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Gene: Dtx4 (deltex 4, E3 ubiquitin ligase) Mus musculus
Symbol: Dtx4
Name: deltex 4, E3 ubiquitin ligase
Description: Predicted to have transferase activity and zinc ion binding activity. Predicted to be involved in Notch signaling pathway and protein ubiquitination. Predicted to localize to the cytoplasm. Is expressed in several structures, including central nervous system; genitourinary system; and retina. Orthologous to human DTX4 (deltex E3 ubiquitin ligase 4); PARTICIPATES IN Notch signaling pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,1-dichloroethene; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI449438; BC044798; D930042H13; deltex 4 homolog; deltex4; E3 ubiquitin-protein ligase DTX4; protein deltex-4; RING-type E3 ubiquitin transferase DTX4; RNF155
Homo sapiens (human) : DTX4 (deltex E3 ubiquitin ligase 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dtx4 (deltex E3 ubiquitin ligase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dtx4 (deltex E3 ubiquitin ligase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : DTX4 (deltex E3 ubiquitin ligase 4)
Canis lupus familiaris (dog) : DTX4 (deltex E3 ubiquitin ligase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dtx4 (deltex E3 ubiquitin ligase 4)
Sus scrofa (pig) : DTX4 (deltex E3 ubiquitin ligase 4)
Chlorocebus sabaeus (green monkey) : DTX4 (deltex E3 ubiquitin ligase 4)
Heterocephalus glaber (naked mole-rat) : Dtx4 (deltex E3 ubiquitin ligase 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1912,466,338 - 12,501,454 (-)Ensembl
GRCm381912,466,329 - 12,502,179 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371912,540,826 - 12,576,486 (-)NCBIGRCm37mm9NCBIm37
MGSCv361912,533,381 - 12,568,499 (-)NCBImm8
Celera1913,130,334 - 13,193,491 (-)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Dtx4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323396
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.