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Gene: Ptgdr2 (prostaglandin D2 receptor 2) Mus musculus
Symbol: Ptgdr2
Name: prostaglandin D2 receptor 2
Description: Exhibits prostaglandin D receptor activity; prostaglandin F receptor activity; and prostaglandin J receptor activity. Involved in several processes, including adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; negative regulation of male germ cell proliferation; and positive regulation of G protein-coupled receptor signaling pathway. Predicted to localize to the integral component of plasma membrane. Human ortholog(s) of this gene implicated in asthma. Orthologous to human PTGDR2 (prostaglandin D2 receptor 2); INTERACTS WITH 13,14-dihydro-15-ketoprostaglandin D2; 15-deoxy-Delta(12,14)-prostaglandin J2; 3',5'-cyclic AMP.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: chemoattractant receptor-homologous molecule expressed on TH2 cells; Crth2; G protein-coupled receptor 44; G-protein coupled receptor 44; Gpr44; Grp45; MGC130436; PGD2 receptor; prostaglandin D2 receptor CRTH2; putative G-protein coupled receptor 44
Homo sapiens (human) : PTGDR2 (prostaglandin D2 receptor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptgdr2 (prostaglandin D2 receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptgdr2 (prostaglandin D2 receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGDR2 (prostaglandin D2 receptor 2)
Canis lupus familiaris (dog) : PTGDR2 (prostaglandin D2 receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptgdr2 (prostaglandin D2 receptor 2)
Sus scrofa (pig) : PTGDR2 (prostaglandin D2 receptor 2)
Chlorocebus sabaeus (green monkey) : PTGDR2 (prostaglandin D2 receptor 2)
Heterocephalus glaber (naked mole-rat) : Ptgdr2 (prostaglandin D2 receptor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1910,937,160 - 10,942,511 (+)Ensembl
GRCm381910,924,519 - 10,942,511 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371911,011,650 - 11,017,001 (+)NCBIGRCm37mm9NCBIm37
MGSCv361911,004,205 - 11,009,556 (+)NCBImm8
Celera1911,630,059 - 11,635,420 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Ptgdr2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323731
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.