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Gene: TRPM2 (transient receptor potential cation channel subfamily M member 2) Homo sapiens
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Symbol: TRPM2
Name: transient receptor potential cation channel subfamily M member 2
RGD ID: 1323582
Description: Exhibits calcium ion binding activity; calcium-release channel activity; and mono-ADP-D-ribose binding activity. Involved in several processes, including cellular response to hydrogen peroxide; divalent metal ion transport; and protein homotetramerization. Localizes to integral component of plasma membrane and lysosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EREG1; estrogen-responsive element-associated gene 1 protein; KNP3; long transient receptor potential channel 2; LTrpC-2; LTRPC2; MGC133383; NUDT9H; NUDT9L1; transient receptor potential cation channel, subfamily M, member 2; transient receptor potential channel 7; transient receptor potential melastatin 2; TRPC7
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2144,350,163 - 44,443,081 (+)EnsemblGRCh38hg38GRCh38
GRCh382144,350,112 - 44,443,081 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372145,770,046 - 45,862,964 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362144,597,912 - 44,687,392 (+)NCBINCBI36hg18NCBI36
Build 342144,597,998 - 44,687,118NCBI
Celera2130,878,659 - 30,971,052 (+)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2131,143,769 - 31,237,293 (+)NCBIHuRef
CHM1_12145,334,322 - 45,423,804 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TRPM2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323582
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.