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Gene: Vgll2 (vestigial like family member 2) Mus musculus
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Symbol: Vgll2
Name: vestigial like family member 2
Description: This gene is a member of the Vestigial-like (Vgl) gene family and is upregulated during muscle differentiation. The product of this gene interacts with and modifies the DNA-binding properties of the transcription factor, TEF-1, and is important for muscle tissue development. Reduced expression of this gene leads to a reduction in the terminal differentiation of muscle cells. Alternate splicing results in multiple protein isoforms. [provided by RefSeq, Jul 2014]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C130057C21Rik; transcription cofactor vestigial-like protein 2; vestigial like 2 homolog; vestigial like 2 homolog (Drosophila); vgl-2; VITO-1; Vito1
Orthologs:
Homo sapiens (human) : VGLL2 (vestigial like family member 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Vgll2 (vestigial-like family member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vgll2 (vestigial like family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : VGLL2 (vestigial like family member 2)
Canis lupus familiaris (dog) : VGLL2 (vestigial like family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vgll2 (vestigial like family member 2)
Sus scrofa (pig) : VGLL2 (vestigial like family member 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381052,022,502 - 52,028,471 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371051,742,492 - 51,748,277 (+)NCBIGRCm37mm9NCBIm37
MGSCv361051,711,101 - 51,716,886 (+)NCBImm8
Celera1052,859,143 - 52,864,995 (+)NCBICelera
Cytogenetic Map10 B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Vgll2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323605
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.