ERF (ETS2 repressor factor) - Rat Genome Database
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Gene: ERF (ETS2 repressor factor) Homo sapiens
Analyze
Symbol: ERF
Name: ETS2 repressor factor
RGD ID: 1323738
HGNC Page HGNC
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Localizes to cytosol and nucleoplasm. Implicated in craniosynostosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CHYTS; CRS4; ETS domain-containing transcription factor ERF; PE-2; PE2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1942,247,569 - 42,255,128 (-)EnsemblGRCh38hg38GRCh38
GRCh381942,247,569 - 42,255,128 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371942,751,717 - 42,759,309 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,443,557 - 47,451,149 (-)NCBINCBI36hg18NCBI36
Build 341947,443,561 - 47,451,113NCBI
Celera1939,552,513 - 39,560,105 (-)NCBI
Cytogenetic Map19q13.2NCBI
HuRef1939,182,130 - 39,189,922 (-)NCBIHuRef
CHM1_11942,753,395 - 42,760,967 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (ISA)
cytosol  (IDA,TAS)
nucleoplasm  (IDA,TAS)
nucleus  (IBA,IEA)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Abnormal facial shape  (IAGP)
Abnormal form of the vertebral bodies  (IAGP)
Abnormal pulmonary Interstitial morphology  (IAGP)
Abnormal sacrum morphology  (IAGP)
Acanthosis nigricans  (IAGP)
Amblyopia  (IAGP)
Anterior plagiocephaly  (IAGP)
Anteverted nares  (IAGP)
Arnold-Chiari malformation  (IAGP)
Autosomal dominant inheritance  (IAGP)
Blepharophimosis  (IAGP)
Brachycephaly  (IAGP)
Brachydactyly  (IAGP)
Bronchomalacia  (IAGP)
Cerebellar hypoplasia  (IAGP)
Choanal atresia  (IAGP)
Cognitive impairment  (IAGP)
Conductive hearing impairment  (IAGP)
Conjunctivitis  (IAGP)
Convex nasal ridge  (IAGP)
Craniosynostosis  (IAGP)
Delayed speech and language development  (IAGP)
Depressed nasal bridge  (IAGP)
Diminished ability to concentrate  (IAGP)
Dimple chin  (IAGP)
Dolichocephaly  (IAGP)
Downturned corners of mouth  (IAGP)
Ectopic posterior pituitary  (IAGP)
External ear malformation  (IAGP)
Facial asymmetry  (IAGP)
Finger syndactyly  (IAGP)
Flat occiput  (IAGP)
Frontal bossing  (IAGP)
Generalized hypotonia  (IAGP)
Hallux valgus  (IAGP)
Headache  (IAGP)
High forehead  (IAGP)
Hydrocephalus  (IAGP)
Hypertelorism  (IAGP)
Hypertonia  (IAGP)
Hypopigmented skin patches  (IAGP)
Hypoplasia of the maxilla  (IAGP)
Increased intracranial pressure  (IAGP)
Intellectual disability  (IAGP)
Iris coloboma  (IAGP)
Lambdoidal craniosynostosis  (IAGP)
Limitation of joint mobility  (IAGP)
Low-set, posteriorly rotated ears  (IAGP)
Macrocephaly  (IAGP)
Malar flattening  (IAGP)
Melanocytic nevus  (IAGP)
Midface retrusion  (IAGP)
Multiple suture craniosynostosis  (IAGP)
Muscular hypotonia  (IAGP)
Narrow internal auditory canal  (IAGP)
Narrow palate  (IAGP)
Optic atrophy  (IAGP)
Optic nerve hypoplasia  (IAGP)
Pansynostosis  (IAGP)
Pectus excavatum  (IAGP)
Plagiocephaly  (IAGP)
Polyhydramnios  (IAGP)
Posterior plagiocephaly  (IAGP)
Prominent forehead  (IAGP)
Prominent occiput  (IAGP)
Proptosis  (IAGP)
Protruding ear  (IAGP)
Ptosis  (IAGP)
Recurrent respiratory infections  (IAGP)
Respiratory distress  (IAGP)
Respiratory insufficiency  (IAGP)
Retrognathia  (IAGP)
Round ear  (IAGP)
Short columella  (IAGP)
Short nose  (IAGP)
Short stature  (IAGP)
Skeletal dysplasia  (IAGP)
Stomatocytosis  (IAGP)
Strabismus  (IAGP)
Telecanthus  (IAGP)
Thick vermilion border  (IAGP)
Tracheomalacia  (IAGP)
Turricephaly  (IAGP)
References

Additional References at PubMed
PMID:7588608   PMID:9136988   PMID:9192842   PMID:10330152   PMID:11748221   PMID:12062430   PMID:12477932   PMID:12533699   PMID:14611815   PMID:14678752   PMID:14729966   PMID:15057824  
PMID:15489334   PMID:16344560   PMID:16964243   PMID:17081983   PMID:17525531   PMID:17699159   PMID:19274049   PMID:21873635   PMID:22198386   PMID:22990118   PMID:23332764   PMID:23354439  
PMID:26097063   PMID:26186194   PMID:26344095   PMID:26496610   PMID:26598620   PMID:26673895   PMID:26760575   PMID:27173435   PMID:27738187   PMID:28514442   PMID:28515055   PMID:28614298  
PMID:28750683   PMID:30758909   PMID:30804502   PMID:31753913   PMID:31980649   PMID:32296183   PMID:32370745  


Genomics

Comparative Map Data
ERF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1942,247,569 - 42,255,128 (-)EnsemblGRCh38hg38GRCh38
GRCh381942,247,569 - 42,255,128 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371942,751,717 - 42,759,309 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,443,557 - 47,451,149 (-)NCBINCBI36hg18NCBI36
Build 341947,443,561 - 47,451,113NCBI
Celera1939,552,513 - 39,560,105 (-)NCBI
Cytogenetic Map19q13.2NCBI
HuRef1939,182,130 - 39,189,922 (-)NCBIHuRef
CHM1_11942,753,395 - 42,760,967 (-)NCBICHM1_1
Erf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39724,941,985 - 24,950,529 (-)NCBIGRCm39mm39
GRCm38725,242,560 - 25,251,104 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl725,242,561 - 25,250,761 (-)EnsemblGRCm38mm10GRCm38
MGSCv37726,027,579 - 26,035,777 (-)NCBIGRCm37mm9NCBIm37
MGSCv36724,951,320 - 24,959,425 (-)NCBImm8
Celera719,858,364 - 19,866,638 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.73NCBI
Erf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0182,112,449 - 82,120,902 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,112,449 - 82,120,902 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,378,953 - 83,382,937 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,518,385 - 80,527,142 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1180,597,483 - 80,605,113 (-)NCBI
Celera175,273,608 - 75,281,418 (-)NCBICelera
Cytogenetic Map1q21NCBI
Erf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955555654,414 - 665,277 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955555654,945 - 661,097 (+)NCBIChiLan1.0ChiLan1.0
ERF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11947,728,192 - 47,735,808 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1947,728,192 - 47,735,808 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01939,135,757 - 39,143,343 (-)NCBIMhudiblu_PPA_v0panPan3
ERF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1112,117,141 - 112,124,077 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11112,117,338 - 112,124,464 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Erf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936706255,479 - 263,154 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl649,678,871 - 49,685,538 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1649,678,858 - 49,686,422 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2645,597,124 - 45,604,058 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ERF
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1636,452,604 - 36,460,188 (-)NCBI
ChlSab1.1 Ensembl636,452,577 - 36,460,122 (-)Ensembl
Erf
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624907499,913 - 506,719 (+)NCBI

Position Markers
RH79119  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371942,751,749 - 42,751,877UniSTSGRCh37
Build 361947,443,589 - 47,443,717RGDNCBI36
Celera1939,552,545 - 39,552,673RGD
Cytogenetic Map19q13UniSTS
HuRef1939,182,162 - 39,182,290UniSTS
GeneMap99-GB4 RH Map19242.6UniSTS
NCBI RH Map19453.9UniSTS
RH80814  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371942,752,380 - 42,752,626UniSTSGRCh37
Build 361947,444,220 - 47,444,466RGDNCBI36
Celera1939,553,176 - 39,553,422RGD
Cytogenetic Map19q13UniSTS
HuRef1939,182,793 - 39,183,039UniSTS
GeneMap99-GB4 RH Map19239.12UniSTS
ERF__7603  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371942,751,593 - 42,752,411UniSTSGRCh37
Build 361947,443,433 - 47,444,251RGDNCBI36
Celera1939,552,389 - 39,553,207RGD
HuRef1939,182,006 - 39,182,824UniSTS
RH11603  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371942,755,287 - 42,755,510UniSTSGRCh37
Build 361947,447,127 - 47,447,350RGDNCBI36
Celera1939,556,083 - 39,556,306RGD
Cytogenetic Map19q13UniSTS
HuRef1939,185,700 - 39,185,923UniSTS
GeneMap99-GB4 RH Map19239.84UniSTS

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR7-2hsa-miR-7-5pOncomiRDBexternal_infoNANA20978205
MIR7-1hsa-miR-7-5pOncomiRDBexternal_infoNANA20978205

Predicted Target Of
Summary Value
Count of predictions:2724
Count of miRNA genes:803
Interacting mature miRNAs:962
Transcripts:ENST00000222329, ENST00000440177, ENST00000593944, ENST00000595448, ENST00000595941, ENST00000596818, ENST00000598965
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2432 2870 1709 610 1890 455 3624 1382 3331 403 1453 1604 174 1 1204 2056 4
Low 7 121 17 14 57 10 733 815 403 16 7 9 1 732 2 2
Below cutoff 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_042802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001301035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001308402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001312656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017026468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017026469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA961500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB209271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC006486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK300627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK314278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW005463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC022231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM905776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB246848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC299706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC371332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC407368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT583939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U15655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000222329   ⟹   ENSP00000222329
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1942,247,569 - 42,255,128 (-)Ensembl
RefSeq Acc Id: ENST00000440177   ⟹   ENSP00000388173
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1942,248,157 - 42,254,635 (-)Ensembl
RefSeq Acc Id: ENST00000593944   ⟹   ENSP00000469274
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1942,249,593 - 42,253,899 (-)Ensembl
RefSeq Acc Id: ENST00000595448
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1942,249,528 - 42,250,172 (-)Ensembl
RefSeq Acc Id: ENST00000595941
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1942,250,444 - 42,253,894 (-)Ensembl
RefSeq Acc Id: ENST00000596818
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1942,250,130 - 42,255,107 (-)Ensembl
RefSeq Acc Id: ENST00000598965   ⟹   ENSP00000468962
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1942,249,622 - 42,250,441 (-)Ensembl
RefSeq Acc Id: NM_001301035   ⟹   NP_001287964
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,247,569 - 42,254,635 (-)NCBI
CHM1_11942,753,395 - 42,760,438 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001308402   ⟹   NP_001295331
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,247,569 - 42,253,899 (-)NCBI
CHM1_11942,753,395 - 42,756,400 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001312656   ⟹   NP_001299585
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,247,569 - 42,255,128 (-)NCBI
CHM1_11942,753,395 - 42,760,967 (-)NCBI
Sequence:
RefSeq Acc Id: NM_006494   ⟹   NP_006485
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,247,569 - 42,255,128 (-)NCBI
GRCh371942,751,717 - 42,759,309 (-)ENTREZGENE
Build 361947,443,557 - 47,451,149 (-)NCBI Archive
HuRef1939,182,130 - 39,189,922 (-)ENTREZGENE
CHM1_11942,753,395 - 42,760,967 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017026468   ⟹   XP_016881957
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,247,569 - 42,250,918 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017026469   ⟹   XP_016881958
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,247,569 - 42,251,435 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_006485   ⟸   NM_006494
- Peptide Label: isoform 1
- UniProtKB: P50548 (UniProtKB/Swiss-Prot),   A0A024R0L4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001287964   ⟸   NM_001301035
- Peptide Label: isoform 2
- UniProtKB: P50548 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001299585   ⟸   NM_001312656
- Peptide Label: isoform 2
- UniProtKB: P50548 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001295331   ⟸   NM_001308402
- Peptide Label: isoform 2
- UniProtKB: P50548 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016881958   ⟸   XM_017026469
- Peptide Label: isoform X1
- UniProtKB: P50548 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016881957   ⟸   XM_017026468
- Peptide Label: isoform X1
- UniProtKB: P50548 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000468962   ⟸   ENST00000598965
RefSeq Acc Id: ENSP00000388173   ⟸   ENST00000440177
RefSeq Acc Id: ENSP00000222329   ⟸   ENST00000222329
RefSeq Acc Id: ENSP00000469274   ⟸   ENST00000593944
Protein Domains
ETS

Promoters
RGD ID:7240163
Promoter ID:EPDNEW_H25828
Type:initiation region
Name:ERF_3
Description:ETS2 repressor factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H25829  EPDNEW_H25830  EPDNEW_H25831  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,248,204 - 42,248,264EPDNEW
RGD ID:7240165
Promoter ID:EPDNEW_H25829
Type:initiation region
Name:ERF_4
Description:ETS2 repressor factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H25828  EPDNEW_H25830  EPDNEW_H25831  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,249,289 - 42,249,349EPDNEW
RGD ID:7240169
Promoter ID:EPDNEW_H25830
Type:multiple initiation site
Name:ERF_2
Description:ETS2 repressor factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H25828  EPDNEW_H25829  EPDNEW_H25831  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,253,899 - 42,253,959EPDNEW
RGD ID:7240171
Promoter ID:EPDNEW_H25831
Type:initiation region
Name:ERF_1
Description:ETS2 repressor factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H25828  EPDNEW_H25829  EPDNEW_H25830  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,255,128 - 42,255,188EPDNEW
RGD ID:6795532
Promoter ID:HG_KWN:30078
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562,   Lymphoblastoid
Transcripts:UC002OTD.2
Position:
Human AssemblyChrPosition (strand)Source
Build 361947,445,646 - 47,446,146 (-)MPROMDB
RGD ID:6811566
Promoter ID:HG_ACW:41676
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ERFANDGSK3A.FAPR07,   ERFANDGSK3A.OAPR07
Position:
Human AssemblyChrPosition (strand)Source
Build 361947,449,416 - 47,450,517 (-)MPROMDB
RGD ID:6795531
Promoter ID:HG_KWN:30079
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_006494
Position:
Human AssemblyChrPosition (strand)Source
Build 361947,450,816 - 47,451,316 (-)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_006494.4(ERF):c.1244C>T (p.Ala415Val) single nucleotide variant Craniosynostosis 1 [RCV000546427] Chr19:42248868 [GRCh38]
Chr19:42753020 [GRCh37]
Chr19:19q13.2
benign
NM_006494.4(ERF):c.1263G>C (p.Pro421=) single nucleotide variant Craniosynostosis 1 [RCV000558684] Chr19:42248849 [GRCh38]
Chr19:42753001 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.1636C>T (p.Arg546Ter) single nucleotide variant Atrial septal defect [RCV000735402] Chr19:42248476 [GRCh38]
Chr19:42752628 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_006494.4(ERF):c.1104T>C (p.Ser368=) single nucleotide variant Craniosynostosis 1 [RCV000559615] Chr19:42249008 [GRCh38]
Chr19:42753160 [GRCh37]
Chr19:19q13.2
benign
NM_006494.4(ERF):c.547C>T (p.Arg183Ter) single nucleotide variant Craniosynostosis 1 [RCV000534904]|Craniosynostosis 4 [RCV000049336]|Craniosynostosis 4 [RCV000763434] Chr19:42249565 [GRCh38]
Chr19:42753717 [GRCh37]
Chr19:19q13.2
pathogenic
NM_006494.4(ERF):c.891_892del (p.Gly299fs) deletion Craniosynostosis 1 [RCV000794846]|Craniosynostosis 4 [RCV000049337]|Inborn genetic diseases [RCV001267114] Chr19:42249220..42249221 [GRCh38]
Chr19:42753372..42753373 [GRCh37]
Chr19:19q13.2
pathogenic|likely pathogenic
NM_006494.4(ERF):c.256C>T (p.Arg86Cys) single nucleotide variant Craniosynostosis 1 [RCV001060076]|Craniosynostosis 4 [RCV000049338]|not provided [RCV000305113] Chr19:42250332 [GRCh38]
Chr19:42754484 [GRCh37]
Chr19:19q13.2
pathogenic
NM_006494.4(ERF):c.194G>A (p.Arg65Gln) single nucleotide variant Craniosynostosis 4 [RCV000049339] Chr19:42250394 [GRCh38]
Chr19:42754546 [GRCh37]
Chr19:19q13.2
pathogenic
NM_006494.4(ERF):c.1270C>T (p.Gln424Ter) single nucleotide variant Craniosynostosis 4 [RCV000049340] Chr19:42248842 [GRCh38]
Chr19:42752994 [GRCh37]
Chr19:19q13.2
pathogenic
GRCh38/hg38 19q13.12-13.2(chr19:37319377-42738688)x3 copy number gain See cases [RCV000050636] Chr19:37319377..42738688 [GRCh38]
Chr19:37810279..43242840 [GRCh37]
Chr19:42502119..47934680 [NCBI36]
Chr19:19q13.12-13.2
pathogenic
GRCh38/hg38 19q13.2-13.31(chr19:41930894-43141456)x1 copy number loss See cases [RCV000053975] Chr19:41930894..43141456 [GRCh38]
Chr19:42514712..43645608 [GRCh37]
Chr19:47126886..48337448 [NCBI36]
Chr19:19q13.2-13.31
pathogenic
GRCh38/hg38 19p13.2-q13.31(chr19:11227942-44626354)x3 copy number gain See cases [RCV000133888] Chr19:11227942..44626354 [GRCh38]
Chr19:11338618..45129651 [GRCh37]
Chr19:11199618..49821491 [NCBI36]
Chr19:19p13.2-q13.31
pathogenic
NM_006494.4(ERF):c.619C>T (p.Arg207Ter) single nucleotide variant Craniosynostosis 1 [RCV000547799]|Inborn genetic diseases [RCV001265995] Chr19:42249493 [GRCh38]
Chr19:42753645 [GRCh37]
Chr19:19q13.2
pathogenic
NM_006494.4(ERF):c.266A>G (p.Tyr89Cys) single nucleotide variant Chitayat syndrome [RCV000258152]|not provided [RCV000481720] Chr19:42249934 [GRCh38]
Chr19:42754086 [GRCh37]
Chr19:19q13.2
pathogenic|likely pathogenic|not provided
NM_006494.4(ERF):c.23-2A>G single nucleotide variant Craniosynostosis 4 [RCV000203301] Chr19:42250567 [GRCh38]
Chr19:42754719 [GRCh37]
Chr19:19q13.2
pathogenic
NM_006494.4(ERF):c.1A>G (p.Met1Val) single nucleotide variant Craniosynostosis 4 [RCV000203306] Chr19:42254999 [GRCh38]
Chr19:42759151 [GRCh37]
Chr19:19q13.2
pathogenic
NM_006494.4(ERF):c.1569del (p.Leu525fs) deletion not provided [RCV000521416] Chr19:42248543 [GRCh38]
Chr19:42752695 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_006494.4(ERF):c.397_407del (p.Pro133fs) deletion not provided [RCV000728882] Chr19:42249705..42249715 [GRCh38]
Chr19:42753857..42753867 [GRCh37]
Chr19:19q13.2
likely pathogenic
NM_006494.4(ERF):c.840G>A (p.Ser280=) single nucleotide variant not provided [RCV000536254] Chr19:42249272 [GRCh38]
Chr19:42753424 [GRCh37]
Chr19:19q13.2
benign
NM_006494.4(ERF):c.1072_1073del (p.Pro358fs) deletion not provided [RCV000483897] Chr19:42249039..42249040 [GRCh38]
Chr19:42753191..42753192 [GRCh37]
Chr19:19q13.2
likely pathogenic
NM_006494.4(ERF):c.1201_1202del (p.Lys401fs) deletion Craniosynostosis 4 [RCV001263207]|not provided [RCV000485362] Chr19:42248910..42248911 [GRCh38]
Chr19:42753062..42753063 [GRCh37]
Chr19:19q13.2
pathogenic|likely pathogenic
NM_006494.4(ERF):c.247C>T (p.Arg83Trp) single nucleotide variant not specified [RCV000501328] Chr19:42250341 [GRCh38]
Chr19:42754493 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_006494.4(ERF):c.885C>T (p.Ser295=) single nucleotide variant not provided [RCV000917405]|not specified [RCV000504381] Chr19:42249227 [GRCh38]
Chr19:42753379 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.733del (p.Leu245fs) deletion Craniosynostosis 1 [RCV000528500] Chr19:42249379 [GRCh38]
Chr19:42753531 [GRCh37]
Chr19:19q13.2
pathogenic
NM_006494.4(ERF):c.1104_1106TTC[3] (p.Ser373del) microsatellite Craniosynostosis 1 [RCV000533809] Chr19:42248997..42248999 [GRCh38]
Chr19:42753149..42753151 [GRCh37]
Chr19:19q13.2
likely benign
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
NM_006494.4(ERF):c.785del (p.Pro262fs) deletion Inborn genetic diseases [RCV000624075] Chr19:42249327 [GRCh38]
Chr19:42753479 [GRCh37]
Chr19:19q13.2
pathogenic
NM_006494.4(ERF):c.208C>T (p.Arg70Cys) single nucleotide variant Craniosynostosis 1 [RCV000653726] Chr19:42250380 [GRCh38]
Chr19:42754532 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_006494.4(ERF):c.1243_1245del (p.Ala415del) deletion Craniosynostosis 1 [RCV000653727] Chr19:42248867..42248869 [GRCh38]
Chr19:42753019..42753021 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_006494.4(ERF):c.405G>A (p.Val135=) single nucleotide variant not provided [RCV000653730] Chr19:42249707 [GRCh38]
Chr19:42753859 [GRCh37]
Chr19:19q13.2
benign
NM_006494.4(ERF):c.264C>T (p.Tyr88=) single nucleotide variant Craniosynostosis 1 [RCV000653729] Chr19:42249936 [GRCh38]
Chr19:42754088 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.566_567del (p.Asp188_Cys189insTer) deletion Craniosynostosis 1 [RCV000653728]|Craniosynostosis 4 [RCV001254074] Chr19:42249545..42249546 [GRCh38]
Chr19:42753697..42753698 [GRCh37]
Chr19:19q13.2
pathogenic
NM_006494.4(ERF):c.879del (p.Ser295fs) deletion not provided [RCV000514123] Chr19:42249233 [GRCh38]
Chr19:42753385 [GRCh37]
Chr19:19q13.2
likely pathogenic
NM_006494.4(ERF):c.223C>T (p.Gln75Ter) single nucleotide variant Craniosynostosis 1 [RCV000706049] Chr19:42250365 [GRCh38]
Chr19:42754517 [GRCh37]
Chr19:19q13.2
pathogenic
NM_006494.4(ERF):c.-44_22+11del deletion Craniosynostosis 1 [RCV000695296] Chr19:42254967..42255043 [GRCh38]
Chr19:42759119..42759195 [GRCh37]
Chr19:19q13.2
pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
Single allele duplication Schizophrenia [RCV000754211] Chr19:41608672..44315856 [GRCh38]
Chr19:19q13.2-13.31
likely pathogenic
NM_006494.4(ERF):c.813G>A (p.Thr271=) single nucleotide variant not provided [RCV000938286] Chr19:42249299 [GRCh38]
Chr19:42753451 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.257+8C>T single nucleotide variant Craniosynostosis 1 [RCV000878792] Chr19:42250323 [GRCh38]
Chr19:42754475 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.24G>A (p.Gly8=) single nucleotide variant Craniosynostosis 1 [RCV000878791] Chr19:42250564 [GRCh38]
Chr19:42754716 [GRCh37]
Chr19:19q13.2
benign
NM_006494.4(ERF):c.673C>T (p.Leu225=) single nucleotide variant not provided [RCV000878803] Chr19:42249439 [GRCh38]
Chr19:42753591 [GRCh37]
Chr19:19q13.2
benign
NM_006494.4(ERF):c.276C>T (p.Arg92=) single nucleotide variant not provided [RCV000950566] Chr19:42249924 [GRCh38]
Chr19:42754076 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.1046C>T (p.Pro349Leu) single nucleotide variant Craniosynostosis 1 [RCV000870527] Chr19:42249066 [GRCh38]
Chr19:42753218 [GRCh37]
Chr19:19q13.2
benign
NM_006494.4(ERF):c.1192G>A (p.Gly398Ser) single nucleotide variant Craniosynostosis 1 [RCV000870883] Chr19:42248920 [GRCh38]
Chr19:42753072 [GRCh37]
Chr19:19q13.2
benign
NM_006494.4(ERF):c.228G>A (p.Met76Ile) single nucleotide variant Multiple myeloma [RCV000984106] Chr19:42250360 [GRCh38]
Chr19:42754512 [GRCh37]
Chr19:19q13.2
likely pathogenic
NM_006494.4(ERF):c.150G>A (p.Gly50=) single nucleotide variant not provided [RCV000898447] Chr19:42250438 [GRCh38]
Chr19:42754590 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.659C>A (p.Pro220His) single nucleotide variant Craniosynostosis 1 [RCV000950889] Chr19:42249453 [GRCh38]
Chr19:42753605 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.819C>T (p.Thr273=) single nucleotide variant not provided [RCV000972171] Chr19:42249293 [GRCh38]
Chr19:42753445 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.1262C>T (p.Pro421Leu) single nucleotide variant Craniosynostosis 1 [RCV000983822] Chr19:42248850 [GRCh38]
Chr19:42753002 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.285C>T (p.His95=) single nucleotide variant not provided [RCV000921819] Chr19:42249915 [GRCh38]
Chr19:42754067 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.450C>T (p.Ser150=) single nucleotide variant Craniosynostosis 1 [RCV000900679] Chr19:42249662 [GRCh38]
Chr19:42753814 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.247C>A (p.Arg83=) single nucleotide variant not provided [RCV000924400] Chr19:42250341 [GRCh38]
Chr19:42754493 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.1404C>T (p.Pro468=) single nucleotide variant not provided [RCV000901769] Chr19:42248708 [GRCh38]
Chr19:42752860 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.1614G>A (p.Thr538=) single nucleotide variant Craniosynostosis 1 [RCV000878677] Chr19:42248498 [GRCh38]
Chr19:42752650 [GRCh37]
Chr19:19q13.2
benign
NM_006494.4(ERF):c.1527G>C (p.Glu509Asp) single nucleotide variant not provided [RCV000891552] Chr19:42248585 [GRCh38]
Chr19:42752737 [GRCh37]
Chr19:19q13.2
benign
NM_006494.4(ERF):c.1300G>A (p.Glu434Lys) single nucleotide variant Craniosynostosis syndrome [RCV000985270] Chr19:42248812 [GRCh38]
Chr19:42752964 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_006494.4(ERF):c.286A>T (p.Lys96Ter) single nucleotide variant Craniosynostosis 4 [RCV000786998] Chr19:42249914 [GRCh38]
Chr19:42754066 [GRCh37]
Chr19:19q13.2
likely pathogenic
GRCh37/hg19 19q11-13.33(chr19:28271106-49213832)x3 copy number gain not provided [RCV000845733] Chr19:28271106..49213832 [GRCh37]
Chr19:19q11-13.33
pathogenic
NM_006494.4(ERF):c.1177del (p.Glu393fs) deletion not provided [RCV001008368] Chr19:42248935 [GRCh38]
Chr19:42753087 [GRCh37]
Chr19:19q13.2
likely pathogenic
NM_006494.4(ERF):c.383T>G (p.Val128Gly) single nucleotide variant Craniosynostosis syndrome [RCV000985266] Chr19:42249729 [GRCh38]
Chr19:42753881 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_006494.4(ERF):c.1201A>G (p.Lys401Glu) single nucleotide variant Craniosynostosis 1 [RCV001211073] Chr19:42248911 [GRCh38]
Chr19:42753063 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_006494.4(ERF):c.748G>C (p.Val250Leu) single nucleotide variant Craniosynostosis 1 [RCV001222060] Chr19:42249364 [GRCh38]
Chr19:42753516 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_006494.4(ERF):c.427del (p.Arg143fs) deletion Craniosynostosis 1 [RCV001238393] Chr19:42249685 [GRCh38]
Chr19:42753837 [GRCh37]
Chr19:19q13.2
pathogenic
NM_006494.4(ERF):c.1080C>T (p.Val360=) single nucleotide variant not provided [RCV000896302] Chr19:42249032 [GRCh38]
Chr19:42753184 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.942G>A (p.Leu314=) single nucleotide variant not provided [RCV000954340] Chr19:42249170 [GRCh38]
Chr19:42753322 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.280C>T (p.Leu94=) single nucleotide variant not provided [RCV000897778] Chr19:42249920 [GRCh38]
Chr19:42754072 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.1263G>A (p.Pro421=) single nucleotide variant not provided [RCV000895843] Chr19:42248849 [GRCh38]
Chr19:42753001 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.1478G>A (p.Arg493His) single nucleotide variant Craniosynostosis 1 [RCV001239113] Chr19:42248634 [GRCh38]
Chr19:42752786 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_006494.4(ERF):c.257G>A (p.Arg86His) single nucleotide variant Craniosynostosis 1 [RCV001217172] Chr19:42250331 [GRCh38]
Chr19:42754483 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_006494.4(ERF):c.144G>A (p.Trp48Ter) single nucleotide variant Craniosynostosis 1 [RCV001205291] Chr19:42250444 [GRCh38]
Chr19:42754596 [GRCh37]
Chr19:19q13.2
pathogenic
NM_006494.4(ERF):c.532G>C (p.Ala178Pro) single nucleotide variant Craniosynostosis 1 [RCV001061649] Chr19:42249580 [GRCh38]
Chr19:42753732 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_006494.4(ERF):c.1049del (p.Leu350fs) deletion Craniosynostosis 4 [RCV001254631] Chr19:42249063 [GRCh38]
Chr19:42753215 [GRCh37]
Chr19:19q13.2
likely pathogenic
NM_006494.4(ERF):c.1057A>G (p.Met353Val) single nucleotide variant not provided [RCV001257182] Chr19:42249055 [GRCh38]
Chr19:42753207 [GRCh37]
Chr19:19q13.2
likely benign
NM_006494.4(ERF):c.697C>T (p.Arg233Ter) single nucleotide variant Inborn genetic diseases [RCV001266260] Chr19:42249415 [GRCh38]
Chr19:42753567 [GRCh37]
Chr19:19q13.2
pathogenic
NM_006494.4(ERF):c.248G>A (p.Arg83Gln) single nucleotide variant Inborn genetic diseases [RCV001266171] Chr19:42250340 [GRCh38]
Chr19:42754492 [GRCh37]
Chr19:19q13.2
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:3444 AgrOrtholog
COSMIC ERF COSMIC
Ensembl Genes ENSG00000105722 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000222329 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000388173 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000468962 UniProtKB/TrEMBL
  ENSP00000469274 UniProtKB/TrEMBL
Ensembl Transcript ENST00000222329 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000440177 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000593944 UniProtKB/TrEMBL
  ENST00000598965 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000105722 GTEx
HGNC ID HGNC:3444 ENTREZGENE
Human Proteome Map ERF Human Proteome Map
InterPro ERF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ets_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:2077 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 2077 ENTREZGENE
OMIM 600775 OMIM
  611888 OMIM
  617180 OMIM
PANTHER PTHR11849:SF31 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ets UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA27857 PharmGKB
PRINTS ETSDOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ETS_DOMAIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ETS_DOMAIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ETS_DOMAIN_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ETS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A024R0L4 ENTREZGENE, UniProtKB/TrEMBL
  ERF_HUMAN UniProtKB/Swiss-Prot
  M0QX79_HUMAN UniProtKB/TrEMBL
  M0QXN0_HUMAN UniProtKB/TrEMBL
  P50548 ENTREZGENE
UniProt Secondary B2RAP1 UniProtKB/Swiss-Prot
  B7Z4R0 UniProtKB/Swiss-Prot
  Q59G38 UniProtKB/Swiss-Prot
  Q9UPI7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-29 ERF  ETS2 repressor factor    Ets2 repressor factor  Symbol and/or name change 5135510 APPROVED
2011-08-17 ERF  Ets2 repressor factor  ERF  Ets2 repressor factor  Symbol and/or name change 5135510 APPROVED