H2bc15 (H2B clustered histone 15) - Rat Genome Database

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Gene: H2bc15 (H2B clustered histone 15) Mus musculus
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Symbol: H2bc15
Name: H2B clustered histone 15
RGD ID: 1323489
MGI Page MGI
Description: Predicted to be located in cytosol and nucleoplasm. Orthologous to several human genes including H2BC13 (H2B clustered histone 13).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: H2B 291A; H2bc11; H2bc13; H2bc7; Hist1h; Hist1h2bf; Hist1h2bj; Hist1h2bl; Hist1h2bn; histone 1, H2bn; histone cluster 1, H2bn; histone H2B type 1-F/J/L
RGD Orthologs
Human
Bonobo
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391321,938,246 - 21,938,723 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1321,938,293 - 21,938,673 (+)EnsemblGRCm39 Ensembl
GRCm381321,754,076 - 21,754,553 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1321,754,123 - 21,754,503 (+)EnsemblGRCm38mm10GRCm38
MGSCv371321,845,992 - 21,846,372 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361321,761,588 - 21,761,968 (+)NCBIMGSCv36mm8
Celera1322,029,612 - 22,029,992 (+)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map137.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12040188   PMID:12408966   PMID:17690254   PMID:30550785  


Genomics

Comparative Map Data
H2bc15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391321,938,246 - 21,938,723 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1321,938,293 - 21,938,673 (+)EnsemblGRCm39 Ensembl
GRCm381321,754,076 - 21,754,553 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1321,754,123 - 21,754,503 (+)EnsemblGRCm38mm10GRCm38
MGSCv371321,845,992 - 21,846,372 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361321,761,588 - 21,761,968 (+)NCBIMGSCv36mm8
Celera1322,029,612 - 22,029,992 (+)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map137.95NCBI
H2BC15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38627,838,569 - 27,839,110 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl627,838,545 - 27,855,709 (+)EnsemblGRCh38hg38GRCh38
GRCh37627,806,347 - 27,806,888 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36627,914,343 - 27,914,873 (+)NCBINCBI36Build 36hg18NCBI36
Build 34627,914,418 - 27,914,867NCBI
Celera629,412,400 - 29,412,930 (+)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef627,614,094 - 27,614,542 (+)NCBIHuRef
CHM1_1627,808,587 - 27,809,035 (+)NCBICHM1_1
T2T-CHM13v2.0627,708,242 - 27,708,783 (+)NCBIT2T-CHM13v2.0
LOC100985638
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2542,481,228 - 42,502,436 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1638,483,019 - 38,503,445 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0627,667,886 - 27,685,282 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1628,342,891 - 28,356,723 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl628,343,094 - 28,370,373 (+)Ensemblpanpan1.1panPan2
LOC478743
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha3523,971,560 - 23,972,352 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0 Ensembl3524,178,247 - 24,181,892 (-)EnsemblROS_Cfam_1.0 Ensembl
H2BC15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1721,606,754 - 21,610,955 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2723,110,568 - 23,111,082 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in H2bc15
13 total Variants

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301890Adip7_madiposity 7 (mouse)Not determined13123454672Mouse
1301227Skull19_mskull morphology 19 (mouse)Not determined13123454672Mouse
1301661Tshp13_mtooth shape 13 (mouse)Not determined13123454672Mouse
1301255Cd4ts6_mCD4 T cell subset 6 (mouse)Not determined1316854534168684Mouse
10449140Eosn2_meosinophil differential 2 (mouse)1322131134221311Mouse
15039338Nmrs34_mNAFLD-associated magnetic resonance shift 34 (mouse)1322131134221311Mouse
1301455Bmd3_mbone mineral density 3 (mouse)Not determined13347761237477820Mouse
10045624Heal24_mwound healing/regeneration (mouse)Not determined13347761237477820Mouse
10045625Heal23_mwound healing/regeneration 23 (mouse)Not determined13347761237477820Mouse
1301367Twq1_mtestis weight QTL 1 (mouse)Not determined13361551237615672Mouse
1301733Heal3_mwound healing/regeneration 3 (mouse)Not determined13368020037680343Mouse
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
1558898Hpi1_mhapatic PMN infiltration 1 (mouse)Not determined13441402553101640Mouse
10402494Igmsc1_mimmunoglobulin M secreting cells 1 (mouse)Not determined131716854544918560Mouse
1301984Pbd2_mpeak bone density 2 (mouse)Not determined131718950838947406Mouse
1301880Hypt_mhypertension (mouse)Not determined131815679252156924Mouse
13463469Gssq1_mglomerulosclerosis severity QTL 1 (mouse)131906090853061050Mouse
12880423V25Dq7_mvitamin D inactive form serum level QTL 7 (mouse)131958398353583983Mouse
1301015Sysbp2_msystolic blood pressure 2 (mouse)Not determined132047761259821605Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
1357591Tesq1_mtestis weight QTL 1 (mouse)Not determined132061551255720517Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132061551272385189Mouse
10045618Heal17_mwound healing/regeneration 17 (mouse)Not determined132074693954747056Mouse

Markers in Region
UniSTS:487788  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381321,754,123 - 21,754,503UniSTSGRCm38
MGSCv371321,845,992 - 21,846,372UniSTSGRCm37
Celera1322,029,612 - 22,029,992UniSTS
Cytogenetic Map13A2-A3UniSTS
UniSTS:492759  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381321,753,395 - 21,753,912UniSTSGRCm38
MGSCv371321,845,264 - 21,845,781UniSTSGRCm37
Celera1322,028,884 - 22,029,401UniSTS
Cytogenetic Map13A2-A3UniSTS
Hist1h2bc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map3F1-F2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map13A3.1UniSTS
cM Map13 UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000091709   ⟹   ENSMUSP00000089301
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1321,938,293 - 21,938,673 (+)Ensembl
GRCm38.p6 Ensembl1321,754,123 - 21,754,503 (+)Ensembl
RefSeq Acc Id: NM_178201   ⟹   NP_835508
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391321,938,246 - 21,938,723 (+)NCBI
GRCm381321,754,076 - 21,754,553 (+)NCBI
MGSCv371321,845,992 - 21,846,372 (+)RGD
Celera1322,029,612 - 22,030,042 (+)NCBI
cM Map13 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_835508 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAO06239 (Get FASTA)   NCBI Sequence Viewer  
  EDL32631 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000089301
  ENSMUSP00000089301.3
  ENSMUSP00000089350.2
  ENSMUSP00000100738.2
  ENSMUSP00000106082.2
  ENSMUSP00000106093.2
  ENSMUSP00000106095.2
GenBank Protein P10853 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_835508   ⟸   NM_178201
- UniProtKB: Q5SZZ3 (UniProtKB/Swiss-Prot),   P10853 (UniProtKB/Swiss-Prot),   A0JLV3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000089301   ⟸   ENSMUST00000091709
Protein Domains
Histone H2A/H2B/H3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P10853-F1-model_v2 AlphaFold P10853 1-126 view protein structure

Promoters
RGD ID:8679730
Promoter ID:EPDNEW_M17895
Type:initiation region
Name:Hist1h2bn_1
Description:Mus musculus histone cluster 1, H2bn , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381321,754,076 - 21,754,136EPDNEW
RGD ID:6824032
Promoter ID:MM_KWN:13398
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000110475,   NM_178183,   NM_178201
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361321,844,436 - 21,846,732 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2448407 AgrOrtholog
Ensembl Genes ENSMUSG00000069268 UniProtKB/Swiss-Prot
  ENSMUSG00000069300 UniProtKB/Swiss-Prot
  ENSMUSG00000069303 UniProtKB/Swiss-Prot
  ENSMUSG00000069307 UniProtKB/Swiss-Prot
  ENSMUSG00000094338 UniProtKB/Swiss-Prot
  ENSMUSG00000095217 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000091709 ENTREZGENE
  ENSMUST00000091709.3 UniProtKB/Swiss-Prot
  ENSMUST00000091756.2 UniProtKB/Swiss-Prot
  ENSMUST00000105106.2 UniProtKB/Swiss-Prot
  ENSMUST00000110452.2 UniProtKB/Swiss-Prot
  ENSMUST00000110467.2 UniProtKB/Swiss-Prot
  ENSMUST00000110469.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Histone-fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_H2A/H2B/H3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_H2B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:319180 UniProtKB/Swiss-Prot
  mmu:319183 UniProtKB/Swiss-Prot
  mmu:319185 UniProtKB/Swiss-Prot
  mmu:319187 UniProtKB/Swiss-Prot
  mmu:665596 UniProtKB/Swiss-Prot
  mmu:665622 UniProtKB/Swiss-Prot
MGD MGI:2448407 ENTREZGENE
NCBI Gene 319187 ENTREZGENE
PANTHER HISTONE H2B UniProtKB/TrEMBL
  HISTONE H2B TYPE 1-L UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23428 UniProtKB/Swiss-Prot
Pfam Histone UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen H2bc15 PhenoGen
PRINTS HISTONEH2B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HISTONE_H2B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART H2B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Histone-fold UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A0JLV3 ENTREZGENE, UniProtKB/TrEMBL
  H2B1F_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q5SZZ3 ENTREZGENE
UniProt Secondary Q5SZZ3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-13 H2bc15  H2B clustered histone 15  Hist1h2bn  histone cluster 1, H2bn  Symbol and/or name change 5135510 APPROVED