B3gat3 (beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)) - Rat Genome Database

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Gene: B3gat3 (beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)) Mus musculus
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Symbol: B3gat3
Name: beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
RGD ID: 1323699
MGI Page MGI
Description: Predicted to have galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity and protein phosphatase activator activity. Predicted to be involved in several processes, including glycosaminoglycan biosynthetic process; positive regulation of intracellular protein transport; and proteoglycan biosynthetic process. Predicted to localize to Golgi membrane and cis-Golgi network. Is expressed in several structures, including cranium; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Larsen-like syndrome B3GAT3 type. Orthologous to human B3GAT3 (beta-1,3-glucuronyltransferase 3); PARTICIPATES IN chondroitin sulfate biosynthetic pathway; heparan sulfate biosynthetic pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810405M13Rik; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3; GlcA; glcAT-I; glcUAT-I; glucuronosyltransferase I; glucuronosyltransferase-I; glucuronyltransferase I; UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,897,740 - 8,904,600 (+)NCBIGRCm39mm39
GRCm39 Ensembl198,897,738 - 8,904,600 (+)Ensembl
GRCm38198,920,374 - 8,927,236 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,920,374 - 8,927,236 (+)EnsemblGRCm38mm10GRCm38
MGSCv37198,994,883 - 9,001,726 (+)NCBIGRCm37mm9NCBIm37
MGSCv36198,987,438 - 8,994,281 (+)NCBImm8
Celera198,681,170 - 8,688,012 (+)NCBICelera
Cytogenetic Map19ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:8889548   PMID:9506957   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11731273   PMID:12477932   PMID:14610273   PMID:14681479   PMID:15489334   PMID:15782199   PMID:16141072  
PMID:16141073   PMID:18799693   PMID:20059953   PMID:20164174   PMID:20807639   PMID:21267068   PMID:21763480   PMID:21873635  


Genomics

Comparative Map Data
B3gat3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,897,740 - 8,904,600 (+)NCBIGRCm39mm39
GRCm39 Ensembl198,897,738 - 8,904,600 (+)Ensembl
GRCm38198,920,374 - 8,927,236 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,920,374 - 8,927,236 (+)EnsemblGRCm38mm10GRCm38
MGSCv37198,994,883 - 9,001,726 (+)NCBIGRCm37mm9NCBIm37
MGSCv36198,987,438 - 8,994,281 (+)NCBImm8
Celera198,681,170 - 8,688,012 (+)NCBICelera
Cytogenetic Map19ANCBI
B3GAT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1162,615,296 - 62,622,154 (-)EnsemblGRCh38hg38GRCh38
GRCh381162,615,296 - 62,621,986 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371162,382,768 - 62,389,458 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,139,344 - 62,146,024 (-)NCBINCBI36hg18NCBI36
Build 341162,139,344 - 62,146,024NCBI
Celera1159,712,332 - 59,719,018 (-)NCBI
Cytogenetic Map11q12.3NCBI
HuRef1158,711,687 - 58,718,562 (-)NCBIHuRef
CHM1_11162,265,814 - 62,272,710 (-)NCBICHM1_1
B3gat3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21205,817,374 - 205,823,928 (+)NCBI
Rnor_6.0 Ensembl1225,120,061 - 225,126,579 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01225,120,061 - 225,126,579 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01232,057,681 - 232,064,199 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,597,624 - 211,604,142 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11211,756,053 - 211,762,603 (+)NCBI
Celera1203,330,148 - 203,336,695 (+)NCBICelera
Cytogenetic Map1q43NCBI
B3gat3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955599573,426 - 578,032 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955599573,982 - 578,032 (+)NCBIChiLan1.0ChiLan1.0
B3GAT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11161,327,454 - 61,332,323 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,327,454 - 61,332,323 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01157,972,509 - 57,979,702 (-)NCBIMhudiblu_PPA_v0panPan3
B3GAT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11854,020,547 - 54,025,264 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1854,020,736 - 54,024,910 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,625,615 - 52,630,276 (+)NCBI
ROS_Cfam_1.01855,073,284 - 55,077,944 (+)NCBI
UMICH_Zoey_3.11854,169,183 - 54,173,845 (+)NCBI
UNSW_CanFamBas_1.01853,744,264 - 53,748,924 (+)NCBI
UU_Cfam_GSD_1.01854,539,698 - 54,544,358 (+)NCBI
B3gat3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,522,951 - 10,528,316 (+)NCBI
SpeTri2.0NW_004936581636,648 - 642,138 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
B3GAT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl29,119,656 - 9,125,062 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.129,119,621 - 9,125,081 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,465,224 - 8,470,707 (+)NCBISscrofa10.2Sscrofa10.2susScr3
B3GAT3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,282,414 - 11,289,640 (+)NCBI
ChlSab1.1 Ensembl111,282,601 - 11,289,743 (+)Ensembl
Vero_WHO_p1.0NW_023666038108,618,017 - 108,624,892 (+)NCBI
B3gat3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249261,142,544 - 1,145,561 (-)NCBI

Position Markers
M96760  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38198,927,444 - 8,927,585UniSTSGRCm38
MGSCv37199,001,934 - 9,002,075UniSTSGRCm37
Celera198,688,220 - 8,688,361UniSTS
Cytogenetic Map19AUniSTS
cM Map198.0UniSTS
Whitehead/MRC_RH1981.95UniSTS
px-52g8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37198,999,126 - 8,999,412UniSTSGRCm37
MGSCv37X45,868,922 - 45,869,058UniSTSGRCm37
CeleraX36,017,421 - 36,017,557UniSTS
Celera198,685,413 - 8,685,698UniSTS
Cytogenetic Map19AUniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300776Lfp3_mlong free running period 3 (mouse)Not determined19120278703Mouse
4142161Drinksac2_mdrink saccharin 2 (mouse)Not determined120645286Mouse
4142302Nstr1_mnerve sheath tumor resistance QTL 1 (mouse)Not determined19122321310Mouse
1301271Datd_mdopamine transporter density (mouse)Not determined19132362870Mouse
4142406Pbctlp1_mperipheral blood cytotoxic T lymphocyte percentage 1 (mouse)Not determined132897810Mouse
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19167640035676563Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19320000035900000Mouse
1357819Tgct2_mtesticular germ cell tumor 2 (mouse)Not determined19327855120562299Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19334585237345984Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19334585237345984Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19334585237345984Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19334585237345984Mouse
25394536Skmw86_mskeletal muscle weight 86, TA (mouse)1950147898980461Mouse
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19533596239336106Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:259
Count of miRNA genes:200
Interacting mature miRNAs:224
Transcripts:ENSMUST00000096243
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_024256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003952823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB019523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC129217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC012930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000096243   ⟹   ENSMUSP00000093962
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl198,920,374 - 8,927,236 (+)Ensembl
RefSeq Acc Id: ENSMUST00000235193
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl198,920,395 - 8,922,965 (+)Ensembl
RefSeq Acc Id: ENSMUST00000237071   ⟹   ENSMUSP00000157531
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl198,920,484 - 8,926,818 (+)Ensembl
RefSeq Acc Id: NM_024256   ⟹   NP_077218
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39198,897,757 - 8,904,600 (+)NCBI
GRCm38198,920,393 - 8,927,236 (+)ENTREZGENE
MGSCv37198,994,883 - 9,001,726 (+)RGD
Celera198,681,170 - 8,688,012 (+)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_003952823
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39198,897,740 - 8,904,600 (+)NCBI
GRCm38198,920,374 - 8,927,236 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_077218   ⟸   NM_024256
- UniProtKB: P58158 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000157531   ⟸   ENSMUST00000237071
RefSeq Acc Id: ENSMUSP00000093962   ⟸   ENSMUST00000096243

Promoters
RGD ID:13678846
Promoter ID:EPDNEW_M23572
Type:initiation region
Name:B3gat3_1
Description:Mus musculus beta-1,3-glucuronyltransferase 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38198,920,415 - 8,920,475EPDNEW
RGD ID:6829852
Promoter ID:MM_KWN:26322
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_024256,   UC008GNZ.1,   UC008GOA.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36198,994,406 - 8,995,132 (+)MPROMDB
RGD ID:6848720
Promoter ID:MM_TRO:4980
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour
Transcripts:MTR004543.19.317.3
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36199,000,021 - 9,000,521 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1919977 AgrOrtholog
Ensembl Genes ENSMUSG00000003682
  ENSMUSG00000071649 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000093962 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000157531 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000096243 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000237071 UniProtKB/TrEMBL
Gene3D-CATH 3.90.550.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Glyco_trans_43 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-diphossugar_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:72727 UniProtKB/Swiss-Prot
MGD MGI:1919977 ENTREZGENE
NCBI Gene 72727 ENTREZGENE
PANTHER PTHR10896 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Glyco_transf_43 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen B3gat3 PhenoGen
Superfamily-SCOP SSF53448 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A494B978_MOUSE UniProtKB/TrEMBL
  B3GA3_MOUSE UniProtKB/Swiss-Prot
  D4Q8F9_MOUSE UniProtKB/TrEMBL
  P58158 ENTREZGENE
  Q3UJY2_MOUSE UniProtKB/TrEMBL
  Q3UN75_MOUSE UniProtKB/TrEMBL
  Q3USF3_MOUSE UniProtKB/TrEMBL