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Gene: Vgll2 (vestigial like family member 2) Mus musculus
Symbol: Vgll2
Name: vestigial like family member 2
Description: This gene is a member of the Vestigial-like (Vgl) gene family and is upregulated during muscle differentiation. The product of this gene interacts with and modifies the DNA-binding properties of the transcription factor, TEF-1, and is important for muscle tissue development. Reduced expression of this gene leads to a reduction in the terminal differentiation of muscle cells. Alternate splicing results in multiple protein isoforms. [provided by RefSeq, Jul 2014]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C130057C21Rik; transcription cofactor vestigial-like protein 2; vestigial like 2 homolog; vestigial like 2 homolog (Drosophila); vgl-2; VITO-1; Vito1
Homo sapiens (human) : VGLL2 (vestigial like family member 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Vgll2 (vestigial-like family member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vgll2 (vestigial like family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : VGLL2 (vestigial like family member 2)
Canis lupus familiaris (dog) : VGLL2 (vestigial like family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vgll2 (vestigial like family member 2)
Sus scrofa (pig) : VGLL2 (vestigial like family member 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381052,022,502 - 52,028,471 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371051,742,492 - 51,748,277 (+)NCBIGRCm37mm9NCBIm37
MGSCv361051,711,101 - 51,716,886 (+)NCBImm8
Celera1052,859,143 - 52,864,995 (+)NCBICelera
Cytogenetic Map10 B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Vgll2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323605
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.