Quercetin results in decreased phosphorylation of SENP3 protein | CTD | PMID:35688186 | resveratrol | multiple interactions | ISO | SENP3 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of SENP3 mRNA | CTD | PMID:23557933 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of SENP3 mRNA | CTD | PMID:36209798 | sulfadimethoxine | increases expression | ISO | Senp3 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of SENP3 mRNA | CTD | PMID:30047161 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of SENP3 mRNA | CTD | PMID:33045310 | triticonazole | decreases expression | ISO | Senp3 (Rattus norvegicus) | 6480464 | triticonazole results in decreased expression of SENP3 mRNA | CTD | PMID:36084822 | valproic acid | decreases expression | ISO | SENP3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SENP3 mRNA | CTD | PMID:19101580 and PMID:23527032 | |