PLEKHF2 (pleckstrin homology and FYVE domain containing 2) - Rat Genome Database

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Gene: PLEKHF2 (pleckstrin homology and FYVE domain containing 2) Homo sapiens
Analyze
Symbol: PLEKHF2
Name: pleckstrin homology and FYVE domain containing 2
RGD ID: 1323798
HGNC Page HGNC
Description: Predicted to have phosphatidylinositol binding activity. Predicted to be involved in protein transport. Localizes to transport vesicle; INTERACTS WITH 17beta-estradiol; 2-hydroxypropanoic acid; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: EAPF; endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains; FLJ13187; PH and FYVE domain-containing protein 2; PH domain-containing family F member 2; PHAFIN2; pleckstrin homology domain containing, family F (with FYVE domain) member 2; pleckstrin homology domain-containing family F member 2; ZFYVE18; zinc finger FYVE domain-containing protein 18
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl895,133,785 - 95,156,685 (+)EnsemblGRCh38hg38GRCh38
GRCh38895,133,785 - 95,156,685 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37896,146,013 - 96,168,913 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36896,215,208 - 96,238,089 (+)NCBINCBI36hg18NCBI36
Build 34896,215,213 - 96,238,085NCBI
Celera892,330,955 - 92,353,916 (+)NCBI
Cytogenetic Map8q22.1NCBI
HuRef891,353,593 - 91,376,794 (+)NCBIHuRef
CHM1_1896,186,071 - 96,209,156 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
1. GOA_HUMAN data from the GO Consortium
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11076863   PMID:11230166   PMID:11256614   PMID:12477932   PMID:14702039   PMID:15489334   PMID:15489336   PMID:16189514   PMID:16381901   PMID:17081983   PMID:18288467   PMID:19060904  
PMID:19322201   PMID:19995552   PMID:20923822   PMID:21516116   PMID:21832049   PMID:21873635   PMID:22658674   PMID:22816767   PMID:24416124   PMID:25416956   PMID:26496610   PMID:28152563  
PMID:31515488   PMID:31540324   PMID:32126233   PMID:32296183   PMID:32353859   PMID:33060197  


Genomics

Comparative Map Data
PLEKHF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl895,133,785 - 95,156,685 (+)EnsemblGRCh38hg38GRCh38
GRCh38895,133,785 - 95,156,685 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37896,146,013 - 96,168,913 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36896,215,208 - 96,238,089 (+)NCBINCBI36hg18NCBI36
Build 34896,215,213 - 96,238,085NCBI
Celera892,330,955 - 92,353,916 (+)NCBI
Cytogenetic Map8q22.1NCBI
HuRef891,353,593 - 91,376,794 (+)NCBIHuRef
CHM1_1896,186,071 - 96,209,156 (+)NCBICHM1_1
Plekhf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39410,988,662 - 11,007,619 (-)NCBIGRCm39mm39
GRCm39 Ensembl410,988,662 - 11,007,927 (-)Ensembl
GRCm38410,988,662 - 11,007,619 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl410,988,662 - 11,007,927 (-)EnsemblGRCm38mm10GRCm38
MGSCv37410,915,809 - 10,934,766 (-)NCBIGRCm37mm9NCBIm37
MGSCv36410,915,809 - 10,934,707 (-)NCBImm8
Celera410,797,638 - 10,816,357 (-)NCBICelera
Cytogenetic Map4A1NCBI
Plekhf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2524,091,077 - 24,106,758 (-)NCBI
Rnor_6.0 Ensembl524,240,242 - 24,255,606 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0524,240,241 - 24,255,922 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0528,967,291 - 28,982,656 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4524,835,705 - 24,851,069 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1524,835,704 - 24,851,062 (-)NCBI
Celera523,310,189 - 23,325,553 (-)NCBICelera
Cytogenetic Map5q13NCBI
Plekhf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541711,261,712 - 11,282,038 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541711,261,712 - 11,282,038 (+)NCBIChiLan1.0ChiLan1.0
PLEKHF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1893,972,161 - 93,974,814 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl893,972,170 - 93,972,919 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0891,751,383 - 91,774,320 (+)NCBIMhudiblu_PPA_v0panPan3
PLEKHF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12939,734,189 - 39,760,841 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2939,895,208 - 39,924,759 (-)NCBI
ROS_Cfam_1.02939,935,036 - 39,964,879 (-)NCBI
UMICH_Zoey_3.12939,958,982 - 39,988,654 (-)NCBI
UNSW_CanFamBas_1.02939,945,322 - 39,974,777 (-)NCBI
UU_Cfam_GSD_1.02940,387,539 - 40,416,995 (-)NCBI
Plekhf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530339,656,326 - 39,729,348 (-)NCBI
SpeTri2.0NW_0049365448,063,374 - 8,086,104 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl441,511,342 - 41,535,390 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1441,512,109 - 41,534,932 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PLEKHF2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1890,099,946 - 90,123,573 (+)NCBI
ChlSab1.1 Ensembl890,120,929 - 90,121,678 (+)Ensembl
Plekhf2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247632,506,941 - 2,509,574 (+)NCBI

Position Markers
SHGC-34280  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37896,168,751 - 96,168,884UniSTSGRCh37
Build 36896,237,927 - 96,238,060RGDNCBI36
Celera892,353,754 - 92,353,887RGD
Cytogenetic Map8q22.1UniSTS
HuRef891,376,632 - 91,376,765UniSTS
GeneMap99-GB4 RH Map8439.71UniSTS
Whitehead-RH Map8581.3UniSTS
RH102709  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37896,167,413 - 96,167,602UniSTSGRCh37
Build 36896,236,589 - 96,236,778RGDNCBI36
Celera892,352,416 - 92,352,605RGD
Cytogenetic Map8q22.1UniSTS
HuRef891,375,294 - 91,375,483UniSTS
GeneMap99-GB4 RH Map8438.39UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:745
Count of miRNA genes:515
Interacting mature miRNAs:552
Transcripts:ENST00000315367, ENST00000519516
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1454 1298 544 219 1390 162 3121 611 683 307 921 1205 70 934 1707 4
Low 985 1687 1182 405 557 303 1236 1584 3050 111 539 408 105 1 270 1081 2 2
Below cutoff 6 4 2 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000315367   ⟹   ENSP00000322373
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl895,133,785 - 95,156,685 (+)Ensembl
RefSeq Acc Id: ENST00000519516   ⟹   ENSP00000427792
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl895,134,076 - 95,154,918 (+)Ensembl
RefSeq Acc Id: NM_024613   ⟹   NP_078889
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38895,133,785 - 95,156,685 (+)NCBI
GRCh37896,145,949 - 96,168,913 (+)RGD
Build 36896,215,208 - 96,238,089 (+)NCBI Archive
Celera892,330,955 - 92,353,916 (+)RGD
HuRef891,353,593 - 91,376,794 (+)RGD
CHM1_1896,186,071 - 96,209,156 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_078889   ⟸   NM_024613
- UniProtKB: Q9H8W4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000427792   ⟸   ENST00000519516
RefSeq Acc Id: ENSP00000322373   ⟸   ENST00000315367
Protein Domains
PH

Promoters
RGD ID:7213809
Promoter ID:EPDNEW_H12650
Type:initiation region
Name:PLEKHF2_1
Description:pleckstrin homology and FYVE domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12651  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38895,133,785 - 95,133,845EPDNEW
RGD ID:7213811
Promoter ID:EPDNEW_H12651
Type:initiation region
Name:PLEKHF2_2
Description:pleckstrin homology and FYVE domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12650  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38895,133,915 - 95,133,975EPDNEW
RGD ID:6806943
Promoter ID:HG_KWN:61746
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_024613
Position:
Human AssemblyChrPosition (strand)Source
Build 36896,214,916 - 96,215,416 (+)MPROMDB
RGD ID:6806944
Promoter ID:HG_KWN:61747
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:UC010MBB.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36896,234,401 - 96,234,901 (+)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145049449)x3 copy number gain See cases [RCV000051206] Chr8:241530..145049449 [GRCh38]
Chr8:191530..146274835 [GRCh37]
Chr8:181530..146245639 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000053602] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:244417-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|See cases [RCV000053604] Chr8:244417..145054775 [GRCh38]
Chr8:194417..146280161 [GRCh37]
Chr8:184417..146250965 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.13-22.1(chr8:78672463-95366868)x1 copy number loss See cases [RCV000054262] Chr8:78672463..95366868 [GRCh38]
Chr8:79584698..96379096 [GRCh37]
Chr8:79747253..96448272 [NCBI36]
Chr8:8q21.13-22.1
pathogenic
GRCh38/hg38 8q21.3-22.1(chr8:92283179-95786443)x1 copy number loss See cases [RCV000054265] Chr8:92283179..95786443 [GRCh38]
Chr8:93295407..96798671 [GRCh37]
Chr8:93364583..96867847 [NCBI36]
Chr8:8q21.3-22.1
pathogenic
GRCh38/hg38 8q21.3-22.1(chr8:92287062-95786443)x1 copy number loss See cases [RCV000054277] Chr8:92287062..95786443 [GRCh38]
Chr8:93299290..96798671 [GRCh37]
Chr8:93368466..96867847 [NCBI36]
Chr8:8q21.3-22.1
pathogenic
GRCh38/hg38 8q22.1(chr8:92755532-97792132)x1 copy number loss See cases [RCV000054278] Chr8:92755532..97792132 [GRCh38]
Chr8:93767760..98804360 [GRCh37]
Chr8:93836936..98873536 [NCBI36]
Chr8:8q22.1
pathogenic
GRCh37/hg19 8p12-q24.3(chr8:31936551-146295771)x3 copy number gain not provided [RCV000848192] Chr8:31936551..146295771 [GRCh37]
Chr8:8p12-q24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:94682154-145068656)x3 copy number gain See cases [RCV000134353] Chr8:94682154..145068656 [GRCh38]
Chr8:95694382..146294042 [GRCh37]
Chr8:95763558..146264846 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q21.3-24.23(chr8:86300584-137022587)x3 copy number gain See cases [RCV000135621] Chr8:86300584..137022587 [GRCh38]
Chr8:87312813..138034830 [GRCh37]
Chr8:87381929..138104012 [NCBI36]
Chr8:8q21.3-24.23
pathogenic|likely pathogenic
GRCh38/hg38 8q22.1(chr8:93038175-95667782)x1 copy number loss See cases [RCV000136519] Chr8:93038175..95667782 [GRCh38]
Chr8:94050403..96680010 [GRCh37]
Chr8:94119579..96749186 [NCBI36]
Chr8:8q22.1
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241605-145054781)x3 copy number gain See cases [RCV000138643] Chr8:241605..145054781 [GRCh38]
Chr8:191605..146280167 [GRCh37]
Chr8:181605..146250971 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.3-24.3(chr8:87931152-145068712)x3 copy number gain See cases [RCV000138551] Chr8:87931152..145068712 [GRCh38]
Chr8:88943380..146294098 [GRCh37]
Chr8:89012496..146264902 [NCBI36]
Chr8:8q21.3-24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:77480050-145068712)x3 copy number gain See cases [RCV000139036] Chr8:77480050..145068712 [GRCh38]
Chr8:78392286..146294098 [GRCh37]
Chr8:78554841..146264902 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8q11.1-24.3(chr8:46031340-139285494)x3 copy number gain See cases [RCV000139539] Chr8:46031340..139285494 [GRCh38]
Chr8:46942962..140297737 [GRCh37]
Chr8:47062127..140366919 [NCBI36]
Chr8:8q11.1-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:208048-145070385)x3 copy number gain See cases [RCV000141808] Chr8:208048..145070385 [GRCh38]
Chr8:158048..146295771 [GRCh37]
Chr8:148048..146266575 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8p21.3-q24.3(chr8:21291522-145070385)x3 copy number gain See cases [RCV000142021] Chr8:21291522..145070385 [GRCh38]
Chr8:21149033..146295771 [GRCh37]
Chr8:21193313..146266575 [NCBI36]
Chr8:8p21.3-q24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:226452-145068712)x3 copy number gain See cases [RCV000142858] Chr8:226452..145068712 [GRCh38]
Chr8:176452..146294098 [GRCh37]
Chr8:166452..146264902 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:78614077-145054634)x3 copy number gain See cases [RCV000142597] Chr8:78614077..145054634 [GRCh38]
Chr8:79526312..146280020 [GRCh37]
Chr8:79688867..146250824 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000148092] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.2-24.3(chr8:85765999-145070385)x3 copy number gain See cases [RCV000143659] Chr8:85765999..145070385 [GRCh38]
Chr8:86778228..146295771 [GRCh37]
Chr8:86863079..146266575 [NCBI36]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158991-146280828)x3 copy number gain See cases [RCV000447507] Chr8:158991..146280828 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158049-146295771) copy number gain See cases [RCV000510234] Chr8:158049..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q21.3-24.3(chr8:93047482-141355635)x3 copy number gain See cases [RCV000511761] Chr8:93047482..141355635 [GRCh37]
Chr8:8q21.3-24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158049-146295771)x3 copy number gain See cases [RCV000511095] Chr8:158049..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q21.2-24.3(chr8:86841154-146295771)x3 copy number gain See cases [RCV000511002] Chr8:86841154..146295771 [GRCh37]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8q21.2-24.3(chr8:86841228-142689874)x3 copy number gain See cases [RCV000510854] Chr8:86841228..142689874 [GRCh37]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8q22.1(chr8:93391781-96572606)x1 copy number loss See cases [RCV000512300] Chr8:93391781..96572606 [GRCh37]
Chr8:8q22.1
likely pathogenic
GRCh37/hg19 8p23.1-q24.3(chr8:12490999-146295771)x3 copy number gain See cases [RCV000512169] Chr8:12490999..146295771 [GRCh37]
Chr8:8p23.1-q24.3
pathogenic
GRCh37/hg19 8q21.2-23.3(chr8:86841154-116518125)x3 copy number gain not provided [RCV000683045] Chr8:86841154..116518125 [GRCh37]
Chr8:8q21.2-23.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:164984-146293414)x3 copy number gain not provided [RCV000747254] Chr8:164984..146293414 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:10213-146293414)x3 copy number gain not provided [RCV000747248] Chr8:10213..146293414 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158048-146295771)x3 copy number gain not provided [RCV000848478] Chr8:158048..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q22.1(chr8:95803280-97802022)x3 copy number gain not provided [RCV001259019] Chr8:95803280..97802022 [GRCh37]
Chr8:8q22.1
likely pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:20757 AgrOrtholog
COSMIC PLEKHF2 COSMIC
Ensembl Genes ENSG00000175895 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000322373 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000427792 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000315367 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000519516 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot
GTEx ENSG00000175895 GTEx
HGNC ID HGNC:20757 ENTREZGENE
Human Proteome Map PLEKHF2 Human Proteome Map
InterPro PH-like_dom_sf UniProtKB/Swiss-Prot
  PH_domain UniProtKB/Swiss-Prot
  PH_Phafin UniProtKB/Swiss-Prot
  Znf_FYVE UniProtKB/Swiss-Prot
  Znf_FYVE-rel UniProtKB/Swiss-Prot
  Znf_FYVE_PHD UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
KEGG Report hsa:79666 UniProtKB/Swiss-Prot
NCBI Gene 79666 ENTREZGENE
OMIM 615208 OMIM
Pfam FYVE UniProtKB/Swiss-Prot
  PF00169 UniProtKB/Swiss-Prot
PharmGKB PA128394715 PharmGKB
PROSITE PH_DOMAIN UniProtKB/Swiss-Prot
  ZF_FYVE UniProtKB/Swiss-Prot
SMART FYVE UniProtKB/Swiss-Prot
  SM00233 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57903 UniProtKB/Swiss-Prot
UniProt PKHF2_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 PLEKHF2  pleckstrin homology and FYVE domain containing 2    pleckstrin homology domain containing, family F (with FYVE domain) member 2  Symbol and/or name change 5135510 APPROVED